Publications by authors named "Zhiyun Zhan"

Background: Uveal melanoma (UVM) is a malignant intraocular tumor in adults. Targeting genes related to oxidative phosphorylation (OXPHOS) may play a role in anti-tumor therapy. However, the clinical significance of oxidative phosphorylation in UVM is unclear.

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Objective: To examine the role of transnasal endoscopic approaches in the management of intraconal tumors and demonstrate the use of an eyelid speculum in comparison with different techniques of medial rectus muscle (MRM) retraction.

Methods: Retrospective data of five patients with intraconal tumors operated on and followed up by the senior authors between December 2019 and April 2022 was collected. Presenting symptoms, technical details, imaging and histology findings, outcomes, and complications were evaluated.

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Synopsis of recent research by authors named "Zhiyun Zhan"

  • - Zhiyun Zhan's research primarily focuses on innovative approaches to diagnosing and treating ocular tumors, particularly uveal melanoma, highlighting the potential of oxidative phosphorylation-related gene targeting as a therapeutic strategy.
  • - A notable study involved the development of a prognostic risk score model for uveal melanoma, which aims to clarify the clinical significance of oxidative phosphorylation in the disease's treatment and management.
  • - In addition to uveal melanoma, Zhan has explored the use of advanced endoscopic techniques for managing intraconal tumors, providing insights from a retrospective study of patient outcomes and procedural evaluations.