Moniezia benedeni drives the SNAP-25 expression of the enteric nerves in sheep's small intestine.

Background: The neuroimmune network plays a crucial role in regulating mucosal immune homeostasis within the digestive tract. Synaptosome-associated protein 25 (SNAP-25) is a presynaptic membrane-binding protein that activates ILC2s, initiating the host's anti-parasitic immune response.

Methods: To investigate the effect of Moniezia benedeni (M.