Impact of 60 days of 6° head down bed rest on cardiopulmonary function, and the effects of Taikong Yangxin Prescription as a countermeasure.

Objective: To study the changes in cardiopulmonary function induced by mid/long-term simulated microgravity with 6° head down bed rest (HDBR), and the effects of Taikong Yangxin Prescription (, TYP) as a countermeasure.

Methods: Fourteen healthy male volunteers were randomly divided into a control group and a Chinese medicine (CM) group (7 in each group) by a random digital table based on their body weight. Both groups underwent 6° HDBR for 60 days.

Genetic influence on baroreflex sensitivity in normotensive young men.

Background: The dysfunction of baroreflex plays an important role in the pathogenesis of essential hypertension. Recent studies suggest that approximately 40% of the variation in baroreflex sensitivity (BRS) may be accounted for by genetic factors. However, only a few such genetic polymorphisms have been explicitly identified.

[Preventive effects of exercise training on bone loss during 21 d -6 degrees head down bed-rest].

Objective: To observe the protective effects of exercise training during 21 d -6 degrees head down bed rest (HDBR) on bone loss.

Method: Ten healthy young men were randomly divided into HDBR group and HD-BR exercise group, with 5 in each group. Both groups were exposed to -6 degrees head down bed rest for 21 d.

[Effects of 21 d -6 degrees head down bed-rest on pulmonary gas distribution and little airway function].

Objective: To probe the effect of 21 d -6 degrees head down bed-rest (HDBR) on pulmonary gas distribution and little airway function.

Method: The indices of the pulmonary gas distribution and little airway function (delta N2, CV, CV/VC%, LCI) were measured in 16 healthy male subjects before, during and after 21 d -6 degrees HD-BR.

Result: Comparing with before and early days of HDBR, recovery supine delta N2 increased significantly.