Publications by authors named "Zhimin Liu"

Porcine deltacoronavirus (PDCoV) and transmissible gastroenteritis coronavirus (TGEV), the two causative agents of porcine diarrhea, have been reported to be at risk of cross-species transmission, including to humans. However, the potential host range in which these two CoVs interact remains unclear. We screened 16 animal counterparts for porcine aminopeptidase N (APN), the receptor of PDCoV and TGEV, and found that APNs from eight of 17 animals could bind to the receptor-binding domains (RBDs) of PDCoV and TGEV.

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  • CRAFT is a fusion technology facility in China focused on developing and validating fusion technology through methods like neutral beam injection.
  • A new negative ion based neutral beam injector is being created with a beam energy of 400 keV, utilizing a core snubber for surge suppression in its power supply system.
  • The design of the core snubber involves careful consideration of transmission line characteristics, and initial testing shows it effectively suppresses peak ignition current and oscillation.
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Objective: To evaluate prognostic factors in women with invasive VSCC at Sun Yat-sen University Cancer Center (SYSUCC).

Methods: 137 patients with VSCC at SYSUCC were retrospectively analyzed. The Kaplan-Meier method assessed the overall survival (OS) and progression-free survival (PFS) time.

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Aim: This study aimed to investigate the prevalence and associated factors of hypokalemia in patients with acute ischemic stroke.

Methods: A cohort of 996 patients was assessed using a general data questionnaire, laboratory indicators, the NIH Stroke Scale (NIHSS), the Barthel Index (BI), the Frail scale, Nutritional Risk Screening (NRS-2002), and the Kubota drinking water test.

Results: Among the 996 patients, 205 (20.

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Liver ischemia-reperfusion (I/R) injury is a critical issue in clinical settings, particularly in liver transplantation and resection, leading to severe hepatocellular dysfunction and organ failure. This study investigates the role of fibrinogen and platelets in liver I/R injury, focusing on their distribution and pathophysiological impact within liver lobules. Using a mouse model, we examined the expression and localization of fibrinogen and platelets at various time points postreperfusion.

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Positioning and autonomous landing are key technologies for implementing autonomous flight missions across various fields in unmanned aerial vehicle (UAV) systems. This research proposes a visual positioning method based on mirrored field-of-view expansion, providing a visual-based autonomous landing strategy for quadrotor micro-UAVs (MAVs). The forward-facing camera of the MAV obtains a top view through a view transformation lens while retaining the original forward view.

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Selective hydrogenolysis of biomass-derived furanic compounds is a promising approach for synthesizing aliphatic polyols by opening the furan ring. However, there remains a significant need for highly efficient catalysts that selectively target the Csp-O bond in the furan ring, as well as for a deeper understanding of the fundamental atomistic mechanisms behind these reactions. In this study, we present the use of Pt-Fe bimetallic catalysts supported on layered double hydroxides [PtFe /LDH] for the hydrogenolysis of furanic compounds into aliphatic alcohols, achieving over 90% selectivity toward diols and triols.

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Universities, as agents of change, are expected to contribute to society's most pressing challenges, particularly the 21st century's central issue of sustainability. Amid growing expectations from governments, society, and an increasingly conscientious student body, universities have undergone significant institutional adjustments to incorporate sustainability into their core missions of education, research, and outreach. As universities worldwide increasingly engage in sustainability practices, the question arises: How do these sustainability endeavours correlate with academic performance on a global scale? This article, using data from the QS Sustainability Ranking and four prominent academic ranking (THEWUR, ARWU, QSWUR and USWUR), investigates this link.

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The pursuit of sustainable practices through the chemical recycling of polyamide wastes holds significant potential, particularly in enabling the recovery of a range of nitrogen-containing compounds. Herein, we report a novel strategy to upcycle polyamide wastes to tertiary amines with the assistance of H in acetic acid under mild conditions (e.g.

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This study examines how multicomponent exercise nursing interventions affect the state of frailty, daily activities, and quality of life in elderly stroke patients with frailty. A total of 125 elderly stroke patients with frailty were randomly assigned to either a control group ( = 62) or an intervention group ( = 63). The control group received standard nursing care, while the intervention group received a multicomponent exercise nursing intervention in addition to standard care.

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Due to the high stability and less maintenance, the radio frequency (RF) driven ion source is preferred for the neutral beam injection (NBI) system. In a popular design of the RF ion source for NBI application, a Faraday shield (FS) is installed inside the RF plasma driver to protect the discharge tube. However, the FS also brings some drawbacks, such as lowering the RF power transfer and increasing the processing difficulty.

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Cordyceps chanhua, an important cordycipitoid medical mushroom with wide use in Asia, has gained attention for its bioactive component beauvericin (BEA), which is of medicinal value as a drug lead, but also of food safety risk. Recent observations by our group revealed a significant decrease of BEA content in C. chanhua when exposed to light, but the underlying regulatory mechanisms remain elusive.

