Paenibacillus oenotherae W2-3 degraded Welan gum to produce growth-promoting oligosaccharides.

Based on the biodegradation of Welan gum, this paper studies the properties of Welan gum degrading enzymes, degradation rules, and the application of Welan gum oligosaccharides. In order to study the biodegradation of Welan gum, a strain W2-3 capable of degrading Welan gum, was isolated from soil and identified as Paenibacillus sp. The properties of Welan gum degrading enzymes, degradation rules, and the application of Welan gum oligosaccharides were studied.

Protective effects of puerarin combined with bone marrow mesenchymal stem cells on nerve injury in rats with ischemic stroke.

Background: Bone marrow mesenchymal stem cells (BM-MSCs) transplantation shows promise for treating ischemic stroke, but the ischemic environment that follows cerebral infarction hinders the survival of transplanted cells. We aimed to study the effects of puerarin (Pue) in combination with BM-MSCs on cerebral ischemic injury.

Methods: After middle cerebral artery occlusion (MCAO) models were prepared by suture-occluded method, rats were randomly allocated to the sham, MCAO, Pue (50 mg/kg), BM-MSCs (2×106), and BM-MSCs+Pue groups.

A novel CBM serving as a module for efficiently decomposing xanthan by modifying the processivity of hydrolase.

The inefficient decomposition of polysaccharides, particularly branched polysaccharides limits their large-scale industrial applications. Further understanding and modification of glycoside hydrolases (GHs) processivity is expected to overcome this limitation. Here, a novel xanthan-binding CBM (MiXBM), which was supposed to alter the processivity of GHs, was systematically characterized.

Experimental study of the biological properties of nmHA-SiO fiber materials prepared by electrospinning technology.

To study the biocompatibility of nanohydroxyapatite (nmHA)-SiO fiber material and its efficacy in guided bone regeneration. ① The cytotoxicity of the nmHA-SiO fiber material to MC3T3-E1 cells was determined by CCK-8 assay. The adhesion of cells on the surface of the material was observed.

Pretreatment of chitin depolymerization by expansin-like protein to improve hydrolysis efficiency.

Chitin is a polysaccharide similar to cellulose that contains abundant hydrogen bonds. Expansin-like proteins disrupt hydrogen bond networks, causing cellulose to swell and accelerating its degradation. We examined the effects of pretreatment with two expansin-like proteins, CxEXL22 ( sp.

Mendelian randomization study on insulin resistance and risk of hypertension and cardiovascular disease.

Observational studies have suggested that insulin resistance (IR) is associated with hypertension and various cardiovascular diseases. However, the presence of a causal relationship between IR and cardiovascular disease remains unclear. Here, we applied Mendelian randomization (MR) approaches to address the causal association between genetically determined IR and the risk of cardiovascular diseases.

Factors influencing immunogenicity and safety of SARS-CoV-2 vaccine in liver transplantation recipients: a systematic review and meta-analysis.

Background: This review summarizes the factors influencing the efficacy and safety of the COVID-19 vaccine in LTR through meta-analysis, hoping to provide strategies for vaccine use.

Methods: Electronic databases were screened for studies on mRNA vaccines in LTR. The primary outcome was the pooled seroconversion rate, and the secondary outcome was the incidence of adverse events+breakthrough infections.

Triamcinolone acetonide suppressed scar formation in mice and human hypertrophic scar fibroblasts in a dose-dependent manner.

A hypertrophic scar is a complex medical problem. The study of triamcinolone acetonide for the treatment of scars is necessary. The 7mm full-thickness skin wounds were created on the back of BALA/c mice to construct the animal scar model.

First report of the ectomycorrhizal fungal community associated with two herbaceous plants in Inner Mongolia, China.

Ectomycorrhizal (EM) fungi play a vital role in ensuring plant health, plant diversity, and ecosystem function. However, the study on fungal diversity and community assembly of EM fungi associated with herbaceous plants remains poorly understood. Thus, in our study, and in the subalpine meadow of central Inner Mongolia, China were selected for exploring EM fungal diversity and community assembly mechanisms by using llumina MiSeq sequencing of the fungal internal transcribed spacer 2 region (ITS2).

Management of the Uncinate Process in No-Touch Laparoscopic Pancreaticoduodenectomy.

Laparoscopic pancreatoduodenectomy (LPD) is a demanding abdominal operation that necessitates meticulous surgical skills and teamwork. The management of the pancreatic uncinate process is one of the most important and difficult processes in LPD because of its deep anatomical location and difficult exposure. Complete resection of the uncinate process and mesopancreas has become the cornerstone of LPD.

Atomic layer deposition of Er-doped yttrium aluminum gallium garnet nanofilms with tunable crystallization and electroluminescence properties.

Polycrystalline erbium-doped Y(AlGa)O (Er-YAGG) nanofilms with various Al/Ga compositions are deposited on silicon using atomic layer deposition followed by annealing at different temperatures. The Al/Ga ratios and the corresponding annealing temperatures required for crystallization are confirmed by investigating the diffraction patterns and micro-morphologies. The co-alloying of Al and Ga compositions controllably changes the lattice constant and impacts the grain growth.

Bright white electroluminescence from polycrystalline dysprosium-doped yttrium gallium garnet nanofilms fabricated by atomic layer deposition on silicon.

