Dimension Prediction and Microstructure Study of Wire Arc Additive Manufactured 316L Stainless Steel Based on Artificial Neural Network and Finite Element Simulation.

The dimensional accuracy and microstructure affect the service performance of parts fabricated by wire arc additive manufacturing (WAAM). Regulating the geometry and microstructure of such parts presents a challenge. The coupling method of an artificial neural network and finite element (FE) is proposed in this research for this purpose.

Hsa_circ_0031891 targets miR-579-3p to enhance HMGB1 expression and regulate PDGF-BB-induced human aortic vascular smooth muscle cell proliferation, migration, and dedifferentiation.

Atherosclerosis (AS) is an underlying cause of the majority of coronary artery disease (CAD), in which proliferation, migration, and dedifferentiation of vascular smooth muscle cells (VSMCs) exert vital roles. It has been reported that circular RNAs (circRNAs) are associated with the VSMCs function. Here, we undertook to explore the biological function and mechanism of hsa_circ_0031891 in a platelet-derived growth factor-BB (PDGF-BB)-induced AS cell model.

Temperature measurement and error analysis of the transverse plane of oil-jet-lubrication herringbone gear with infrared pyrometers.

Frictional power losses of high-speed and heavy-load herringbone gearboxes increase the temperature of the gearbox. Thus, real-time surface temperature measurement is significant for evaluating the gearbox lubrication design. A rotating gear test rig with an infrared pyrometer is developed in this paper to conduct real-time and accurate temperature measurements of the transverse plane of the oil-jet-lubrication herringbone gear.

Microstructure Evolution and Mechanical Properties of a Wire-Arc Additive Manufactured Austenitic Stainless Steel: Effect of Processing Parameter.

Two single track multi-layer walls with linear energy inputs (LEIs) of 219 and 590 J/mm were deposited by cold metal transfer-based wire arc additive manufacturing system. Combined with the X-ray diffraction technique, scanning electron microscope and uniaxial tensile tests, the influences of LEI and cooling rate (CR) on the microstructure evolution, mechanical properties and fracture mechanisms of the studied steel are analyzed. It is observed that the microstructures of the studied steel are mainly composed of δ-ferrite and austenite dendrites.

In Situ Investigation of Grain Evolution of 300M Steel in Isothermal Holding Process.

The relationships between initial microstructures, process parameters, and grain evolutions in isothermal holdings have drawn wide attention in recent years, but the grain growth behaviors of 300M steel were not well understood, resulting in a failure in precise microstructure controlling in heat treatment. In this work, in situ observations were carried out to characterize the grain evolutions of 300M steel with varying holding time, holding temperatures, and initial microstructures. The intriguing finding was that the grain refinement by austenization of 300M steel was followed by a dramatic grain growth in the initial stage of holding (≤~600 s), and with increasing time (~600⁻7200 s), the average grain size appeared to have a limit value at specific temperatures.

Effect of Die Geometry on the Formability of 5052 Aluminum Alloy in Electromagnetic Impaction Deformation.

The formability of aluminum alloy sheet in electromagnetic impaction deformation has attracted the attention of numerous researchers for the past decades. However, the influences of die geometry and high-speed impaction electromagnetic deformation on formability have not been well established, thereby resulting in the formability of the sheet not being developed fully. In this study, the influence of die geometry on the formability of 5052 aluminum alloy in electromagnetic deformation was investigated by comparing the formability of 5052 aluminum alloys formed using a hemispherical die and a cylindrical die.

Dislocation Based Flow Stress Model of 300M Steel in Isothermal Compression Process.

The relationship between microstructure and flow behaviour has attracted attention from many researchers for the past decades, whilst the influences of dislocation and recrystallization on flow stress have not been well understood, which led to failure in flow stress prediction at high temperature compressions. In this work, we tried to provide a novel explanation of the relationship between microstructure evolutions and flow behaviour, and the influence of dislocation and recrystallization on flow stress was investigated. A dislocation based flow stress model was proposed and applied for 300M steel at the strain rate of 0.

Synthesis and antibacterial activity of dihydro-1,2-oxazine and 2-pyrazoline oxazolidinones: novel analogs of linezolid.

The synthesis and antibacterial activity of oxazolidinones containing dihydro-1,2-oxazine and 2-pyrazoline ring systems are described. Linezolid analogs utilizing dihydro-1,2-oxazines as morpholine mimics were prepared utilizing a nitrosoamine/diene 4+2 cycloaddition strategy. Pyrazolidine, hexahydro-pyridazine, and 2-pyrazoline analogs more closely related to eperezolid were also prepared.