Association of serum neuron-specific enolase and bilirubin levels with cerebral dysfunction and prognosis in large-artery atherosclerotic strokes.

Purpose: To explore the association of serum neuron-specific enolase (NSE) and bilirubin levels with cerebral dysfunction in the prognosis of large-artery atherosclerotic (LAA) stroke cases.

Methods: This study included 73 patients who suffered from LAA stroke and were divided into experimental group (n = 41) that had an increased serum NSE and bilirubin level, and control group (n = 32). At day 1, 7, and 14, the National Institutes of Health Stroke Scale (NIHSS) score, serum NSE, and bilirubin levels were measured.