Publications by authors named "Zhixing Gong"
De novo biosynthesis of sakuranetin from glucose by engineered Saccharomyces cerevisiae.
Appl Microbiol Biotechnol
June 2023
Article Synopsis
- * Researchers developed a de novo biosynthesis pathway of sakuranetin using genetically engineered yeast (S. cerevisiae), achieving a yield of 4.28 mg/L initially, which was later boosted to 50.62 mg/L through metabolic engineering strategies.
- * This study marks the first successful attempt to synthesize sakuranetin directly from glucose in S. cerevisiae, with yields further increasing to 158.65 mg/L in larger bioreactor setups.