Synthesis and Properties of Thermostable Energetic Benzotriazines.

In an effort to balance energy and molecular stability effectively, several energetic compounds (-) based on benzotriazine were designed and synthesized. These structures were comprehensively characterized using NMR, IR, and elemental analysis, with compounds , , and further confirmed by single-crystal X-ray diffraction. Notably, 3-amino-5,7-dinitrobenzo[][1,2,4]triazine 1-oxide (), which features a face-to-face crystal stacking arrangement, exhibits good detonation velocity ( = 8050 m/s), a high thermal decomposition temperature ( = 290 °C), and low sensitivities (impact sensitivity >40 J, friction sensitivity >360 N).

Taxonomy and phylogeny of rodents parasitic fleas in southeastern China with description of a new subspecies of Ctenophthalmus breviprojiciens.

Accurate differentiation and identification of flea species are essential for both basic and applied research on fleas, as well as for the diagnosis of flea-borne diseases. However, distinguishing between flea species can be challenging, especially among those with minimal morphological differences. Therefore, some scholars have suggested the necessity of comprehensive revisions to the classification of fleas, incorporating morphological, molecular, and phylogenetic data.

Comparative analysis of the epidemiological characteristics of adenovirus, rotavirus A, and coinfection in children during 2014-2023 in Guangzhou, China.

Background: Infection is the cause of diarrhoea, and rotaviruses and adenoviruses are important pathogens in children.

Methods: A retrospective study was conducted on 144,067 children with diarrhoea between 2014 and 2023 in China. We used the colloidal gold method to detect intestinal adenovirus and rotavirus A antigens in faeces.

Effectiveness and safety study of formula containing probiotics, prebiotics, synbiotics on fullterm infants' growth - a systematic review and meta-analysis of randomized controlled study.

Background And Objective: Probiotics, prebiotics, and synbiotics, are hot topics of research and have been shown to improve the body's disease state and promote health. Analysis of whether infant formula containing probiotcs, prebiotics, synbiotics is beneficial to infant and child growth.

Methods: We systematically searched multiple electronic databases (PubMed, Web of Science, The Cochrane Library, Embase) to identify eligible studies published from 1966 to December 25, 2022.

Hybrid Biatrial Ablation Versus Catheter Ablation for Patients With Nonparoxysmal Atrial Fibrillation and Enlarged Left Atrium.

Objective: There is no consensus on the optimal ablation strategy for nonparoxysmal atrial fibrillation (NPAF) with enlarged left atrium. We aimed to explore whether hybrid ablation (HA) of combined thoracoscopic surgical ablation with catheter ablation (CA) was superior to CA alone in these patients.

Methods: Patients with NPAF and left atrial diameter (LAD) ≥45 mm who underwent hybrid biatrial ablation or CA procedure from June 2014 to July 2021 were included in this study.

Bifunctional Nitrogen-Rich Heterocyclic Compounds: Synthesis, Photoluminescence and Energetic Properties.

Nitrogen-rich heterocyclic frameworks have attracted enormous interest in organic chemistry and materials science. However, their potential for developing photoluminescent materials remains underexplored due to their relatively low molecular stabilities. In this work, two tricyclic fused nitrogen-rich fluorescent heterocycles were synthesized and characterized.

Changing ozone sensitivity in Fujian Province, China, during 2012-2021: Importance of controlling VOC emissions.

In the troposphere, ozone (O) formation can be limited by NOx, VOCs, or both, complicating efforts to reduce O by controlling its precursors. This study used formaldehyde (HCHO) data and nitrogen dioxide (NO) data from the Ozone Monitoring Instrument (OMI) to analyze O formation sensitivity in Fujian from 2012 to 2021. Over the past decade, an 8.

Pore Size Distribution and Fractal Characteristics of Deep Coal in the Daning-Jixian Block on the Eastern Margin of the Ordos Basin.

Important breakthroughs have recently been achieved in deep coalbed methane (CBM) exploration and development in regions such as the eastern margin of the Ordos Basin, China. Investigating the development characteristics of various-scale pores in deep coalbeds is of great significance for resource assessment and selection of favorable zones for CBM exploration. Herein, six deep coal samples were selected from the Shanxi and Taiyuan Formations in the Daning-Jixian block on the eastern margin of the Ordos Basin.

Suppression of RCAN1 alleviated lipid accumulation and mitochondrial fission in diabetic cardiomyopathy.

Background: Although metabolic disturbance is a characteristic of diabetic cardiomyopathy (DbCM), the detailed pathogenesis of DbCM remains unknown.

Methods: We used a heart transplantation (HTx) cohort to explore the effect of diabetes mellitus on heart failure (HF) progression dependent of myocardium. Microscopic and ultramicroscopic pathology were used to depict the pathological features of human myocardium of DbCM.

Microcin Y utilizes its stable structure and biological activity to regulate the metabolism of intestinal probiotics and effectively clear gut Salmonella.

MccY is a novel, structurally stable microcin with antibacterial activity against Enterobacteriaceae. However, the bioavailability of orally administrated MccY is unknown. This study evaluated the effects of MccY as a antimicrobial on pre-digestion in vitro and its intake, digestion and gut metabolism in vivo.

