Publications by authors named "Zhiyu Zhai"

To evaluate the prevalence of type 2 diabetes mellitus (T2DM) and hyperlipidemia in hypertensive patients in South China and assess the relationship between these comorbidities and blood pressure control to develop targeted strategies for hypertension management. Data from the 2020 Guangzhou National Basic Public Health Service Program were analyzed using Chi-square tests, t-tests, and logistic regression with R 4.1.

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Background: DNA methylation is associated with cardiovascular (CV) disease. However, in type 2 diabetes (T2D) patients, the role of gene methylation in the development of CV disease is under-studied. We aimed to identify the CV disease-related DNA methylation loci in patients with T2D and to explore the potential pathways underlying the development of CV disease using a two-stage design.

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Objective: To understand the prevalence of hypertension and hyperlipidaemia as well as the current status of glycaemic control and its influencing factors among type 2 diabetes mellitus patients in the community in South China, and to provide recommendations for the prevention and control of diabetes.

Methods: Questionnaires, physical examinations and laboratory tests were conducted on patients with type 2 diabetes mellitus who participated in the National Basic Public Health Service Programme in Guangzhou in 2020. The chi-square test, t-test and multi-factor unconditional logistic regression analysis were performed using R 4.

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Aims: This study investigated the association between serum calcium levels and the prevalence of T2D using a cross-sectional study and Mendelian randomization analysis.

Methods: Cross-sectional data were obtained from the National Health and Nutrition Examination Survey (NHANES) from 1999 to 2018. Serum calcium levels were divided into three groups (low, medium and high groups) according to the tertiles.

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Article Synopsis
  • The study analyzes changes in sleep patterns and the use of medications for insomnia among US adults from 2005 to 2018, utilizing data from nearly 40,000 participants.
  • Results reveal that while women reported more trouble sleeping and higher medication usage, men experienced shorter sleep duration and more sleep disorders, with an overall increase in trouble sleeping particularly noted in men.
  • Over the years, the percentage of adults experiencing insufficient sleep decreased, though the use of insomnia medications peaked in 2013-2014 before slightly declining.
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