Assessing the influence of green space morphological spatial pattern on urban waterlogging: A case study of a highly-urbanized city.

The extensive expansion of impervious surfaces encroaches on green spaces and causes frequent urban waterlogging disasters. Previous studies have focused mainly on the influence of green space landscape pattern on waterlogging, with less attention given to green space morphological spatial pattern (MSPA). MSPA can be used to differentiate various types of land use morphologies from a microscopic perspective and reveal visualized spatial characteristics.

Experimental investigation on heat and moisture transfer of propylene glycol-mixed steam in porous media.

Propylene glycol (PG)-mixed steam enhanced extraction is a promising remediation technique for removing semi-volatile organic compounds (SVOCs) from the unsaturated zone. However, the mechanisms of heat and moisture transfer during PG-mixed steam injection remain unclear. In this study, a 2D experimental system was developed to enable non-invasive monitoring of the spatio-temporal distribution of temperature and degree of saturation during steam injection into porous media.

Investigating the Mechanism of Rare-Earth Ion Incorporation into Glass-Ceramic Crystal Phases through Er Ion Probe Characteristics.

Exploring the intrinsic mechanisms of rare-earth ions entering the crystal phase has great significance for finely tuning the luminescent properties of glass-ceramics. Using Er ions as a probe, X-ray diffraction was employed to precisely measure the crystallinity of SiO-PbF-ErO glass-ceramics synthesized under various heat treatment conditions, confirming the occurrence of a rapid crystallization process. Additionally, by combining Judd-Ofelt theory with comprehensive analyses of absorption and fluorescence spectra, we calculated the relative proportions of Er ions present in the crystal phase.

An Experimental Study on the Thermal Performance of a Heat Sink Filled with Porous Aluminum Skeleton/Paraffin Composite Phase Change Material.

Organic phase change material is an ideal solution to solve the heat dissipation problem of electronic devices. However, its low thermal conductivity limits its application. To solve this problem, a new porous aluminum skeleton/paraffin composite phase change material (AS-PCM) was prepared.

Hepatitis B virus X protein differentially regulates the angiogenesis of Hepatocellular Carcinoma through p53-VEGF axis according to glucose levels.

Introduction And Objectives: Blood glucose fluctuates severely in the diabetes (DM) and tumor microenvironment. Our previous works have found Hepatitis B virus X protein (HBx) differentially regulated metastasis and apoptosis of hepatoma cells depending on glucose concentration. We here aimed to explore whether HBx played dual roles in the angiogenesis of hepatocellular carcinoma varying on different glucose levels.

Enhancing CO Tolerance in PEMFC Anodes via Thermal Oxidation Induced RuO Blocking Shell on a PtRu/C Catalyst.

CO poisoning in Pt-based anode catalysts significantly hampers the proton exchange membrane fuel cell (PEMFC) performance. Despite great advances in CO-tolerant catalysts, their effectiveness is often limited to fundamental three-electrode systems, which is inadequate for practical PEMFC applications. Herein, we present a straightforward thermal oxidation strategy for constructing a Ru oxide blocking layer on commercial PtRu/C through a one-step Ru-segregation-and-oxidation process.

In-Plane Compression Properties of Continuous Carbon-Fiber-Reinforced Composite Hybrid Lattice Structures by Additive Manufacturing.

Continuous-fiber-reinforced composite lattice structures (CFRCLSs) have garnered attention due to their lightweight and high-strength characteristics. Over the past two decades, many different topological structures including triangular, square, hexagonal, and circular units were investigated, and the basic mechanical responses of honeycomb structures under various load conditions, including tension, compression, buckling, shear, and fatigue were studied. To further improve the performance of the honeycombs, appropriate optimizations were also carried out.

Experimental and Numerical Investigations on Thermal-Hydraulic Performance of Three-Dimensional Overall Jagged Internal Finned Tubes.

