Publications by authors named "Zhiyang Hou"

Article Synopsis
  • - The study investigates the alternative non-homologous end-joining (alt-NHEJ) pathway, highlighting its role in contributing to genetic instability due to repairs of complex DNA double-strand breaks (DSBs).
  • - Researchers developed a novel Escherichia coli reporter system to examine the mechanism of alternative end-joining (A-EJ) in response to DSBs created by different types of ionizing radiation.
  • - Findings suggest that the complexity of DSBs influences the choice of A-EJ for repair, with specific molecular patterns and homology levels near the breaks affecting the repair pathway used, increasing the understanding of DNA repair processes.
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  • * Scientists measured over 15,000 proteins in different parts of rice plants to understand which proteins are important for specific jobs in those parts.
  • * They found cool connections between rice and another plant, Arabidopsis, and discovered that some parts of the rice plant make different amounts of proteins, which helps scientists learn more about how proteins are controlled.
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  • - Repeat-mediated deletion (RMD) rearrangement causes genome instability by deleting sequences between repeated DNA segments, often triggered by DNA double-strand breaks (DSBs), and the complexity of DSBs can influence this process.
  • - Using a transgenic strain and particle irradiation (like protons and carbon), researchers found that RMD was enhanced by these irradiations, with a positive correlation to the linear energy transfer (LET) of the particles.
  • - The study indicates that RMD enhancement can be hindered by specific intermolecular homologous sequences and is further stimulated by λ-Red recombinase, providing insights into the repair mechanisms for complex DNA damage.
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To clarify the content characteristics of the main active components and mineral elements of Cynomorium songaricum under different habitat conditions, and further explore the relationship between the quality of C. songaricum and habitats, this study took C. songaricum from 25 different habitats in China as the research object, and measured the contents of 8 main active components and 12 mineral elements separately.

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