Tuning Crystalline Preferred Orientation of SnSe Anode by Co-doping to Enhance Pseudocapacitive Behaviors for High-Performance Sodium Storage.

SnSe has attracted great attention due to its unique 2D-layered structure, which makes it capable of sodium ion storage and higher theoretical capacities compared to traditional anode materials like hard carbon for sodium ion batteries (SIBs). However, SnSe-based materials will cause structural damage due to volume expansion during ion storage, leading to poor cycle stability and rate capacity. In this work, Co-doped SnSe (Co-SnSe) with preferred crystal orientation was fabricated by a one-step solvothermal method.

Overexpression of mitochondrial histidyl-tRNA synthetase restores mitochondrial dysfunction caused by a deafness-associated tRNA mutation.

The deafness-associated m.12201T>C mutation affects the A5-U68 base-pairing within the acceptor stem of mitochondrial tRNA The primary defect in this mutation is an alteration in tRNA aminoacylation. Here, we further investigate the molecular mechanism of the deafness-associated tRNA 12201T>C mutation and test whether the overexpression of the human mitochondrial histidyl-tRNA synthetase gene () in cytoplasmic hybrid (cybrid) cells carrying the m.

LncRNA ZFAS1 promotes proliferation and migration and inhibits apoptosis in nasopharyngeal carcinoma via the PI3K/AKT pathway in vitro.

Background: Increasing evidence shows that long non-coding RNAs (lncRNAs) play a key role in the development of various cancers. Zinc finger antisense 1 (ZFAS1) is a novel lncRNA with previously demonstrated associations with several types of cancer. Here we examined the expression and potential function of the ZFAS1 in nasopharyngeal carcinoma (NPC).

Full-length spleen tyrosine kinase inhibits the invasion and metastasis of human laryngeal squamous cell carcinoma.

Objective: This study aimed to investigate correlation between full-length spleen tyrosine kinase [SYK (L)] expression and clinical characteristics of laryngeal squamous cell carcinoma (LSCC), and explore effects of SYK (L) on invasion and metastasis of LSCC.

Methods: The human laryngeal cancer Hep-2 cells with low SYK (L) expression were transfected with pIRES2-EGFP-SYK (L) vector and empty vector pIRES2-EGFP to generate Hep-2-SYK (L) cells and Hep-2-neo cells. The cell invasion and migration abilities were determined.

[The microsurgical anatomic research of the internal auditory canal area on the retrosigmold approach].

Objective: To evaluate the safety of the circular round window and discus anatomic landmarks of posterior wall of internal auditory canal by investigating the microscopic anatomy of internal auditory canal area of the retrosigmold approach, which can provide the anatomical basis for acoustic neutrinomas surgery.

Method: Fifteen adult cadaver heads (30 sides) fixed with formalin were used in the study. The retrosigmold approach operations were imitated to dissect the blood vessels and nerves in internal auditory canal area by opening round bony window and removing posterior wall of internal auditory canal.

[Inhibitory effect of full-length spleen tyrosine kinase on invasion and metastasis of human laryngeal squamous cells].

Objective: To study the effect of gene transfection of full length spleen tyrosine kinase (Syk (L)) on the biological behavior of malignant cancer cells.

Methods: Eukaryotic expression vector pIRES2-EGFP-Syk (L) was constrauted and sequenc. Laryngeal carcinoma cell line Hep-2 were transfected with pIRES2-EGFP-Syk (L) vectors or blank vectors.

Tunable microwave frequency performance of nanocomposite Co2MnSi/PZN-PT magnetoelectric coupling structure.

Nanocrystalline Co2MnSi Heusler alloy films were deposited on the PZN-PT substrates by a composition gradient sputtering method. It is revealed that this multiferroic heterostructure shows very strong magnetoelectric coupling, leading to continuously tunable microwave frequency characteristics by electric field. With the increase of electric field intensity from 0 to 6 kV/cm, the magnetic anisotropy field H(K) increases from 90 Oe to 182 Oe with an increment of 102%, corresponding to a ME coefficient of 15.

[The effect and mechanism of SU11248 on proliferation of nasopharyngeal carcinoma cell line CNE-2].

Objective: To investigate the effect of sunitinib malate (SU11284) on proliferation of nasopharyngeal carcinoma cell line CNE-2 and explore its mechanism.

Methods: Nasopharyngeal carcinoma cell line CNE-2 was treated with SU11248 in vitro, and the change in the proliferation of CNE-2 cell line was observed by MTT assay; Real-time fluorescence quantitative PCR (FQ-PCR) and Western blotting were used to detect the levels of P27(KIP1);, cyclin G1 mRNA and protein in CNE-2 cells after treated with 2.5 μg/mL SU11284 for different durations.

5-aza-CdR induces the demethylation of Syk promoter in nasopharyngeal carcinoma cell.

The present study employed 5-aza-2'-deoxycytidine (5-aza-CdR) to treat nasopharyngeal carcinoma cell line CNE-1, CNE-2 and non-cancerous human nasopharyngeal epithelial cell line NP-69 to understand the effects on spleen tyrosine kinase (Syk) gene promoter methylation. The results showed that the methylation level of Syk gene is negatively associated with the differentiation level of the cell lines, and the 5-aza-CdR treatment decreased the methylation level in nasopharyngeal carcinoma cell lines. Additionally, the drug sensitivity of low-differentiated cell line was significantly higher than the high-differentiated cell line.

The promoter methylation of the Syk gene in nasopharyngeal carcinoma cell lines.

The aim of this study was to investigate the mRNA and protein expression levels of the Syk gene as well as its promoter methylation in nasopharyngeal carcinoma (NPC) cell lines. The CNE-1 (highly differentiated), CNE-2 (poorly differentiated) and NP69 (non-cancerous human immortalized nasopharyngeal epithelial cells) cell lines were used in the present study. The MS-PCR, Q-RT-PCR and western blotting methods were used to examine the Syk gene promoter methylation levels and mRNA and protein expression in the three cell lines.

The expression of cyclin G in nasopharyngeal carcinoma and its significance.

To investigate the expression of cyclin G1, cyclin G2 in nasopharyngeal carcinoma (NPC) cell lines and its significance. The protein expression of cyclin G1, cyclin G2 in NPC cell lines of different differentiation degree (HNE2, CNE1) was detected by indirect immunofluorescence. The mRNA expression of cyclin G1, cyclin G2 in HNE2 and CNE1 was measured with RT-PCR.

Three-dimensional reconstruction of the optic canal-based on multislice helical CT: a comparison analysis with skull dissection of 40 postmortem cases.

Decompression operation of the optic canal via the nasal path under endoscope is widely used, but it is both a challenging and controversial method. Unsatisfactory results were largely associated with otolaryngologists' limited understanding of the real anatomical situations of the optic canal before operation. To provide otolaryngologists with the real situations and data preoperation, multislice helical CT was used to reconstruct the images of the optic canal.

[The value of induced hypotension in nasal endoscopic surgery].

Objective: To observe the value of induced hypotension in nasal endoscopic surgery with local anesthesia.

Method: Sixty Patients were randomly divided into two groups. Group I : induced hypotension group; Group II: control group.