Publications by authors named "Zhilong Mu"

Background: Kawasaki disease (KD) is a pyretic ailment predominantly observed in children aged below 5 years. There is currently a dearth of precise markers for timely identification of incomplete Kawasaki disease (IKD). It is imperative to develop updated, comprehensive, and evidence-based guidelines to effectively direct clinical practice.

View Article and Find Full Text PDF

Kawasaki disease (KD) is a febrile disease mainly observed in children aged <5 years, with medium- and small-vessel vasculitis as the main lesion. Although KD has been reported for more than 50 years and great progress has been made in the etiology and pathology of KD in recent years, there is still a lack of specific indicators for the early diagnosis of KD, especially with more difficulties in the diagnosis of incomplete Kawasaki disease (IKD). At present, there are no clear diagnostic criteria for IKD, which leads to the failure of the timely identification and standardized treatment of IKD in clinical practice and even induce the development of coronary artery lesion.

View Article and Find Full Text PDF

Kawasaki disease is an acute, self-limiting vasculitis in children. Early treatment is necessary to prevent cardiovascular complications. The acute phase of Kawasaki disease may present with hemodynamic instability.

View Article and Find Full Text PDF

The cases of coronavirusdisease 2019 in children have been increasing with the ongoing pandemic.The finding suggests children have mild symptoms and a short course of the disease. Angiotensinconverting enzyme-2 mediates entry of the virus into the cell, the combination of virus and ACE2 leads to an increase in activity of angiotensin II, resulting in acute injury to lungs, myocardium and other organs.

View Article and Find Full Text PDF
Article Synopsis
  • Kawasaki disease is the leading cause of acquired heart disease in children, leading to serious cardiovascular issues like coronary artery lesions and giant aneurysms, affecting their overall health.
  • In July 2020, the Japanese Circulatory Society and the Japanese Society of Cardiac Surgery released a guideline to guide the diagnosis and management of Kawasaki disease's cardiovascular effects.
  • The article discusses how to evaluate the severity of Kawasaki disease and outlines approaches for its diagnosis, treatment, and long-term management based on the established guidelines.
View Article and Find Full Text PDF