To satisfy the demand for efficient heat transfer, a novel three-dimensional overall jagged internal finned tube (3D-OJIFT) was fabricated, using the rolling-ploughing/extruding method. The thermal performance of the 3D-OJIFT were studied and compared in experiments and three-dimensional numerical simulations. The RNG - turbulence model is well verified with the experimental results.

Simultaneous Photocatalytic Tetracycline Oxidation and Cr(VI) Reduction by Z-Scheme Multiple Layer TiO/SnInS.

Wastewater pollutants are a major threat to natural resources, with antibiotics and heavy metals being common water contaminants. By harnessing clean, renewable solar energy, photocatalysis facilitates the synergistic removal of heavy metals and antibiotics. In this paper, MXene was both a template and raw material, and MXene-derived oxide (TiO) and SnInS Z-scheme composite materials were synthesized and characterized.

Activation of the FOXM1/ASF1B/PRDX3 axis confers hyperproliferative and antioxidative stress reactivity to gastric cancer.

Nucleosome assembly during DNA replication is dependent on histone chaperones. Recent studies suggest that dysregulated histone chaperones contribute to cancer progression, including gastric cancer (GC). Further studies are required to explore the prognostic and therapeutic implications of histone chaperones and their mechanisms of action in GC progression.

Quantum interference enhances the performance of single-molecule transistors.

Quantum effects in nanoscale electronic devices promise to lead to new types of functionality not achievable using classical electronic components. However, quantum behaviour also presents an unresolved challenge facing electronics at the few-nanometre scale: resistive channels start leaking owing to quantum tunnelling. This affects the performance of nanoscale transistors, with direct source-drain tunnelling degrading switching ratios and subthreshold swings, and ultimately limiting operating frequency due to increased static power dissipation.

A fusion protein of vimentin with Fc fragment inhibits Japanese encephalitis virus replication.

Japanese encephalitis virus (JEV), a member of the Flaviviridae family and a flavivirus, is known to induce acute encephalitis. Vimentin protein has been identified as a potential receptor for JEV, engaging in interactions with the viral membrane protein. The Fc fragment, an integral constituent of immunoglobulins, plays a crucial role in antigen recognition by dendritic cells (DCs) or phagocytes, leading to subsequent antigen presentation, cytotoxicity, or phagocytosis.

Connections to the Electrodes Control the Transport Mechanism in Single-Molecule Transistors.

When designing a molecular electronic device for a specific function, it is necessary to control whether the charge-transport mechanism is phase-coherent transmission or particle-like hopping. Here we report a systematic study of charge transport through single zinc-porphyrin molecules embedded in graphene nanogaps to form transistors, and show that the transport mechanism depends on the chemistry of the molecule-electrode interfaces. We show that van der Waals interactions between molecular anchoring groups and graphene yield transport characteristic of Coulomb blockade with incoherent sequential hopping, whereas covalent molecule-electrode amide bonds give intermediately or strongly coupled single-molecule devices that display coherent transmission.

In Situ Piezoelectric-Catalytic Anti-Inflammation Promotes the Rehabilitation of Acute Spinal Cord Injury in Synergy.

Relieving inflammation via scavenging toxic reactive oxygen species (ROS) during the acute phase of spinal cord injury (SCI) proves to be an effective strategy to mitigate secondary spinal cord injury and improve recovery of motor function. However, commonly used corticosteroid anti-inflammatory drugs show adverse side effects which may induce increased risk of wound infection. Fortunately, hydrogen (H), featuring selective antioxidant performance, easy penetrability, and excellent biosafety, is being extensively investigated as a potential anti-inflammatory therapeutic gas for the treatment of SCI.

Global, regional, and national burden of gallbladder and biliary diseases from 1990 to 2019.

Background: Gallbladder and biliary diseases (GABDs) are a major public health issue.

Aim: To analysis the cause-specific incidence, prevalence, and years lived with disability (YLDs) and its temporal trends of GABDs at the global, regional, and national level. Data on GABD were available from the Global Burden of Disease study 2019.

