Publications by authors named "Zhiyang Jia"

Article Synopsis
  • The study aimed to assess how effective and safe the RLRL treatment is in slowing the progression of high myopia in children aged 7 to 12 years with significant nearsightedness (≥ -6.00 D).
  • Conducted as a multicenter, randomized, and single-blind clinical trial, 202 children were divided into two groups: one receiving RLRL treatment plus standard spectacles, and the other receiving only standard spectacles over a 12-month period.
  • Results showed that the group receiving RLRL experienced a reduction in both axial length and spherical equivalent refraction, indicating less progression of myopia compared to the control group, along with some positive changes in choroidal and retinal thickness.
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Retinopathy of prematurity (ROP) is a retinopathy caused by abnormal proliferation of blood vessels in premature infants. It can lead to retinal detachment and, in severe cases, blindness, rendering ROP a critical condition. Advances in neonatal medicine have improved survival rates of low birth weight and low gestational age infants.

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Background: Late-onset capsule block syndrome (CBS) is a rare complication of cataract phacoemulsification and the implantation of a posterior chamber intraocular lens (PCIOL), which manifests six months to years after surgery. The hallmark of CBS is the formation of an opaque liquid substance between the implanted intraocular lens (IOL) and the posterior capsule. However, its pathogenesis remains unclear.

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Background: Calcium (Ca), potassium (K) and magnesium (Mg) may be involved in the occurrence and development of glaucoma by influencing the retinal oxidative stress and regulate blood pressure. However, epidemiological opinions on dietary intake of macroelement related to glaucoma are inconsistent. Herein, this study aims to explore the association between dietary Ca, K, and Mg consumption and glaucoma.

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Introduction: Primary angle-closure glaucoma (PACG) is a leading cause of irreversible blindness globally, and the number of patients with PACG rises every year. Yet, there is a lack of knowledge about the clinical characteristics, therapeutic options and profile of patients with PACG in China. Hence, we design the China Glaucoma Treatment Pattern Study Ⅰ-Primary Angle-Closure Glaucoma (Ch-GTPⅠ).

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Purpose: To investigate the relationship between the retinal thickness in different subfields and the volume of white matter hyperintensity (WMH), with the hope to provide new evidence for the potential association between the retina and the brain.

Methods: A total of 185 participants aged over 40 years were included in our study. Magnetic resonance imaging (MRI) was used to image the WMH, and WMH volume was quantitatively measured by a specific toolbox.

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Introduction: The aim of this study was to compare the macular retinal vessel density (VD) of diabetics with high myopia, diabetics without high myopia, and healthy controls.

Methods: This cross-sectional study recruited type 2 diabetic (T2D) people with no history of ocular treatment in our hospital. Thirty T2D people with high myopia (30 eyes) were included in group A, while 30 T2D people (30 eyes) without myopia were included in group B.

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Eggplant ( L.; 2n = 24) is one of the most important Solanaceae vegetables and is primarily cultivated in China (approximately 42% of world production) and India (approximately 39%). Thousand-grain weight (TGW) is an important trait that affects eggplant breeding cost and variety promotion.

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Article Synopsis
  • - Strabismus is a common eye condition in children where both eyes do not align properly, which can lead to issues like double vision and affect learning if not treated in time; it often requires surgical intervention due to genetic and neurological causes.
  • - Traditional surgery for strabismus often results in complications due to human error, while the emergence of microsurgical techniques has improved the precision and outcomes of these procedures.
  • - A study found that microsurgery for strabismus in children leads to shorter surgery times, less blood loss, fewer complications, and overall better results, with factors like age and preoperative conditions influencing recovery.
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Aim: The aim of this study was to investigate the relationship between levels of glycosylated hemoglobin (HbA1c) with meibomian gland dysfunction (MGD) in patients with type 2 diabetes mellitus (T2DM) and to further explore the related influencing factors.

Methods: Totally, 167 patients with T2DM and 68 non-diabetic subjects were selected. Further, T2DM patients were divided into 2 groups based on 7% HbA1c.

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The Covid-19 crisis has forced great societal changes, including forcing many to work from home (WFH) in an effort to limit the spread of the disease. The ability to work from home has long been considered a perk, but we have few estimates of how many jobs are actually possible to be performed from home. This paper proposes a method to estimate the share of these jobs.

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Background: To investigate the effects of 0.05% povidone-iodine (PI) irrigation on the ocular surface structure and bacterial survival rate in patients with cataract.

Methods: Ninety eyes of 90 patients with cataract were included.

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The aim of the present study was to assess the curative effect of combined phacoemulsification, 23-gauge pars plana vitrectomy with Brilliant blue G-assisted limiting membrane peeling and gas tamponade in patients with coexisting idiopathic macular hole (IMH) and age-associated cataract. A total of 21 consecutive patients (21 eyes) with coexisting IMH and age-associated cataract were enrolled in the study. All patients were treated by 23-gauge microincision vitrectomy with internal limiting membrane peeling, gas tamponade and combined phacoemulsification.

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Background: This study sought to report the outcomes of a combined cataract extraction, intraocular lens (IOL) insertion and micro-incision vitrectomy (MIVS) procedure for the treatment of Behcet uveitis.

Methods: This investigation involved the retrospective evaluation of a case series of patients with Behcet uveitis who underwent cataract extraction, IOL insertion and MIVS in a single surgical session at the same institution between January 2013 and November 2016. Outcome measures included visual acuity, inflammatory reaction, systemic anti-inflammatory medications, intraocular pressure (IOP) and complications.

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Context: Thymosin α1 (Tα1) is considered to be a promising immunomodulatory drug and could balance immunity and tolerance in immune tolerance and autoimmunity.

Objective: To explore the efficacy of Tα1 plus routine complex treatment in patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD).

Methods: Eighty-four AECOPD patients were enrolled and randomized into an experimental group and a control group.

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Objective: The objective of the present investigation was to investigate the role of integrin-linked kinase (ILK) in the gemcitabine-resistant lung cancer cell line A549 and explore the underlying mechanism.

Materials And Methods: Gemcitabine-resistant A549 (A549/GemR) cell line was established by pulse-exposed to moderate concentration of gemcitabine (Gem), and the drug resistant index was measured by MTT assay. Expression of ILK in A549/GemR cell line was detected by Western blot and real-time PCR.

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Article Synopsis
  • The study aimed to compare the effectiveness and side effects of two chemotherapy drugs, pemetrexed and docetaxel, for treating nonsmall-cell lung cancer (NSCLC) in patients who didn't respond to previous EGFR-TKI treatment.
  • In a randomized Phase 2 trial, patients received either pemetrexed or docetaxel, and the results showed no significant difference in disease control, response rates, or survival between the two groups.
  • However, docetaxel was linked to higher rates of side effects like nausea, myelosuppression, renal damage, and hair loss, suggesting that pemetrexed is a more tolerated and effective option for these patients.
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