Effective Signal Extraction Algorithm for Cerebral Blood Oxygen Based on Dual Detectors.

Functional near-infrared spectroscopy (fNIRS) can dynamically respond to the relevant state of brain activity based on the hemodynamic information of brain tissue. The cerebral cortex and gray matter are the main regions reflecting brain activity. As they are far from the scalp surface, the accuracy of brain activity detection will be significantly affected by a series of physiological activities.

G-quadruplexes on chromosomal DNA negatively regulates topoisomerase 1 activity.

Human DNA topoisomerase 1 (Top1) is a crucial enzyme responsible for alleviating torsional stress on DNA during transcription and replication, thereby maintaining genome stability. Previous researches had found that non-working Top1 interacted extensively with chromosomal DNA in human cells. However, the reason for its retention on chromosomal DNA remained unclear.

Endoplasmic Reticulum-Targeting Quinazolinone-Based Lipophilic Probe for Specific Photoinduced Ferroptosis and Its Induced Lipid Dynamic Regulation.

Lethal lipid peroxidation caused by reactive oxygen species occurs in different types of programmed cell death, especially in ferroptosis. Ferroptosis inducers, which serve as small-molecule probes, can provide insight into the mechanism of ferroptosis and facilitate drug discovery. The classical ferroptosis inducers indirectly lead to lipid peroxidation; thus, it is difficult to explore lipid regulation during the ferroptotic process.

Research on Emotion Recognition Method of Cerebral Blood Oxygen Signal Based on CNN-Transformer Network.

In recent years, research on emotion recognition has become more and more popular, but there are few studies on emotion recognition based on cerebral blood oxygen signals. Since the electroencephalogram (EEG) is easily disturbed by eye movement and the portability is not high, this study uses a more comfortable and convenient functional near-infrared spectroscopy (fNIRS) system to record brain signals from participants while watching three different types of video clips. During the experiment, the changes in cerebral blood oxygen concentration in the 8 channels of the prefrontal cortex of the brain were collected and analyzed.

Thionation toward High-Contrast ACQ-DIE Probes by Reprogramming the Aqueous Segregation Behavior: Enlightenment from a Sulfur-Substituted G-Quadruplex Ligand.

Small-molecule-based fluorescent chemosensors provide powerful tools for analytical chemistry. However, their organic essence often "cursed" them for aggregation-caused quenching (ACQ) in an aqueous context. Albeit the praxis of the disaggregation-induced emission (DIE) strategy as a potential solution, it still awaited improvement due to the uncontrollability of the aggregation/segregation process.

Extramedullary plasmacytoma of the nasal inferior turbinate: a case report.

An extramedullary plasmacytoma (EMP) is a rare neoplasm characterized by monoclonal proliferation of plasma cells without features of multiple myeloma. Most EMPs occur in the head and neck region, especially in the aerodigestive tract. We herein report a case of an EMP arising from the nasal inferior turbinate.

Chemical composition and deterioration mechanism of Pleurotus tuoliensis during postharvest storage.

Pleurotus tuoliensis is a popular edible and medical mushroom, but it is highly perishable during postharvest storage. The quality parameters, chemical composition, malondialdehyde (MDA) concentration, and activity of metabolic enzymes were studied during 12 days of storage at 4 °C and 6 days of storage at 25 °C. Degradation was well described by changes in quality parameters, losses in nutritional value, increased metabolic enzyme activity, the accumulation of MDA concentrations, and the increase of total phenolic (TP) content.