Comput Intell Neurosci
April 2022
The instability of financial market will have a great impact on money, bonds, and stocks and affect the economic development of society and people's lives. Therefore, it is very necessary for us to study and predict the financial stability. According to the forecast results, we will analyze and make a series of preparatory measures.
View Article and Find Full Text PDFRealizing robust DNA functionalization with strict valence control in the sub-2-nm thiolate-protected luminescent gold nanoparticles (AuNPs) is highly demanded but remains unsolved due to their unique Au(0) core and Au(I)-S shell structures. Herein, we report a facile strategy using phosphorothioates (ps)-modified DNA (psDNA) as a template for growth of near-infrared (NIR)-emitting AuNPs with precisely controlled DNA valence. In addition, the particle size could be finely tuned in ultrasmall ranges from 1.
View Article and Find Full Text PDFThe simultaneous possession of high tumor-targeting efficiency, long blood circulation, and low normal-tissue retention is critical for future clinically translatable nanomedicines. Herein, we reported a facile in situ glycoconjugation strategy for the synthesis of near-infrared (NIR)-emitting gold glyconanoparticles (AuGNPs, ∼2.4 nm) using 1-thio-β-d-glucose as both the surface ligand and the reducing agent in the presence of a gold precursor.
View Article and Find Full Text PDFUltrasmall luminescent gold nanoparticles (AuNPs, d < 3.0 nm) with distinct optical properties and good biocompatibilities hold enormous promise for advanced disease theranostics. However, ultrasmall AuNPs generally show low cellular interaction and are hardly ever transported into the specific subcellular compartments, hampering their further biomedical use in cellular delivery and intracellular tracking.
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