Bright white emission is obtained under electrical excitation from dysprosium doped YGaO garnet (YGG:Dy) nanofilms fabricated by atomic layer deposition on silicon substrates. Electroluminescence (EL) composed of yellow (580 nm) and blue (482 and 492 nm) emission corresponds to the CIE chromaticity coordinates of (0.3568, 0.

Along with cyclic electron flow and non-photochemical quenching, water-to-water cycle is involved uniquely in alleviating Zn stress-caused photodamage in Melia azedarach.

Zinc (Zn) is a widespread industrial pollutant that has detrimental effects on plant growth and development. Photoprotective properties ensure plant survival during stress by protecting the photosynthetic apparatus. This occurs via numerous mechanisms, including non-photochemical quenching (NPQ), cyclic electron flow (CEF) and the water-to-water cycle (WWC).

Narrow UVB-Emitted YBO Phosphor Activated by Bi and Gd Co-Doping.

Y(GdBi)BO phosphors (x = 0, 0.2, 0.4, 0.

An Insight into the Essential Role of Carbohydrate-Binding Modules in Enzymolysis of Xanthan.

To date, due to the low accessibility of enzymes to xanthan substrates, the enzymolysis of xanthan remains deficient, which hinders the industrial production of functional oligoxanthan. To enhance the enzymatic affinity against xanthan, the essential role of two carbohydrate binding modules-CBMx and CBM84, respectively, derived from sp. XT11 and sp.

Degradation of atrazine in river sediment by dielectric barrier discharge plasma (DBDP) combined with a persulfate (PS) oxidation system: response surface methodology, degradation mechanisms, and pathways.

Single degradation systems based on dielectric barrier discharge plasma (DBDP) or persulfate (PS) oxidation cannot achieve the desired goals (high degradation efficiency, high mineralization rate, and low product toxicity) of degrading atrazine (ATZ) in river sediment. In this study, DBDP was combined with a PS oxidation system (DBDP/PS synergistic system) to degrade ATZ in river sediment. A Box-Behnken design (BBD) including five factors (discharge voltage, air flow, initial concentration, oxidizer dose, and activator dose) and three levels (- 1, 0, and 1) was established to test a mathematical model by response surface methodology (RSM).

Causal effect of iron status on lung function: A Mendelian randomization study.

Background: The association between systemic iron status and lung function was conflicting in observational studies. We aim to explore the potential causal relationships between iron status and the levels of lung function using the two-sample Mendelian randomization (MR) design.

Methods: Genetic instruments associated with iron status biomarkers were retrieved from the Genetics of Iron Status (GIS) consortium ( = 48,972).

Inhibition of Chitosan with Different Molecular Weights on Barley-Borne during Barley Malting Process for Improving Malt Quality.

There are many contaminations in barley that are often associated with malt and beer quality issues. Thus, it is important to find a biological antifungal agent to prevent the growth of during malting. Minimum inhibition concentration (MIC) of chitosan for mycelial growth and spore germination of was 2.

Fatty acid-binding protein 5 aggravates pulmonary artery fibrosis in pulmonary hypertension secondary to left heart disease via activating wnt/β-catenin pathway.

Introduction: Pulmonary hypertension secondary to left heart disease (PH-LHD) is a common and fatal disease. However, no effective therapeutic targets have been identified.

Objectives: Here, we set out to illustrate the functional role and underlying mechanisms of fatty acid-binding protein 5 (FABP5) in PH-LHD development.

Exploration of dilated cardiomyopathy for biomarkers and immune microenvironment: evidence from RNA-seq.

Background: The pathogenic mechanism of dilated cardiomyopathy (DCM) remains to be defined. This study aimed to identify hub genes and immune cells that could serve as potential therapeutic targets for DCM.

Methods: We downloaded four datasets from the Gene Expression Omnibus (GEO) database: GSE141910, GSE3585, GSE42955 and GSE79962.

Polycrystalline Er-doped YGaO nanofilms fabricated by atomic layer deposition on silicon at a low temperature and the exploration on electroluminescence performance.

Polycrystalline erbium-doped YGaO garnet (YGG) nanofilms are deposited by atomic layer deposition on Si substrates after annealing down to 800 °C, based on which ∼1.53 μm electroluminescence (EL) devices are fabricated. The optimal EL performance depends on the adjustment of Y/Ga ratio and GaO interlayer thickness within the nanolaminates, which exert no prominent impact on the crystallization and film morphology of YGG nanofilms.

Development of bacterial resistance induced by low concentration of two-dimensional black phosphorus mutagenesis.

The wide use of nano-antibacterial materials has triggered concerns over the development of nanomaterials-associated bacterial resistance. Two-dimensional (2D) black phosphorus (BP) as a new class of emerging 2D nanomaterial has displayed excellent antibacterial performance. However, whether bacteria repeatedly exposed to 2D BP can develop resistance is not clear.

Bergenin alleviates Diabetic Retinopathy in STZ-induced rats.

Diabetic retinopathy (DR) is the key cause of blindness and visual impairment in diabetes patients around the world. The high levels of oxidative stress in diabetes patients cause diabetic retinopathy. In addition to being an antioxidant, Bergenin also works as an immunosuppressant, an anti-inflammatory, and anticarcinogenic against hepatocarcinoma.