Publications by authors named "Zhitong Lin"
Article Synopsis
- - Small-molecule inhibitors targeting the MDM2/p53 interaction help stabilize p53, presenting a potential approach for cancer therapy.
- - Two specific compounds, TB114 (2) and another identified as 22, were found to effectively inhibit MDM2/p53 interactions and demonstrated strong anti-cancer effects in cell lines with wild-type p53.
- - Mechanistic studies revealed that these compounds activate p53, induce apoptosis, and are non-toxic to certain normal cells, suggesting they could be developed into a promising treatment for cancers with wild-type p53.
The synergistic effects of the combination of acetylated distarch adipate and sesbania gum (C-ADA-SG) with the ratio of 5:0, 4:1, 2.5:2.5, 1:4, 0:5, accounting for 5% (w/w) of the starch on gelatinization and retrogradation properties of wheat starch (WS) were studied.
View Article and Find Full Text PDF