Publications by authors named "Zhiyi Lei"
Article Synopsis
- The study aimed to compare cardiac autonomic function, structure, and diastolic function between individuals with diabetic foot (DF) and those with diabetes but without DF.
- A total of 850 participants (413 with DF and 437 without) underwent assessments using a 24-hour Holter electrocardiogram and Doppler echocardiogram for analyzing heart rate variability and cardiac function.
- Results indicated that individuals with DF had significantly poorer heart rate variability and distinct cardiac structural differences; however, many of these structural differences were not significant in the more refined analysis, suggesting impaired autonomic function is a key concern for those with DF.
Introduction: MRI has demonstrated its potential in the diagnosis of placenta percreta. Texture analysis is a novel technique to quantify tissue heterogeneity. The study aimed to evaluate the feasibility of using texture analysis based on myometrium-derived T2WI to differentiate placenta accreta from increta.
View Article and Find Full Text PDFThe Interaction of GLUT1 and FOXM1 Leads to a Poor Prognosis in Colorectal Cancer.
Anticancer Agents Med Chem
May 2021
Background: Colorectal Cancer (CRC) is one of the most common fatal diseases with high morbidity. Alteration of glucose metabolism is one of the hallmarks in the development of CRC. Glucose Transporter 1 (GLUT1) is a key rate-limiting protein in hyperactive glucose metabolism and up-regulated in CRC, however, the underlying mechanism of the altered metabolism in CRC is still unknown.
View Article and Find Full Text PDFNLRP3 Promotes Colorectal Cancer Cell Proliferation and Metastasis via Regulating Epithelial Mesenchymal Transformation.
Anticancer Agents Med Chem
May 2021
Background: Nucleotide-binding domain Leucine-rich Repeat Protein 3 (NLRP3) plays a regulatory role in the immune and inflammatory responses, and has been implicated in Colorectal Cancer (CRC) progression and metastasis. However, the underlying molecular mechanisms have not been fully elucidated.
Methods: In this study, we analyzed the expression levels of NLRP3 in human CRC tissues, and performed functional assays in CRC cell lines and a subcutaneous tumor model to elucidate its role in the development and progression of CRC.