Interleukin-10 gene intervention ameliorates liver fibrosis by enhancing the immune function of natural killer cells in liver tissue.

Background And Aims: Interleukin 10 (IL-10) and natural killer (NK) cells have the potential to combat liver fibrosis. However, whether NK cells play an important role in the anti-fibrotic effects of IL-10 is not sufficiently elucidated. In this study, we investigated the regulatory effects of IL-10 on NK cells during liver fibrosis.

Resolvin D1 promotes the resolution of inflammation in the ACLF rat model by increasing the proportion of Treg cells.

Objective: Acute-on-chronic liver failure (ACLF) causes organ system failures in patients and increases the risk of mortality. One of the main predictors of ACLF development in patients is the severity of systemic inflammation. The purpose of this study was to explore the effects of resolvin D1 (RvD1) on the rat model of ACLF.

Hydrogenated silicene nanosheet functionalized scaffold enables immuno-bone remodeling.

An ideal implant needs to have the ability to coordinate the foreign body response and tissue regeneration. Here, Hydrogenated-silicon nanosheets (H-Si NSs) with favorable biodegradability are integrated and functionalized into a β-tricalcium phosphate scaffold (H-Si TCP) for bone defect healing. H-Si TCP can greatly improve bone regeneration through osteoimmunomodulation-guided biodegradation in vivo.

Cobalt coordinated carbon quantum dots boosting the performance of NiCo-LDH for energy storage.

Transition metal layered double hydroxides have extremely high specific capacitances but suffer from poor rate performance and cycling stability due to their low conductivity and structural stability. In this study, cobalt-coordinated carbon quantum dots (CoCQDs) were designed and synthesized to enhance the energy storage performance of nickel-cobalt layered double hydroxides (NiCo-LDH). Nickel and cobalt ions were co-electrodeposited with the CoCQDs to form a NiCo-LDH based composite electrode (denoted as CoC@LDH).

Mesenchymal Stem Cell-Derived Exosomes: A Novel Approach to Diabetes-Associated Cognitive Impairment.

The progression of diabetes frequently results in a myriad of neurological disorders, including ischemic stroke, depression, blood-brain barrier impairment, and cognitive dysfunction. Notably, diabetes-associated cognitive impairment, a prevalent comorbidity during the course of diabetes, progressively affects patients' cognitive abilities and may reciprocally influence diabetes management, thereby severely impacting patients' quality of life. Extracellular vesicles, particularly nanoscale exosomes, have garnered considerable attention in recent years.

USP5 promotes lipopolysaccharide-induced apoptosis and inflammatory response by stabilizing the TXNIP protein.

Background: The role of thioredoxin-interacting protein (TXNIP) in lipopolysaccharide-induced liver injury in mice has been reported, but the underlying mechanisms are poorly understood.

Methods: We overexpressed deubiquitinase in cells overexpressing TXNIP and then detected the level of TXNIP to screen out the deubiquitinase regulating TXNIP; the interaction between TXNIP and deubiquitinase was verified by coimmunoprecipitation. After knockdown of a deubiquitinase and overexpression of TXNIP in Huh7 and HepG2 cells, lipopolysaccharide was used to establish a cellular inflammatory model to explore the role of deubiquitinase and TXNIP in hepatocyte inflammation.

Phase-Coherent Charge Transport through a Porphyrin Nanoribbon.

Since the early days of quantum mechanics, it has been known that electrons behave simultaneously as particles and waves, and now quantum electronic devices can harness this duality. When devices are shrunk to the molecular scale, it is unclear under what conditions does electron transmission remain phase-coherent, as molecules are usually treated as either scattering or redox centers, without considering the wave-particle duality of the charge carrier. Here, we demonstrate that electron transmission remains phase-coherent in molecular porphyrin nanoribbons connected to graphene electrodes.