Publications by authors named "Zhiqiang Gui"
Purpose: Previous research has documented cognitive deficits in survivors of papillary thyroid carcinoma (PTC).Our longitudinal study with large sample size, aims to assess the impact of menopausal status on cognitive function, elucidate related factors of cognitive impairment, and chart the trajectory of cognitive changes over time in female PTC patients.
Methods: In this longitudinal study, we administered the Montreal Cognitive Assessment (MoCA) to 322 female PTC patients over 40 years old, before surgery and at 3 and 6 months after surgery.
Article Synopsis
- * A study of 156 Asian patients found frequent genetic mutations in oncocytic tumors, specifically TERT promoter mutations in carcinomas, and identified 66 mitochondrial proteins that are significantly elevated in these tumors.
- * IDH2 was notably overexpressed in oncocytic tumors and could serve as a useful biomarker for differentiating between oncocytic adenomas and carcinomas, enhancing the understanding of their molecular pathology.
Article Synopsis
- The study investigates anxiety and depression levels in patients with papillary thyroid cancer (PTC) before and after surgery, highlighting a significant rise in these emotional states post-operation.
- Out of 320 participants, 13.8% experienced anxiety and 26.9% faced depression after their surgery, with findings indicating that gender and menopausal status significantly impact emotional well-being.
- The results suggest a need for enhanced psychological support for female and postmenopausal PTC patients following surgery, while recommending larger and longer studies for better insights.
Objective: Papillary thyroid microcarcinoma (PTMC) comprises more than 50% of all newly detected cases of papillary thyroid carcinoma (PTC). High-volume lymph node metastasis (involving >5 lymph nodes) (hv-LNM) is associated with PTMC recurrence. In half of the clinically node-negative (cN0) PTMC patients, central lymph node metastasis (CLNM) is pathologically present.
View Article and Find Full Text PDFObjective: The definition of the tumour diameter of micro-medullary thyroid carcinoma (micro-MTC) is insufficient. It is controversial to perform a completion thyroidectomy immediately for incidental T1 stage MTC.
Design: We used the Surveillance, Epidemiology and End Results (SEER) registry to retrospectively analyze all patients with T1 stage MTC diagnosed between 2004 and 2015.
Objective: Children with papillary thyroid cancer (PTC) have a higher invasive rate and distant metastasis rate, but the mortality rate is lower with unknown reasons. The majority of PTC cases comprise classical papillary thyroid carcinoma (CPTC) and follicular variant papillary thyroid carcinoma (FVPTC). This study aimed to determine the relationship between histopathological subtype and rate of distant metastasis and investigate factors influencing distant metastasis in pediatric PTC.
View Article and Find Full Text PDFObjective: The aim of this study was to explore the effect of total thyroidectomy (TT) and lobectomy (LT) on the prognosis of unilateral papillary thyroid carcinoma (PTC) with lateral cervical lymph node metastasis.
Methods: Patients with PTC and lateral cervical lymph node metastasis who underwent lateral cervical lymph node dissection between January 2007 and December 2016 were retrospectively reviewed. To investigate the effect of surgical procedure on the prognosis of lymph node metastasis patients, other high-risk factors such as extrathyroidal invasion and large tumor size were excluded.
BACKGROUND Papillary thyroid microcarcinoma (PTMC) measures less than 10 mm in diameter, is more common in the thyroid lobes, but rarely presents in the thyroid isthmus. This retrospective study aimed to compare patient outcomes following various types of surgery in patients with PTMC of the thyroid isthmus, at a single center in China. MATERIAL AND METHODS We analyzed the clinical data of patients with isthmus thyroid cancer treated at the First Hospital of China Medical University.
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