Publications by authors named "Zhikang Zheng"

Background: Gram-negative bacteria are the primary pathogens of endometritis in dairy cows. LPS, the primary pathogenic agent of gram-negative bacteria, triggers an ROS increase, ultimately causing epithelial-mesenchymal transformation (EMT). Its significance in endometritis pathogenesis in dairy cows cannot be overlooked.

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  • - This study evaluated the effectiveness of a 141-gene next-generation sequencing (NGS) panel in diagnosing and classifying myeloid neoplasms (MN) according to new guidelines (WHO-HAEM5 and ICC) compared to an older version (WHO-HAEM4R).
  • - Testing showed high mutation detection rates: 93% for acute myeloid leukemia, 89% for myelodysplastic syndrome, and 94% for myeloproliferative neoplasms, indicating the NGS panel's efficiency in identifying diseases.
  • - The findings revealed that NGS provided deeper subclassification insights than the WHO-HAEM5 framework and confirmed various mutations in myeloprolifer
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Objective: Recent studies have found that polycyclic aromatic hydrocarbons (PAHs) exposure may increase the risk of cardiovascular disease. The present study aimed to explore the association between PAHs exposure and severe abdominal aortic calcification (AAC) in adults.

Methods: Data were collected from the 2013-2014 National Health and Nutrition Examination Survey.

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Background: Albuminuria is a hallmark of diabetic kidney disease (DKD) that promotes its progression, leading to renal fibrosis. Renal macrophage function is complex and influenced by macrophage metabolic status. However, the metabolic state of diabetic renal macrophages and the impact of albuminuria on the macrophage metabolic state are poorly understood.

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