Key role of suspended particulate matter in assessing fate and risk of endocrine disrupting compounds in a complex river-lake system.

Endocrine-disrupting compounds (EDCs) enter lakes mainly through river inflow. However, the occurrence, transport and fate of EDCs in the overlying water, suspended particulate matter (SPM) and sediment of inflowing rivers remain unclear. This study investigated the load of seven EDCs in a complex river-lake system of the Taihu Lake Basin during different seasons, with the aims of revealing the transport routes of EDCs and identifying the contributions from different sources.

Large-scale analyses of heat shock transcription factors and database construction based on whole-genome genes in horticultural and representative plants.

Heat shock transcription factor (Hsf) plays a critical role in regulating heat resistance. Here, 2950 Hsf family genes were identified from 111 horticultural and representative plants. More Hsf genes were detected in higher plants than lower plants.

Metallic Copper-Containing Composite Photocatalysts: Fundamental, Materials Design, and Photoredox Applications.

Semiconductor photocatalysis has long been regarded as a potential solution to tackle the energy and environmental challenges since the first discovery of water splitting by TiO almost 50 years ago. The past few years have seen a tremendous flurry of research interest in the modification of semiconductors because of their shortcomings in the aspects of solar harvesting, electron-hole pairs separation, and utilization of photogenerated carriers. Among the various strategies, the introduction of metallic copper into the photocatalysis system can not only enhance the absorption of sunlight and the separation efficiency of photogenerated electrons and holes, but also increase the adsorption ability of substrate and the number of active sites, so as to realize the high solar to chemical energy conversion efficiency.

[The application of carbohydrate binding module- cutinase fusion protein in polyethylene terephthalate degradation].

With the development of global economy, the dramatically increased production of polyethylene terephthalate (PET) plastics has led to a remarkably increased amount of plastic waste. PET waste can be treated by landfill, incineration, or biodegradation. While landfilling and incineration may cause secondary pollution, biodegradation has since received increased attentions due to its environmental friendliness.

Improvement of methanol tolerance and catalytic activity of Rhizomucor miehei lipase for one-step synthesis of biodiesel by semi-rational design.

Exploiting highly active and methanol-resistant lipase is of great significance for biodiesel production. A semi-rational directed evolution method combined with N-glycosylation is reported, and all mutants exhibiting higher catalytic activity and methanol tolerance than the wild type (WT). Mutant N267 retained 64% activity after incubation in 50% methanol for 8 h, which was 48% greater than that of WT.

Surface Passivation of MAPbBr Perovskite Single Crystals to Suppress Ion Migration and Enhance Photoelectronic Performance.

Recently, organometal halide perovskites (OHPs) have achieved significant advancement in photovoltaics, light-emitting diodes, X-ray detectors, and transistors. However, commercialization and practical applications were hindered by the notorious ion migration issue of OHPs. Here, we report a simple solvent-based surface passivation strategy with organic halide salts (methylammonium bromide (MABr) and phenylethylammonium bromide (PEABr)) to suppress the ion migration of MAPbBr single crystals.

Effect of Shengmai Yin on the DNA methylation status of nasopharyngeal carcinoma cell and its radioresistant strains.

Shengmai Yin (SMY) is a Chinese herbal decoction that effectively alleviates the side effects of radiotherapy in various cancers and helps achieve radiotherapy's clinical efficacy. In this study, we explored the interaction mechanism among SMY, DNA methylation, and nasopharyngeal carcinoma (NPC). We identified differences in DNA methylation levels in NPC CNE-2 cells and its radioresistant cells (CNE-2R) using the methylated DNA immunoprecipitation array and found that CNE-2R cells showed genome-wide changes in methylation status towards a state of hypomethylation.

Mechanism of the switch from NO to HO in endothelium-dependent vasodilation in diabetes.

Coronary microvascular dysfunction is prevalent among people with diabetes and is correlated with cardiac mortality. Compromised endothelial-dependent dilation (EDD) is an early event in the progression of diabetes, but its mechanisms remain incompletely understood. Nitric oxide (NO) is the major endothelium-dependent vasodilatory metabolite in the healthy coronary circulation, but this switches to hydrogen peroxide (HO) in coronary artery disease (CAD) patients.

Antibiotics along an alpine river and in the receiving lake with a catchment dominated by grazing husbandry.

The livestock breeding industries face overuse of antibiotics, which has been intensively studied in recent years. However, the occurrence and fate of antibiotics as well as their potential threats to the aquatic environments in alpine and arid regions remain unclear. This study investigated the relationship of the occurrence and concentrations of antibiotics between the Kaidu River and Bosten Lake in a typical alpine basin in China.

Closed-Cell Rigid Polyimide Foams for High-Temperature Applications: The Effect of Structure on Combined Properties.

Closed-cell rigid polyimide foams with excellent thermal stability and combined properties were prepared by thermal foaming of a reactive end-capped polyimide precursor powder in a closed mold. The precursor powder was obtained by thermal treatment of a polyester-amine salt (PEAS) solution derived from the reaction of the diethyl ester of 2,3,3',4'-biphenyl tetracarboxylic dianhydride (α-BPDE) with an aromatic diamine mixture of p-phenylenediamine (PDA) and 2-(4-aminophenyl)-5-aminobenzimidazole (BIA) in the presence of an end-capping agent (mono-ethyl ester of nadic acid anhydride, NE) in an aliphatic alcohol. The effect of polymer mainchain structures on the foaming processability and combined properties of the closed-cell rigid polyimide foams were systematically investigated.

