Publications by authors named "Zhiran Zhou"
Article Synopsis
- Polysaccharides (PSY) have various beneficial properties but are not commonly used in food, prompting this study to explore their potential using parts of a Southeast Asian plant.
- The research focused on creating complexes with whey protein concentrate (WPC) from the plant's stem (HCPS) and leaf (HCPL), measuring their stability and antioxidant activities.
- Results indicated that the HCPL-WPC complex displayed greater stability and better antioxidant activity compared to the HCPS-WPC complex, highlighting possibilities for using polysaccharides in food applications.
Article Synopsis
- The study focused on extracting water-soluble natural polysaccharides from Thunb stems using an optimized hot water extraction process, achieving a maximum yield of 2.43%.
- The structural analysis of the extracted polysaccharides revealed a dominant composition of various sugars, with an average molecular weight of approximately 8.854 × 10^3 kDa and specific chemical backbones.
- The extracted polysaccharides demonstrated significant antioxidant activity and inhibited enzymes related to carbohydrate digestion, indicating potential applications for managing blood sugar levels and enhancing food products.
MAPK signaling pathway-targeted marine compounds in cancer therapy.
J Cancer Res Clin Oncol
January 2021
Purpose: This paper reviews marine compounds that target the mitogen-activated protein kinase (MAPK) signaling pathway and their main sources, chemical structures, major targeted cancers and possible mechanisms to provide comprehensive and basic information for the development of marine compound-based antitumor drugs in clinical cancer therapy research.
Methods: This paper searched the PubMed database using the keywords "cancer", "marine*" and "MAPK signaling pathway"; this search was supplemented by the literature-tracing method. The marine compounds screened for review in this paper are pure compounds with a chemical structure and have antitumor effects on more than one tumor cell line by targeting the MAPK signaling pathway.
Objective: To evaluate the diagnostic value of secreted frizzled-related protein 2 (SFRP2) gene promoter hypermethylation in stool for colorectal cancer (CRC).
Materials And Methods: Open published diagnostic study of SFRP2 gene promoter hypermethylation in stool for CRC detection was electronic searched in the databases of PubMed, EMBASE, Cochrane Library, Web of Science, and China National Knowledge Infrastructure. The data of true positive, false positive false negative, and true negative identified by stool SFRP2 gene hypermethylation was extracted and pooled for diagnostic sensitivity, specificity, and summary receiver operating characteristic (SROC) curve.