Identification and analysis of drought-responsive F-box genes in upland rice and involvement of OsFBX148 in ABA response and ROS accumulation.

Background: Upland rice varieties exhibit significant genetic diversity and broad environmental adaptability, making them ideal candidates for identifying consistently expressed stress-responsive genes. F-box proteins typically function as part of the SKP1-CUL1-F-box protein (SCF) ubiquitin ligase complexes to precisely regulate gene expression and protein level, playing essential roles in the modulation of abiotic stress responses. Therefore, utilizing upland rice varieties for screening stress-responsive F-box genes is a highly advantageous approach.

Positive Association of TEAD1 With Schizophrenia in a Northeast Chinese Han Population.

Objective: Schizophrenia is a complex and devastating psychiatric disorder with a strong genetic background. However, much uncertainty still exists about the role of genetic susceptibility in the pathophysiology of schizophrenia. TEA domain transcription factor 1 (TEAD1) is a transcription factor associated with neurodevelopment and has modulating effects on various nervous system diseases.

Schizophrenia in the genetic era: a review from development history, clinical features and genomic research approaches to insights of susceptibility genes.

Schizophrenia is a devastating neuropsychiatric disorder affecting 1% of the world population and ranks as one of the disorders providing the most severe burden for society. Schizophrenia etiology remains obscure involving multi-risk factors, such as genetic, environmental, nutritional, and developmental factors. Complex interactions of genetic and environmental factors have been implicated in the etiology of schizophrenia.

Hydrogen sulfide alleviates osmotic stress-induced root growth inhibition by promoting auxin homeostasis.

Hydrogen sulfide (H S) promotes plant tolerance against various environmental cues, and d-cysteine desulfhydrase (DCD) is an enzymatic source of H S to enhance abiotic stress resistance. However, the role of DCD-mediated H S production in root growth under abiotic stress remains to be further elucidated. Here, we report that DCD-mediated H S production alleviates osmotic stress-mediated root growth inhibition by promoting auxin homeostasis.

Anticancer and antibacterial flavonoids from the callus of ; a new weapon to mitigate the proliferation of cancer cells and bacteria.

A new flavonoid angelioue (1) together with five known compounds cuminatanol (2), myricetin (3), epigallocatechin (4), taxifolin (5) and dihydromyricetin (6) was isolated from the callus extract of (Hand.-Mazz.) W.

The role of pregnane X receptor (PXR) in substance metabolism.

As a member of the nuclear receptor (NR) superfamily, pregnane X receptor (PXR; NR1I2) is a ligand-activated transcription factor that plays a crucial role in the metabolism of xenobiotics and endobiotics in mammals. The tissue distribution of PXR is parallel to its function with high expression in the liver and small intestine and moderate expression in the kidney, stomach, skin, and blood-brain barrier, which are organs and tissues in frequent contact with xenobiotics. PXR was first recognized as an exogenous substance receptor regulating metabolizing enzymes and transporters and functioning in detoxification and drug metabolism in the liver.

PIN3-mediated auxin transport contributes to blue light-induced adventitious root formation in Arabidopsis.

Adventitious rooting is a heritable quantitative trait that is influenced by multiple endogenous and exogenous factors in plants, and one important environmental factor required for efficient adventitious root formation is light signaling. However, the physiological significance and molecular mechanism of light underlying adventitious root formation are still largely unexplored. Here, we report that blue light-induced adventitious root formation is regulated by PIN-FORMED3 (PIN3)-mediated auxin transport in Arabidopsis.

Osmotic stress represses root growth by modulating the transcriptional regulation of PIN-FORMED3.

Osmotic stress influences root system architecture, and polar auxin transport (PAT) is well established to regulate root growth and development. However, how PAT responds to osmotic stress at the molecular level remains poorly understood. In this study, we explored whether and how the auxin efflux carrier PIN-FORMED3 (PIN3) participates in osmotic stress-induced root growth inhibition in Arabidopsis (Arabidopsis thaliana).

Methane Control of Adventitious Rooting Requires γ-Glutamyl Cysteine Synthetase-Mediated Glutathione Homeostasis.

Although the key role of methane (CH4) in the induction of cucumber adventitious rooting has been observed previously, the target molecules downstream of the CH4 action are yet to be fully elucidated. Here, we reported that exogenous glutathione (GSH) induced cucumber adventitious root formation; while l-buthionine-sulfoximine (BSO) treatment inhibited it. BSO is a known inhibitor of γ-glutamyl cysteine synthetase (γ-ECS), an enzyme involved in GSH biosynthesis.

Hydrogen sulfide acts downstream of methane to induce cucumber adventitious root development.

Previous results have shown that hydrogen sulfide (HS), mainly catalyzed by l-cysteine desulfhydrase (DES) in plants, triggers adventitious rooting. The objective of this study was to test whether HS is involved in methane (CH)-induced adventitious root development in cucumber explants. First, we observed that the activities of DES, endogenous HS production, and thereafter adventitious root development were induced by CH and NaHS (an HS donor).

Nitric oxide is involved in methane-induced adventitious root formation in cucumber.

Our previous studies revealed that methane (CH ) induces adventitious rooting in cucumber. However, the corresponding molecular mechanism is still elusive. In this work, we discovered that CH triggered the accumulation of nitric oxide (NO) and thereafter cucumber adventitious rooting, mimicking the inducing effects of sodium nitroprusside (SNP) and NONOate (two NO-releasing compounds).