To explore the relationship between serum levels of midkine and omentin-1 and the severity of sepsis in patients, and their prognostic value. A retrospective analysis was conducted on the clinical data of 180 sepsis patients. According to the severity of the patient's condition, they were separated into sepsis group ( = 76), severe sepsis group ( = 59), and sepsis shock group ( = 45).
View Article and Find Full Text PDFObjective: To investigate the correlation between the expression of cereblon (CRBN) protein in peripheral blood and the severity and prognosis of sepsis.
Methods: A total of 130 patients with sepsis admitted to our hospital were selected as the observation subjects (sepsis group). The patients were divided into mild group, moderate group and severe group according to their conditions.
Introduction: Severe pneumonia progresses rapidly, so early assessment of the severity and prognosis is crucial for reducing mortality rates.
Objective: We explore the role of serum microRNA-24 (miR-24) and microRNA-223 (miR-223) in the prognosis of severe pneumonia.
Methods: There were a total of 96 patients with general pneumonia, 94 patients with severe pneumonia, and 93 healthy people, who were enrolled in this study.
Central venous catheters (CVC) are widely used in critically ill patients given their benefits in monitoring vital signs, treatment administration, and renal replacement therapy in intensive care unit (ICU) patients, but these catheters have the potential to induce symptomatic catheter-related venous thrombosis (CRVT). This study reported the rate of symptomatic CRVT in ICU patients receiving CVC and analyzed the disease-related risk factors for symptomatic CRVT in ICU patients.A retrospective analysis was performed on the consecutive ICU 1643 critically ill patients with CVCs inserted from January 2015 to December 2019.
View Article and Find Full Text PDFAcute respiratory distress syndrome (ARDS) is very common in patients with severe acute pancreatitis (SAP), the early interventions are essential to the prognosis of SAP patients. We aimed to evaluate the risk factors for ARDS in SAP patients, to provide insights into the management of SAP.SAP patients treated in our hospital from June 1, 2018 to May 31, 2020 were included.
View Article and Find Full Text PDFProc Natl Acad Sci U S A
October 2017
Intense thunderstorms produce rapid cloud updrafts and may be associated with a range of destructive weather events. An important ingredient in measures of the potential for intense thunderstorms is the convective available potential energy (CAPE). Climate models project increases in summertime mean CAPE in the tropics and subtropics in response to global warming, but the physical mechanisms responsible for such increases and the implications for future thunderstorm activity remain uncertain.
View Article and Find Full Text PDFThe role of surface heat fluxes underneath cold pools is investigated using cloud-resolving simulations with either interactive or horizontally homogenous surface heat fluxes over an ocean and a simplified land surface. Over the ocean, there are limited changes in the distribution of the cold pool temperature, humidity, and gust front velocity, yet interactive heat fluxes induce more cold pools, which are smaller, and convection is then less organized. Correspondingly, the updraft mass flux and lateral entrainment are modified.
View Article and Find Full Text PDFThe effect of clouds on climate remains the largest uncertainty in climate change predictions, due to the inability of global climate models (GCMs) to resolve essential small-scale cloud and convection processes. We compare preindustrial and quadrupled CO2 simulations between a conventional GCM in which convection is parameterized and a "superparameterized" model in which convection is explicitly simulated with a cloud-permitting model in each grid cell. We find that the global responses of the two models to increased CO2 are broadly similar: both simulate ice-free Arctic summers, wintertime Arctic convection, and enhanced Madden-Julian oscillation (MJO) activity.
View Article and Find Full Text PDFElevated heating by the Tibetan Plateau was long thought to drive the South Asian summer monsoon, but recent work showed this monsoon was largely unaffected by removal of the plateau in a climate model, provided the narrow orography of adjacent mountain ranges was preserved. There is debate about whether those mountain ranges generate a strong monsoon by insulating the thermal maximum from cold and dry extratropical air or by providing a source of elevated heating. Here we show that the strength of the monsoon in a climate model is more sensitive to changes in surface heat fluxes from non-elevated parts of India than it is to changes in heat fluxes from adjacent elevated terrain.
View Article and Find Full Text PDFThe Tibetan plateau, like any landmass, emits energy into the atmosphere in the form of dry heat and water vapour, but its mean surface elevation is more than 5 km above sea level. This elevation is widely held to cause the plateau to serve as a heat source that drives the South Asian summer monsoon, potentially coupling uplift of the plateau to climate changes on geologic timescales. Observations of the present climate, however, do not clearly establish the Tibetan plateau as the dominant thermal forcing in the region: peak upper-tropospheric temperatures during boreal summer are located over continental India, south of the plateau.
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