Research progress of the SLFN family in malignant tumors.

The Schlafen (SLFN) gene family has emerged as a critical subject of study in recent years, given its involvement in an array of cellular functions such as proliferation, differentiation, immune responses, viral infection inhibition, and DNA replication. Additionally, SLFN genes are linked to chemosensitivity, playing a pivotal role in treating malignant tumors. Human SLFNs comprise three domains: the N-terminal, middle (M), and C-terminal.

Advances in circulating tumor cells for early detection, prognosis and metastasis reduction in lung cancer.

Globally, lung cancer stands as the leading type of cancer in terms of incidence and is the major source of mortality attributed to cancer. We have outlined the molecular biomarkers for lung cancer that are available clinically. Circulating tumor cells (CTCs) spread from the original location, circulate in the bloodstream, extravasate, and metastasize, forming secondary tumors by invading and establishing a favorable environment.

[Potential Ecological Risk Assessment and Source Analysis of Heavy Metals in Soil-crop System in Xiong'an New District].

In order to evaluate the distribution characteristics of fluorine geochemistry in the surface soil and human health risk in Xiong'an New District, GIS spatial analysis and correlation analysis were used to analyze the depleted and enriched features and influencing factors of soil fluoride and to carry out the soil fluoride health risk assessment. The uncertainty of the health risk assessment results was studied based on the Monte Carlo stochastic simulation. The results showed that the average content of fluorine was 641 mg·kg, which was 1.

[Potential Ecological Risk Assessment and Source Analysis of Heavy Metals in Soil-crop System in Xiong'an New District].

In order to evaluate the potential ecological risk of heavy metals in the soil-crop system in the Xiong'an New District, the heavy metal contents and forms in wheat seed and root soil samples are analyzed, and the comprehensive pollution index (IPI), potential ecological risk index (RI), bio-enrichment coefficient (BFC), risk assessment code (RAC), principal component analysis, and correlation analysis are used to assess the potential ecological risk of heavy metals and analyze their sources. The results indicate that the average content of Cd, Cu, Pb, and Zn in the root soil is significantly higher than the soil background value in Hebei province. The IPI ranges from 0.

[Geochemical Survey Method of Land Quality in Land Parcel Scale City: A Case Study of the Initial Area of the Xiong'an New District].

In order to evaluate the land quality geochemical survey achievement in the service of the accurate management of urban land resources, the initial area of the Xiong'an New District as urbanization pathfinder in China is chosen as the research subject. The sample points were set by differential classification, and the spatial interpolation accuracy of the soil elements at a plot scale and a quantitative assessment of the consistency of the land plot (pattern spot) prediction evaluation were studied under the conditions of different sampling densities. The regional geochemical variation values randomly distributed on the plane can be reflected quantitatively by differential classification sampling, which can meet the basic demand of the quality attribute of a single plot (map spot) by the accurate management of urban land resources.

[Selenium Threshold for the Delimitation of Natural Selenium-Enriched Land].

The nationwide Se-enriched threshold plays a key role in identifying China's selenium-enriched land resources and developing characteristic agricultural practices. In this study, we used the cooperative data of 10222 sets of crops and roots in China for the past 10 years with a systematic analysis of the selenium content characteristics of the soil and the status of selenium-enriched agricultural products. The preliminary estimates of the selenium-enriched threshold based on a bulk crop-soil linear model and population selenium-intake are presented.

[Discussion on Key Issues of Geochemical Monitoring of Soil Heavy Metal in Xiong'an New District].

To build a soil environmental quality monitoring network and collect the systematic soil geochemical data of heavy metals before and after the construction of Xiong'an New District(XND), long-term variations in soil heavy metal levels during the XND construction were monitored based on the land quality geochemical survey monitoring data and the geochemical distribution of heavy metals. Parameters such as sampling density, sampling quantity, and sampling period were estimated to construct the geochemical monitoring network, which provides a reference for the future long-term monitoring of soil heavy metal geochemistry in XND. The results indicate that variations in the amount of heavy metals As, Cd, Cu, Hg, and Pb are greater than 36%, while the nugget coefficients of Cd, Cu, and Pb are greater than 75% because of the superposition of manmade sources on the high natural background levels.

[Diagnosis and treatment of bilateral bronchial foreign body in children].

Objective: To discuss the clinical characteristics of bilateral bronchial foreign body in children, increase the curative rate and reduce the complications.

Method: The clinical data of 35 cases with bilateral bronchial foreign body in children were retrospectively analysed, including surgery, key surgery points, and postoperative combined therapy.

Result: The foreign bodies of all cases were removed under intravenous general and tropical anesthesia without complications.

Clinicopathological features and prognosis assessment of extranodal follicular dendritic cell sarcoma.

Aim: To establish a model for prognosis assessment of extranodal follicular dendritic cell (FDC) sarcoma.

Methods: Nine lesions were examined by routine and molecular approaches. Clinicopathological factors from the new cases and 97 reported cases were analyzed for their prognostic values.

[Study on correlated factors and clinical features of fungal rhinosinusitis].

Objective: To investigate the correlated factors and clinical features of fungal rhinosinusitis.

Methods: The clinical data of 110 patients with fungal rhinosinusitis treated by surgery and another group of 110 patients with chronic rhinosinusitis who were sampled randomly between January 1999 and June 2004 in our hospital were retrospectively compared. The correlated factors and the clinical features of fungal rhinosinusitis were investigated by using the multiple factor Logistic regression analysis and chi-square test.