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  • The standard treatment for anal squamous cell carcinoma (ASCC) is concurrent chemoradiotherapy (CRT), but about 33% of patients still face treatment failure.
  • A study involving 100 nonmetastatic ASCC patients compared outcomes of surgery, CRT alone, and CRT with immunotherapy (CRT-I) over a median follow-up of 30.7 months, finding that CRT-I provided the best survival rates.
  • Although 26% of patients experienced severe side effects, those receiving CRT-I had the highest overall survival, with ongoing research into combining CRT with immunotherapy further improving treatment options for ASCC.
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Coupling with the nitrate electroreduction reaction (NitRR), the electrosynthesis of cyclohexanone oxime (CHO, the vital feedstock in the nylon-6 industry) from cyclohexanone provides a promising alternative to the traditional energy consumption process. However, it still suffers from low efficiency because selective production of *NHOH intermediate from NitRR under large current densities is challenging. We here report a CuMoO/nitrogen-doped carbon (NC) electrocatalyst with high-density Cu-Mo dual sites for NitRR to selectively produce and stabilize *NHOH, with the subsequent cyclohexanone oximation achieving the highest CHO Faradaic efficiency of 94.

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Background: Left bundle branch area pacing (LBBAP) is safe and effective, but studies in older patients are lacking. This study compared the clinical and echocardiographic outcomes of LBBAP and right ventricular pacing (RVP) in patients aged ≥75 years.

Methods: This prospective observational study included older patients with symptomatic bradycardia who underwent LBBAP or RVP between 2019 and 2022.

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The accumulation of polyethylene microplastic (PE-MPs) in soil can significantly impact plant quality and yield, as well as affect human health and food chain cycles. Therefore, developing rapid and effective detection methods is crucial. In this study, traditional machine learning (ML) and H2O automated machine learning (H2O AutoML) were utilized to offer a powerful framework for detecting PE-MPs (0.

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Background: We aim to develop a new prognostic model that incorporates inflammation, nutritional parameters and clinical-pathological features to predict overall survival (OS) and disease free survival (DFS) of breast cancer (BC) patients.

Methods: The study included clinicopathological and follow-up data from a total of 2857 BC patients between 2013 and 2021. Data were randomly divided into two cohorts: training (n=2001) and validation (n=856) cohorts.

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Understanding molecular state evolution is central to many disciplines, including molecular dynamics, precision measurement, and molecule-based quantum technology. Details of this evolution are obscured when observing a statistical ensemble of molecules. Here, we report real-time observations of thermal radiation-driven transitions between individual states ("jumps") of a single molecule.

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  • Glioma, especially glioblastoma (GBM), is an aggressive brain tumor with a poor prognosis, and its progression is influenced by the tumor microenvironment (TME) that supports invasion and drug resistance.
  • The study analyzed various genetic data to identify malignant cell subclusters within glioma, revealing specific gene expression patterns and highlighting the role of tumor-infiltrating immune cells, particularly monocytes, in the TME.
  • A prognostic model was developed based on 15 differentially expressed immune-related genes (DE-ARGs), which categorized glioma samples into two molecular clusters, indicating a potential link between angiogenesis and immune system activation.
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Upcycling biopolyesters (, polyglycolic acid, PGA) into chemicals is an interesting and challenging topic. Herein, we report a novel protocol to upgrade biopolyesters derived from hydroxyl carboxylic acids over ionic liquids with a hydroxyl carboxylate anion (, glycolate, lactate) into various chemicals under metal-free conditions. It is found that as hydrogen-bond donors and acceptors, hydroxyl carboxylate anions can readily activate the ester group hydrogen bonding and decompose biopolyesters autocatalyzed-transesterification to form hydroxyl carboxylate anion-based intermediates.

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In this study, an enhanced selective recognition strategy was employed to construct a novel solid-phase microextraction fiber coating for the detection of 17β-estradiol, characterized by the combination of aptamer biorecognition and molecularly imprinted polymer recognition. Benefiting from the combination of molecularly imprinted and aptamer, aptamer-molecularly imprinted (Apt-MIP) fiber coating had synergistic recognition effect. The effects of pH, ion concentration, extraction time, desorption time and desorption solvent on the adsorption capacity of Apt-MIP were investigated.

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The chemical recycling of polyester wastes is of great significance for sustainable development, which also provides an opportunity to access various oxygen-containing chemicals, but generally suffers from low efficiency or separation difficulty. Herein, we report anatase TiO supported Ru and Mo dual-atom catalysts, which achieve transformation of various polyesters into corresponding diols in 100% selectivity via hydrolysis and subsequent hydrogenation in water under mild conditions (e.g.

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Polycyclic aromatic hydrocarbons (PAHs) have long been globally distributed, and almost worldwide people are exposed to varying degrees of PAHs. Aqueous medium is an important transmission route of PAHs, but the detection of PAHs in aqueous environment has been a challenge. Herein, a magnetic hypercrosslinked polymer microsphere (FeO@SiO-PS@HCP) was developed for the effective detection of PAHs.

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Nonreciprocal devices are essential and crucial in optics for source protection and signal separation. A hybrid grating system consisting of a silicon grating, a graphene layer, and a silicon waveguide layer is employed to create a high-Q quasi-BIC (bound state in the continuum). Then, the high-Q properties of the quasi-BIC are harnessed to enhance the third-order nonlinear effect of silicon, thereby improving the nonreciprocal characteristics of the device.

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Introduction: Quality evaluation of Huang-qin is significant to ensure its clinical efficacy.

Objective: This study aims to establish an accurate, rapid and comprehensive Huang-qin quality evaluation method to overcome the time-consuming and laborious shortcomings of traditional herbal medicine quality assessment methods.

Methods: The contents of baicalin, baicalein and scutellarin in Huang-qin from five different origins were analyzed by FT-IR and NIR spectra combined with multivariate data technology.

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