Ribocentre-switch: a database of riboswitches.

Riboswitches are regulatory elements found in the untranslated regions (UTRs) of certain mRNA molecules. They typically comprise two distinct domains: an aptamer domain that can bind to specific small molecules, and an expression platform that controls gene expression. Riboswitches work by undergoing a conformational change upon binding to their specific ligand, thus activating or repressing the genes downstream.

A diagnostic test: diagnostic value of gastrointestinal endoscopy narrow-band imaging (NBI) for colorectal laterally spreading tumor (LST) and submucosal invasion.

Background: Endoscopic ultrasonography is an effective endoscopic examination method for determining the depth of colorectal cancer invasion. Narrow-band imaging (NBI) techniques increase the contrast of vascular structures and more clearly highlight subtle structures on mucosal surfaces, thereby improving the accuracy of endoscopic assessment. This study investigated the diagnostic efficacy of NBI in colorectal laterally spreading tumor (LST) and its submucosal invasion.

Broadband Terahertz Detection by Laser Plasma with Balanced Optical Bias.

Using a controlled optical bias and balanced geometry, we propose a new scheme for broadband terahertz detection by laser-gas interaction without high-voltage manipulation. Compared to the conventional optical bias scheme, the common noise is reduced and the dynamic range as well as the signal-to-noise ratio are doubled. It provides a simple alternative for coherent broadband terahertz detection.

Wind-Direction Estimation from Single X-Band Marine Radar Image Improvement by Utilizing the DWT and Azimuth-Scale Expansion Method.

In this study, a method based on the discrete wavelet transform (DWT) and azimuth-scale expansion is presented to retrieve the sea-surface wind direction from a single X-band marine radar image. The algorithm first distinguishes rain-free and rain-contaminated radar images based on the occlusion zero-pixel percentage and then discards the rain-contaminated images. The radar image whose occlusion areas have been removed is decomposed into different low-frequency sub-images by the 2D DWT, and the appropriate low-frequency sub-image is selected.

Sea Clutter Suppression and Target Detection Algorithm of Marine Radar Image Sequence Based on Spatio-Temporal Domain Joint Filtering.

In marine radar target detection, sea clutter will cause a large number of missed alarms and false alarms, which will affect the accuracy of target detection. In order to suppress sea clutter effectively, a sea clutter suppression and target detection algorithm of marine radar image sequence based on spatio-temporal domain joint filtering is proposed in this paper. The proposed method is to add a sea clutter suppression link before detecting the target.

Sparsity Adaptive Matching Pursuit Detection Algorithm Based on Compressed Sensing for Radar Signals.

In this paper, the application of the emerging compressed sensing (CS) theory and the geometric characteristics of the targets in radar images are investigated. Currently, the signal detection algorithms based on the CS theory require knowing the prior knowledge of the sparsity of target signals. However, in practice, it is often impossible to know the sparsity in advance.

[Increased expressions of programmed death 1 (PD-1) and its ligands in peripheral CD3(+) T cells and CD19(+) B cells in patients with hepatocellular carcinoma].

Objective To investigate the changes of programmed death 1 (PD-1) and ligands, as well as interferon-γ (IFN-γ) in peripheral blood mononuclear cells (PBMCs) of patients with hepatocellular carcinoma (HCC). Methods The peripheral blood was collected from 15 early HCC patients, 13 progressive HCC patients and 12 healthy volunteers. PBMCs was isolated from the peripheral blood.

Epigenetic silencing of miRNA-9 is correlated with promoter-proximal CpG island hypermethylation in gastric cancer in vitro and in vivo.

Silencing of protein-coding tumor suppressor genes (TSGs) by CpG island hypermethylation is a common occurrence in gastric cancer (GC). Here, we examine if tumor suppressor microRNAs (miRNAs) are silenced in a similar manner. Real-time quantitative PCR (RTQ-PCR) was employed to investigate the expression level of four candidate miRNAs in GC tissues (n=30) and cell lines.

[Study on technological characters of anaerobic-aerobic bioreactor landfill].

A technology of anaerobic-aerobic landfill bioreactor aimed at reusing landfill site is studied, and it's based on landfill bioreactor technology. A set of stimulating equipment is designed, and the technology characters are studied. In the anaerobic period, technological conditions are controlled by the means of leachate recirculation.

[Studies of on-site night soil and kitchen garbage treatment].

The biological treatment technique of collection at source and disposition on-site of night soil and kitchen garbage were presented. By design project of overall technics, the lab-scale experiments were performed. It was revealed that water consumption of vacuum closestool was about 1 L/time.