Ran GTPase activating protein 1 (RanGAP1) has been implicated in various diseases, but its role in colorectal cancer (CRC) progression remains unclear. Using tumor tissues and public databases, we found that RanGAP1 was significantly upregulated in CRC tissues and was associated with poor prognosis of patients. N6-methyladenosine (m6A) was found to play an important role in higher expression of RanGAP1.
View Article and Find Full Text PDFSalinity is one of the most important abiotic stresses threatening plant growth and agricultural productivity worldwide. In green alga , physiological evidence indicates that saline stress increases intracellular peroxide levels and inhibits photosynthetic-electron flow. However, understanding the genetic underpinnings of salt-responding traits in plantae remains a daunting challenge.
View Article and Find Full Text PDFBackground: To analyze the clinicopathologic factors associated with mucosal and submucosal infiltration in differentiated depressed early gastric cancer, and screening factors that can predict depth of infiltration before endoscopic treatment.
Methods: The study included 35 cases of mucosal carcinomas and 66 cases of submucosal carcinomas according to the pathological diagnosis. The relevant clinicopathologic factors were investigated by univariate and multivariate analysis.
We show that in order to calculate correctly the spin current carried by a quasiparticle in an electron liquid one must use an effective "spin mass" m(s) that is larger than both the band mass m(b), which determines the charge current, and the quasiparticle effective mass m(*), which determines the heat capacity. We present two independent estimates of the spin mass enhancement, m(s)/m(b), in two- and three-dimensional electron liquids, based on (i) previously calculated values of the Landau parameters and (ii) a recent theory of the dynamical local field factor in the spin channel. Both methods yield a significant spin mass enhancement, which is larger in two dimensions than in three.
View Article and Find Full Text PDFWe derive the spin-wave dynamics of a magnetic material from the time-dependent spin-density-functional theory in the linear response regime. The equation of motion for the magnetization includes, besides the static spin stiffness, a "Berry curvature" correction and a damping term. A gradient expansion scheme based on the homogeneous spin-polarized electron gas is proposed for the latter two quantities, and the first few coefficients of the expansion are calculated to second order in the Coulomb interaction.
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