Publications by authors named "Zhiqun Yao"
Article Synopsis
- Teicoplanin is an antibiotic that can potentially harm cochlear hair cells and has shown to cause cell death in tested cultures, prompting investigation into its effects.
- The TIGAR protein plays a key role in promoting cell survival and its expression significantly decreases when cells are treated with teicoplanin, affecting cell viability and apoptosis levels.
- Enhancing TIGAR expression can protect cells from teicoplanin-induced damage, and using antioxidants like N-acetyl-L-cysteine shows promise in reducing harmful effects, suggesting TIGAR could be a target for preventing ototoxicity.