Adverse event of Sinovac Coronavirus vaccine: Deafness.

COVID-19 has spread worldwide and is one of the most threatening infectious diseases in the world. Vaccination is known as an effective method to protect susceptible populations against such diseases. The Coronavirus vaccine developed by Sinovac has been shown to have a high protective effect, but it also has potential adverse events.

A Method for the Analysis of African Swine Fever by Viral Metagenomic Sequencing.

In 2018, there was an outbreak of African swine fever (ASF) in China, which spread to other provinces in the following 3 years and severely damaged China's pig industry. ASF is caused by the African swine fever virus (ASFV). Given that the genome of the African swine fever virus is very complex and whole genome information is currently inadequate, it is important to efficiently obtain virus genome sequences for genomic and epidemiological studies.

Covalent Pinning of Highly Dispersed Ultrathin Metallic-Phase Molybdenum Disulfide Nanosheets on the Inner Surface of Mesoporous Carbon Spheres for Durable and Rapid Sodium Storage.

Two-dimensional (2D) transition-metal dichalcogenide materials show potential for use in alkali metal ion batteries owing to their remarkable physical and chemical properties. Nevertheless, the electrochemical energy storage performance is still impaired by the tendency of aggregation, volume, and morphological change during the conversion reaction and poor intrinsic conductivity. Until now, ultrathin molybdenum disulfide nanosheets with a metallic-phase structure on the inner surface of mesoporous hollow carbon spheres (M-MoS@HCS) have rarely been investigated as an anode for sodium-ion batteries.

The Mediating Effect of Coping Style on Physical Activity and Negative Affect Caused by Public Health Emergencies: Evidence from Chinese College Students.

In this study, we explored the relationship between physical activity (PA), coping style (CS) and negative affect caused by public health emergencies (PHENA), to examine if CS can play a mediating role between PA and PHENA, and analyzed the different effects of positive coping (PC) and negative coping (NC). Using the method of random sampling, 700 students from four universities in Beijing and Shanghai were recruited to complete questionnaires about PA, CS and PHENA. Data collection was conducted through online and offline questionnaires.

High-Q, submicron-confined chalcogenide microring resonators.

We demonstrate high quality (Q) factor microring resonators in high index-contrast GeSbSe chalcogenide glass waveguides using electron-beam lithography followed by plasma dry etching. A microring resonator with a radius of 90 μm shows an intrinsic Q factor of 4.1 × 10 in the telecom band.

Recent advances of metal telluride anodes for high-performance lithium/sodium-ion batteries.

Metal tellurides (MTs) have emerged as highly promising candidate anode materials for state-of-the-art lithium-ion batteries (LIBs) and sodium ion batteries (SIBs). This is owing to the unique crystal structure, high intrinsic conductivity, and high trap density of such materials. The present work delivers a detailed discussion on the latest research and progress associated with the use of MTs for LIBs/SIBs with a focus on reaction mechanisms, challenges, electrochemical performance, and synthesis strategies.

circPhc3 sponging microRNA‑93‑3p is involved in the regulation of chondrocyte function by mechanical instability in osteoarthritis.

Cartilage extracellular matrix (ECM) metabolism disorder caused by mechanical instability is a leading cause of osteoarthritis (OA), but the exact mechanisms have not been fully elucidated. Recent studies have suggested an important role of circular RNAs (circRNAs/circs) in OA. The present study aimed to investigate whether circRNAs might have a role in mechanical instability‑regulated chondrocyte matrix metabolism in OA.

Ultrasound-guided Multiple Nerve Blocks: A Safe and Effective Anesthetic Modality in Geriatric Hip Fracture Patients.

Objectives: The aim was to compare the feasibility of ultrasound-guided multiple nerve blocks (fascia iliaca compartment block+sacral plexus block+superior cluneal nerve block) with general anesthesia in geriatric hip fracture patients.

Methods: Ninety-four patients were randomly divided into 2 groups: group N received ultrasound-guided multiple nerve blocks and group G received general anesthesia. Primary outcome measures included perioperative Pain Threshold Index (PTI) and Numerical Rating Scale.

Identification of diagnostic signatures in ulcerative colitis patients via bioinformatic analysis integrated with machine learning.

Ulcerative colitis (UC) is an immune-related disorder with enhanced prevalence globally. Early diagnosis is critical for the effective treatment of UC. However, it still lacks specific diagnostic signatures.

Rapamycin targets STAT3 and impacts c-Myc to suppress tumor growth.

Rapamycin is widely recognized as an inhibitor of mTOR, and has been approved for clinical use as an immunosuppressant. Its potencies in anti-cancer, anti-aging, and neurodegenerative diseases are emergingly established. The exploration of other targets of rapamycin will further elucidate its underlying mechanisms of action.

Ru@N/S/TiO/rGO: a high performance HER electrocatalyst prepared by dye-sensitization.

Hydrogen production from water-splitting is one of the most promising hydrogen production methods, and the preparation of the hydrogen evolution reaction (HER) catalyst is very important. Although Pt-based materials have the best catalytic activity for HER, their high price and scarcity greatly limit their large-scale industrial application prospects. Herein, a new method to prepare HER catalyst is described, where dyes used in dye-sensitized solar cells (DSSCs) were used as precursors.