Publications by authors named "Zhijuan Gao"

Article Synopsis
  • There has been a notable rise in surface ozone (O) levels in the troposphere, which negatively impacts ecosystems, human health, and climate change, particularly affecting rice crops.
  • A study analyzed ozone data from 2015 to 2020 in Sichuan province, revealing average ozone concentrations during the rice growing season of 55.4 to 69.3 μg/m, with substantial yield losses of 4.9-9.2% due to ozone pollution.
  • Economic losses from these yield reductions are significant, estimated between 2079.08-4149.89 million Yuan, primarily affecting areas like the Chengdu Plain, highlighting the need for stricter ozone reduction strategies to protect agriculture and food security
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Article Synopsis
  • The study aimed to assess the effectiveness and safety of foot baths using Tangbi Waixi Decoction for patients with diabetic peripheral neuropathy (DPN) through a multicenter double-blinded randomized controlled trial.
  • A total of 632 patients participated, receiving either a high or low dose of herbal treatment for two weeks, with results showing improvements in nerve function and reduced pain scores in both groups after 12 weeks.
  • However, the lower dose was found to be more effective than the higher dose, and overall, there were no significant differences in adverse events between the treatment and control groups, indicating the treatment was safe.
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Nitric oxide (NO) and reactive oxygen species (ROS) function as signaling molecules in a number of critical signal transduction pathways in plants, including plant biotic interactions. In addition to the role of plant-derived NO and ROS in plant resistance, which has been well documented, pathogen-produced NO and ROS have recently emerged as important players in fungal development and pathogenesis. However, the effects of pathogenic fungi-derived NO and ROS on signaling pathways during fungal pre-infection development remain unknown.

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Objective: To explore the expression of interleukin-25 (IL-25) in chronic rhinosinusitis with nasal polyps (CRSwNP) and its potential significance in pathogenesis.

Method: IL-25 expression in blood was detected by enzyme-linked immunosorbent assay (ELISA). IL-25 expression in tissue was detected by immunohistochemistry (LSAB method) from polyps (68 CRSwNP patients) and 55 inferior turbinate mucosa from patients with deviation of nasal septum served as control.

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Benzo[a]pyrene (BaP), a ubiquitous environmental pollutant, is formed by incomplete combustion of organic materials, and causes oxidative damage to cells and tissues due to reactive oxygen species (ROS). The purpose of this study is to investigate the inhibition of Tanshinone IIA and Baicalin on the formation of BaP as well as the cytotoxicity in human umbilical vein endothelial cells (HUVECs) induced by BaP. The results showed that BaP formations in mainstream smoke were inhibited by 21μg/cigarette of Tanshinone IIA with a 12.

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Objective: To establish a HPLC method for the analysis of Danshensu (DSS), protocatechuic acid (PA) and protocatechuic aldehyde (PAL) of Xiangdan injection in rat's plasma, and to study pharmacokinetic characteristics of Xiangdan injection components in rats with m-hydroxybenzoic acid as internal standard.

Method: protein was precipitated by 10% trichloroacetic acid and extracted by ethyl acetate. The plasma concentration was detected by HPLC, The pharmacokinetics parameters of DSS, PA and PAL were calculated by DAS2.

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Objective: The aim of this study was to evaluate the accumulation of transforming growth factor (TGF)-beta1 and basic fibroblast growth factor (bFGF) at gene and protein levels in lens epithelial cells of anterior subcapsular congenital cataracts (ASCC).

Design: Case-control study and analysis.

Participants: Twenty-six eyes with ASCC were studied, and 14 eyes with transparent lenses were used as controls.

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