Publications by authors named "Zhinan Guo"

Introduction: Currently, nearly one-third of newly diagnosed Colorectal cancer (CRC) cases and associated deaths worldwide are from China. Among Chinese provinces, Fujian exhibited the highest CRC mortality rate. This study aims to analyze long-term trends of CRC epidemiology in Xiamen, Fujian, China.

View Article and Find Full Text PDF

Background: Gastric cancer remains one of the most common cancers and the leading cause of death in China. This study aims to describe the incidence, mortality, survival rates, and their changing trends of gastric cancer in Xiamen, China from 2011 to 2020.

Methods: Population-based cancer registry data were used to calculate the incidence, mortality, and survival rates of gastric cancer.

View Article and Find Full Text PDF

Ag, as a good bactericidal reagent, has been extensively used to prevent the growth and spread of bacteria and viruses. However, overcommit of Ag would leave residues in environments, which is toxic to the human body even under minimal exposure. In this case, a fast and high selective sensing method based on field effect transistors (FET) has been proposed for monitoring Ag in aqueous solutions.

View Article and Find Full Text PDF

To explore whether rs2073244 at PAX9 increased susceptibility for full-term low birth weight infants and whether indoors passive smoking exposure has a combined effect with rs2073244 on newborn low birth weight (LBW), a 1:2 paired case-control study of LBW newborns was conducted at Xiamen University Affiliated Women and Children's Hospital from March 2010 to October 2013. The rate of indoor passive smoking exposure in the LBW group was higher than it in the NBW group ( = 0.019).

View Article and Find Full Text PDF

Objectives: Quantitatively assess the severity and predict the mortality of interstitial lung disease (ILD) associated with Rheumatoid arthritis (RA) was a challenge for clinicians. This study aimed to construct a radiomics nomogram based on chest computed tomography (CT) imaging by using the ILD-GAP (gender, age, and pulmonary physiology) index system for clinical management.

Methods: Chest CT images of patients with RA-ILD were retrospectively analyzed and staged using the ILD-GAP index system.

View Article and Find Full Text PDF

Background: Reinfection of coronavirus disease 2019 (COVID-19) has raised concerns about how reliable immunity from infection and vaccination is. With mass testing for the virus halted, understanding the current prevalence of COVID-19 is crucial. This study investigated 1,191 public health workers at the Xiamen Center for Disease Control, focusing on changes in antibody titers and their relationship with individual characteristics.

View Article and Find Full Text PDF

Background & Aims: Whether maintaining optimal remnant cholesterol (RC) levels later in life may improve metabolic dysfunction-associated steatotic liver disease (MASLD) outcomes remained ambiguous. This study aimed to investigate the relationship between RC and MASLD in the elderly Chinese population.

Methods: A total of 131,868 subjects aged ≥ 65 years were included in this study.

View Article and Find Full Text PDF

Extracellular matrix (ECM) stiffness regulates development and homeostasis in vivo and affects both physiological and pathological processes. A variety of studies have demonstrated that mRNAs, such as Piezo1, integrin β1, and Yes-associated protein (YAP)/tafazzin (TAZ), can sense the mechanical signals induced by ECM stiffness and transmit them from the extracellular space into the cytoplasm. Non-coding RNAs (ncRNAs), such as microRNAs (miRNAs) and long non-coding RNAs (lncRNAs), have been reported to play important roles in various cellular processes.

View Article and Find Full Text PDF

Sodium-ion batteries (SIBs) as a replaceable energy storage technology have attracted extensive attention in recent years. The design and preparation of advanced anode materials with high capacity and excellent cycling performance for SIBs still face enormous challenges. Herein, a solution method is developed for in situ synthesis of anti-aggregation tellurium nanorods/reduced graphene oxide (Te NR/rGO) composite.

View Article and Find Full Text PDF

Background: The pivotal phase 3 efficacy clinical trial has demonstrated that a two-dose regimen of dNS1-RBD (Beijing Wantai Biological Pharmacy Enterprise, Beijing, China) is well-tolerated and provides wide protection against SARS-CoV-2 infection. However, the effectiveness of a single-dose regimen is still unknown. We aimed to estimate the effectiveness of one-dose of dNS1-RBD against symptomatic Omicron infections in real-world conditions.

View Article and Find Full Text PDF

Objective: Vaccine effectiveness can measure herd immunity, but the effectiveness of inactivated vaccines in Xiamen remains unclear. Our study was designed to understand the herd immunity of the COVID-19 inactivated vaccine against the SARA-CoV-2 Delta variant in the real world of Xiamen.

Methods: We carried out a test-negative case-control study to explore the vaccine's effectiveness.

View Article and Find Full Text PDF

Background: Quantitative assessment of the risk of local transmission from imported dengue cases makes a great challenge to the development of public health in China. The purpose of this study is to observe the risk of mosquito-borne transmission in Xiamen City through ecological and insecticide resistance monitoring. Quantitative evaluation of mosquito insecticide resistance, community population and the number of imported cases affecting the transmission of dengue fever (DF) in Xiamen was carried out based on transmission dynamics model, so as to reveal the correlation between key risk factors and DF transmission.

