Publications by authors named "Zhijia Xie"
The diagnosis and treatment of intestinal and urinary tract deep infiltrating endometriosis (DIE) remain challenging due to its multiple lesions and nonspecific symptoms and signs. This study retrospectively analyzed 72 cases of intestinal and urinary tract DIE, including the clinical characteristics, diagnosis, and treatment outcomes. Among these cases, 11 presented without clinical symptoms, while 61 exhibited obvious clinical symptoms, primarily dysmenorrhea (58.
View Article and Find Full Text PDFObjective: To investigate the factors influencing recurrence following laparoscopic conservative surgery in patients with ovarian endometriosis (OEM) and to develop a predictive model.
Methods: In this retrospective study, the clinical data from 212 OEM patients who underwent laparoscopic conservative surgery at Suzhou Ninth People's Hospital from May 2013 to December 2021 were meticulously reviewed. According to disease recurrence over a 2-year follow-up period, the patients were divided into a recurrence group and a non-recurrence group.
Article Synopsis
- Endometriosis is linked to a higher risk of endometrial cancer, but the exact biological mechanisms involved are not yet clear, prompting a study to identify relevant genes and pathways using bioinformatics.
- Researchers analyzed multiple datasets for both endometriosis and endometrial cancer to find differentially expressed genes (DEGs) and conducted various bioinformatics assessments to explore their roles.
- The analysis revealed 141 DEGs shared between the two conditions, highlighting their involvement in growth regulation and specific signaling pathways, with a focus on ten central genes that may serve as potential biomarkers for diagnosis and prognosis.
Background: Cancer/testis antigen-45A1 (CT45A1) is overexpressed in various types of cancer but is not expressed in healthy women. The role of CT45A1 in cervical cancer has not yet been described in the literature.
Purpose: The aim of this research was to study the role of CT45A1 in cervical cancer progression and drug resistance, elucidate the mechanisms underlying CT45A1-mediated tumorigenesis and investigate CT45A1 as a biomarker for cervical cancer diagnosis, prognostic prediction, and targeted therapy.