Diazotization of -Aminoamidoximes for the Preparation of Energetic 6,5,6-Fused 1,2,3-Triazine-3-oxides.

Two 6,5,6-fused 1,2,3-triazine-3-oxides ( and ) were designed and synthesized via the reaction of -aminoamidoximes with sodium nitrite. In addition, the ring-opening products (, , and ) derived from 1,2,3-triazine-3-oxides were isolated and characterized. A comprehensive exploration of the reaction mechanism governing the ring-opening process was performed through a combination of theoretical and experimental studies.

Effect of oral administration of microcin Y on growth performance, intestinal barrier function and gut microbiota of chicks challenged with Salmonella Pullorum.

The lasso peptide microcin Y (MccY) effectively inhibits various serotypes of Salmonella in vitro, but the antibacterial effect against S. Pullorum in poultry is still unclear. This study was the first to evaluate the safety and anti-S.

Nondestructive Assessment of Quality Characteristics of As-Built Additive Manufacturing Aeronautical AlSi10Mg and Inspection of Offset.

AlSi10Mg is widely used in additively manufacturing aeronautical lattice and honeycomb structures. The unclear complex quality characteristics has been an obstacle of nondestructive testing of additive manufacturing (AM) AlSi10Mg, especially at its as-built state. This article attempts to reveal the quality characteristics of as-built AM aeronautical AlSi10Mg based on its conductivity characteristics.

A new score for predicting intracranial hemorrhage in patients using antiplatelet drugs.

Antiplatelet drugs in patients increase the risk of intracranial hemorrhage (ICH), which can seriously affect patients' quality of life and even endanger their lives. Currently, there is no specific score for predicting the risk of ICH caused by antiplatelet drugs. We aimed to identify factors associated with ICH in patients on antiplatelet drugs and to construct and validate a predictive model that would provide a validated tool for the clinic.

Structural identification and anti-neuroinflammatory effect of a heteropolysaccharide ATP50-3 from Acorus tatarinowii rhizome.

Acorus tatarinowii, a famous traditional Chinese medicine, is used for the clinical treatment of memory impairment and dementia. In this research, AT50, the crude polysaccharide extracted from A. tatarinowii rhizome, significantly improved the memory and learning ability of mice with Alzheimer's disease (AD) and exerted excellent anti-neuroinflammatory effects.

Microcage flame retardants with complete recyclability and durability reversible interfacial locking engineering.

Flame retardants are effective in protecting materials from fire but pose environmental challenges due to limited recyclability. Urgently needed for circular material economy are new flame retardants that are chemically recyclable and durable. Here, we report a new facile and scalable strategy for engineering reversible microcages with infinite chemical recyclability to starting monomers, exceptional durability, and versatile flame retardancy.

Investigating the efficacy and importance of mobile-based assessments for Parkinson's disease: uncovering the potential of novel digital tests.

This study introduces PDMotion, a mobile application comprising 11 digital tests, including those adapted from the MDS-Unified Parkinson's Disease Rating Scale (MDS-UPDRS) Part III and novel assessments, for remote Parkinson's Disease (PD) motor symptoms evaluation. Employing machine learning techniques on data from 50 PD patients and 29 healthy controls, PDMotion achieves accuracies of 0.878 for PD status prediction and 0.

Risk factors for anticoagulant-associated gastrointestinal hemorrhage: a systematic review and meta-analysis.

Background/aims: There may be many predictors of anticoagulation-related gastrointestinal bleeding (GIB), but until now, systematic reviews and assessments of the certainty of the evidence have not been published. We conducted a systematic review to identify all risk factors for anticoagulant-associated GIB to inform risk prediction in the management of anticoagulation- related GIB.

Methods: A systematic review and meta-analysis were conducted to search PubMed, EMBASE, Web of Science, and Cochrane Library databases (from inception through January 21, 2022) using the following search terms: anticoagulants, heparin, warfarin, dabigatran, rivaroxaban, apixaban, DOACs, gastrointestinal hemorrhage, risk factors.

Characteristics and Influence Factors of Natural Desorption in Coal Bodies from Fukang Mining Area, Xinjiang, China.

Coal body desorption characteristics are one of the key factors that influence the development of coalbed methane (CBM). In this study, 91 coal core samples from 11 CBM wells in the Fukang mining area were collected from Xinjiang, China, and the coal quality, high-pressure mercury compression, gas content, and natural desorption characteristics measurements were launched. With the detailed analyses of the differences in cumulative desorption volume, desorption ratio, and on-site average desorption rate for the coal samples with different body structures and macrolithotypes, the influence of the maximum reflectance of vitrinite, microscopic coal rock composition, and coal quality and pore characteristics on CBM desorption characteristics were discussed.

Size measurement and filled/unfilled detection of rice grains using backlight image processing.

Measurements of rice physical traits, such as length, width, and percentage of filled/unfilled grains, are essential steps of rice breeding. A new approach for measuring the physical traits of rice grains for breeding purposes was presented in this study, utilizing image processing techniques. Backlight photography was used to capture a grayscale image of a group of rice grains, which was then analyzed using a clustering algorithm to differentiate between filled and unfilled grains based on their grayscale values.