Publications by authors named "Zholkiver K"

Moving irradiation of cervical cancer is widely used in radiogynecological practice, mainly as a telecomponent of combined radiation therapy. Its advantages over static irradiation are reduced exposure of the adjacent organs, the absence of skin complications, and a possibility of simultaneous exposure of a primary focus and lymph outflow viae. Biaxial sectoral irradiation was regarded as the most effective method.

View Article and Find Full Text PDF

The study was concerned with 5 and 10-year results of combination treatment (surgery + radiation) of 304 cases of cervical cancer. Recurrence and metastases developed in 32 patients (10.5%).

View Article and Find Full Text PDF

The paper is concerned with a comparative analysis of the immediate and short-term results of chemo- and radiotherapy of 174 patients with well differentiated inoperable lung cancer. The data were presented by the participants of the CMEA cooperative trial (the Hungarian People's Republic, the USSR and the Czechoslovak Socialist Republic over the period of 1976-1980). In the course of a randomized study radiotherapy (at a summary dose of 60 Gy) was given to 98 patients, chemotherapy to 76 (methotrexate and 5-fluorouracil).

View Article and Find Full Text PDF

The concept of a nominal standard dose (NSD) and its further development--the concept of a cumulative radiation effect (CRE), the time-dose-fractionation factor (TDF), etc. are described. The main unit of a biological radiation effect in radiotherapy is CRE, the auxiliary one TDF.

View Article and Find Full Text PDF

A radiobiological substantiation of a method of multifractionation and a review of the results of its clinical application are presented. The authors have developed a method to calculate a cumulative radiation effect and the TDF factor in radiation therapy with multiple dose fractionation in the form of several sessions daily. This method can be used to prevent the radiation-caused complications.

View Article and Find Full Text PDF

Application of moving telegamma therapy as an adjunct to the associated radiation treatment in 399 patients allowed an increase of the dosage up to 6500 rad in the parametrium area. A 5-year survival in stage I was 91.6 +/- 10.

View Article and Find Full Text PDF

Five-year results of treatment in 661 patients with cervical cancer depending on the technic of dose fractionation in external irradiation of the lesser pelvis under static gamma therapy are reported. Two methods of fractionation were employed: small (daily irradiation, the single focal dose of 125--150 rad) and average dose fractionation (irradiation 3 times a week, focal dosage--280--330 rad). In similar initial data (age, stage of the disease, a form of tumor growth and its histological structure) both with the combined and associated radiotherapy the best five-year results were gained with average dose fractionation.

View Article and Find Full Text PDF