Publications by authors named "Zhijian Weng"
To determine a rapid and accurate method for locating the keypoint and "keyhole" in the suboccipital retrosigmoid keyhole approach. (1) Twelve adult skull specimens were selected to locate the anatomical landmarks on the external surface of the skull.The line between the infraorbital margin and superior margin of the external acoustic meatus was named the baseline.
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- Secondary spinal cord injury (SSCI) occurs after the initial spinal cord injury and involves complex biological processes like inflammation and scar formation, complicating recovery.
- Bioactive additives such as drugs and cells are crucial for treatment but face challenges in effective delivery and retention.
- Hydrogels have emerged as a promising solution for delivering these additives, promoting nerve cell growth, and can be modified to enhance their therapeutic effects for SSCI treatment.
Article Synopsis
- The study assessed the effectiveness of preoperative multimodal image fusion and intraoperative Dyna CT in aiding Percutaneous balloon compression (PBC) surgery for 24 patients with primary trigeminal neuralgia (PTN).
- All patients experienced immediate pain relief post-surgery, with complications primarily consisting of facial numbness and mild weakness, but no serious side effects were reported.
- The findings suggest that multimodal imaging improves surgical planning and outcomes, with a high success rate and minimal recurrence of pain after an average follow-up of 9.6 months.
Objective: We aimed to explore a method of precise localization within craniotomy based on skull anatomical landmarks via the suboccipital retrosigmoid approach.
Method: Craniometric measurements were taken from 15 adult dry skulls and eight cadaver head specimens. In the anatomical study, the keypoint corresponded to the transverse-sigmoid sinus junction's corresponding point on the external surface of the temporal mastoid process, eight cadaveric heads underwent a simulated craniotomy using the suboccipital retrosigmoid approach.
Article Synopsis
- The study aimed to find the exact location for a keypoint in craniotomy using the retrosigmoid keyhole approach, analyzing 20 dry skulls and 10 wet cadaveric specimens.
- A method was created to identify the keypoint based on anatomical landmarks, with no significant differences noted between the left and right sides of the skull.
- The procedure proved to be safe with no venous injuries, averaging a craniotomy time of about 29 minutes while maintaining a clear operating field.
Background: Spinal glioma is a nervous system tumor that tends to relapse and has no specific prognostic molecular biomarkers. Thus, a stable and reproduceable animal research model of spinal glioma is urgently needed.
New Method: We established a new in situ tumor xenograft model of spinal glioma using nude mice.
Background: Spinal schwannoma is a common benign tumor. However, the high recurrence rate and incidence of surgical complications are unsolved problems.
Objective: To propose a morphological classification of spinal schwannoma based on tumor-membrane relationships to increase the gross total resection (GTR) rate and to decrease the incidence of surgical complications.
Glioblastoma (GBM) is the most common and aggressive brain tumor, characterized by its propensity to invade the surrounding brain parenchyma. The effect of extracellular high-mobility group box 1 (HMGB1) protein on glioblastoma (GBM) progression is still controversial. p62 is overexpressed in glioma cells, and has been associated with the malignant features and poor prognosis of GBM patients.
View Article and Find Full Text PDFPurpose: Glioblastoma, a common malignant intracranial tumor, has the most dismal prognosis. Autophagy was reported to act as a survival-promoting mechanism in gliomas by inducing epithelial-to-mesenchymal transition (EMT). Here, we determined the critical molecules involved in autophagy-induced EMT and elucidated the possible mechanism of chemoradiotherapy resistance and tumor recurrence.
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