View Article and Find Full Text PDF

Background: Near 70% of hepatocellular carcinoma (HCC) recurrence is early recurrence within 2-year post surgery. Long non-coding RNAs (lncRNAs) are intensively involved in HCC progression and serve as biomarkers for HCC prognosis. The aim of this study is to construct a lncRNA-based signature for predicting HCC early recurrence.

View Article and Find Full Text PDF

Objective: This study uses four COVID-19 outbreaks as examples to calculate and compare merits and demerits, as well as applicational scenarios, of three methods for calculating reproduction numbers.

Method: The epidemiological characteristics of the COVID-19 outbreaks are described. Through the definition method, the next-generation matrix-based method, and the epidemic curve and serial interval ()-based method, corresponding reproduction numbers were obtained and compared.

View Article and Find Full Text PDF

Recently, two-dimensional (2D) layered nanomaterials have become promising candidates for surface-enhanced Raman scattering (SERS) substrates due to their unique characteristics of ultrathin layer structure, outstanding optical properties and good biocompatibility, significantly contributing to remarkable SERS sensitivity, stability, and compatibility. Unlike traditional SERS substrates, 2D nanomaterials possess unparalleled layer-dependent, phase transition induced and anisotropic optical properties, which as driving forces significantly promote the SERS performance and development, as well as greatly enrich the SERS substrates and provide versatile resources for SERS research. For a profound understanding of the SERS effect of 2D nanomaterials, a review concentrating on these driving forces for SERS enhancement on 2D nanomaterials is written here for the first time, which strongly emphasizes the importance and influence of these driving forces on the SERS effect of 2D nanomaterials, including their intrinsic physical and chemical properties and external influencing factors.

View Article and Find Full Text PDF

Objective: This study elaborated the natural history parameters of Delta variant, explored the differences in detection cycle thresholds (Ct) among cases.

Methods: Natural history parameters were calculated based on the different onset time and exposure time of the cases. Intergenerational relationships between generations of cases were calculated.

View Article and Find Full Text PDF

Background: In September 2021, there was an outbreak of coronavirus disease 2019 (COVID-19) in Xiamen, China. Various non-pharmacological interventions (NPIs) and pharmacological interventions (PIs) have been implemented to prevent and control the spread of the disease. This study aimed to evaluate the effectiveness of various interventions and to identify priorities for the implementation of prevention and control measures.

View Article and Find Full Text PDF
Article Synopsis
  • Two-dimensional indium selenide (InSe) is studied for its superior optoelectronic properties, particularly in transistors and photodetectors.
  • The -phase of InSe shows unique anisotropic behavior due to its crystal structure, making it promising for polarized photodetection applications.
  • Experiments confirmed strong anisotropic traits in -InSe, with significant differences in dark current and photocurrent across orientations, highlighting its potential for use in advanced photodetectors.
View Article and Find Full Text PDF

Two-dimensional black phosphorus (BP) has triggered tremendous research interest owing to its unique crystal structure, high carrier mobility, and tunable direct bandgap. Preparation of few-layer BP with high quality and stability is very important for its related research and applications in biomedicine, electronics, and optoelectronics. In this review, the synthesis methods of BP, including the preparation of bulk BP crystal which is an important raw material for preparing few-layer BP, the popular top-down methods, and some direct growth strategies of few-layer BP are comprehensively overviewed.

View Article and Find Full Text PDF

Thanks to the excellent optoelectronic properties, lead halide perovskites (LHPs) have been widely employed in high-performance optoelectronic devices such as solar cells and light-emitting diodes. However, overcoming their poor stability against water has been one of the biggest challenges for most applications. Herein, we report a novel hot-injection method in a Pb-poor environment combined with a well-designed purification process to synthesize water-dispersible CsPbBr nanocrystals (NCs).

View Article and Find Full Text PDF

2D layered materials turn out to be the most attractive hotspot in materials for their unique physical and chemical properties. A special class of 2D layered material refers to materials exhibiting phase transition based on environment variables. Among these materials, transition metal dichalcogenides (TMDs) act as a promising alternative for their unique combination of atomic-scale thickness, direct bandgap, significant spin-orbit coupling and prominent electronic and mechanical properties, enabling them to be applied for fundamental studies as catalyst materials.

View Article and Find Full Text PDF

Great success in 2D van der Waals (vdW) heterostructures based photodetectors is obtained owing to the unique electronic and optoelectronic properties of 2D materials. Performance of photodetectors based 2D vdW heterojunctions at atomic scale is more sensitive to the nanointerface of the heterojunction than conventional bulk heterojunction. Here, a nanoengineered heterostructure for the first-time demonstration of a nanointerface using an inserted graphene layer between black phosphorus (BP) and InSe which inhibits interlayer recombination and greatly improves photodetection performances is presented.

View Article and Find Full Text PDF

A PHP Error was encountered

Severity: Warning

Message: fopen(/var/lib/php/sessions/ci_sessionbapd04f6erb1ll4vsbtc521utjvtbni3): Failed to open stream: No space left on device

Filename: drivers/Session_files_driver.php

Line Number: 177

Backtrace:

File: /var/www/html/index.php
Line: 316
Function: require_once

A PHP Error was encountered

Severity: Warning

Message: session_start(): Failed to read session data: user (path: /var/lib/php/sessions)

Filename: Session/Session.php

Line Number: 137

Backtrace:

File: /var/www/html/index.php
Line: 316
Function: require_once