Tumor detection on bronchoscopic images by unsupervised learning.

The diagnosis and early identification of intratracheal tumors relies on the experience of the operators and the specialists. Operations by physicians with insufficient experience may lead to misdiagnosis or misjudgment of tumors. To address this issue, a datasets for intratracheal tumor detection has been constructed to simulate the diagnostic level of experienced specialists, and a Knowledge Distillation-based Memory Feature Unsupervised Anomaly Detection (KD-MFAD) model was proposed to learn from this simulated experience.

Toxicokinetics and tissue dynamics approaches to evaluate the accumulation and elimination of cadmium in black soldier fly larvae.

The black soldier fly larvae (BSFL) is a highly valued resource insect, renowned for its efficient and eco-friendly approach to the treatment of organic waste. A crucial matter that demands clarification is whether the heavy metals are eliminated or remain within BSFL bodies. Our research focused on the toxicokinetic and the dynamic tissue changes of cadmium (Cd) in BSFL exposed to low (50 mg/kg), moderate (300 mg/kg), and high levels (700 mg/kg) of Cd stress, with the goal of offering a novel perspective on this matter.

Elevated serum IGFBP-1 levels correlate with cognitive deficits in treatment-resistant and chronic medicated schizophrenia patients.

Background: Schizophrenia is a debilitating psychiatric disorder with diverse cognitive impairments. Insulin-like growth factor binding protein 1 (IGFBP-1), a ubiquitous negative regulator of IGF signaling, crosses the blood-brain barrier after peripheral synthesis. Given the crucial role of IGF signaling in cognitive function, we reasoned that altered serum IGFBP-1 concentrations might be associated with cognitive impairments in schizophrenia.

Benefit finding among family caregivers of patients with advanced cancer in a palliative treatment: a qualitative study.

Background: Benefit finding is the search for positive meaning from traumatic events, such as cancer. It can help caregivers have a positive experience in the caregiving process, relieve negative emotions, and reduce caregiving stress. The aim of this study was to explore benefit finding among caregivers of patients with advanced cancer in their palliative caregiving journey.

Association between elevated serum matrix metalloproteinase-2 and tumor necrosis factor-α, and clinical symptoms in male patients with treatment-resistant and chronic medicated schizophrenia.

Background: Inflammation has an important role in the pathogenesis of schizophrenia. The aim of this study was to investigate the levels of tumor necrosis factor (TNF) and matrix metalloproteinase-2 (MMP-2) in male patients with treatment-resistant schizophrenia (TRS) and chronic medicated schizophrenia (CMS), and the relationship with psychopathology.

Methods: The study enrolled 31 TRS and 49 cm male patients, and 53 healthy controls.

A Soft Sensor Model of Sintering Process Quality Index Based on Multi-Source Data Fusion.

In complex industrial processes such as sintering, key quality variables are difficult to measure online and it takes a long time to obtain quality variables through offline testing. Moreover, due to the limitations of testing frequency, quality variable data are too scarce. To solve this problem, this paper proposes a sintering quality prediction model based on multi-source data fusion and introduces video data collected by industrial cameras.

Characterizations and Nonlinear-Optical Properties of Pentanary Transition-Metal Oxysulfide SrCoGeOS.

As one type of material containing multiple anions, oxysulfides can combine the advantages of oxides and sulfides and are deeply studied as nonlinear-optical (NLO) materials. Herein, a new melilite-type pentanary oxysulfide SrCoGeOS is studied. It crystallizes in the noncentrosymmetric tetragonal space group 4̅2, and its structure features GeOS and CoS tetrahedra-built {[CoGeOS]} layers.

Misdiagnosis of primary mucosa-associated lymphoid tissue lymphoma of the pleura: case report and literature review.

Background: Mucosa-associated lymphoid tissue (MALT) lymphoma is an indolent B cell lymphoma. Its occurrence in the pleura is rare, with atypical clinical manifestations. MALT of the pleura is easily misdiagnosed.

Two low-toxic Klebsiella pneumoniae strains from gut of black soldier fly Hermetia illucens are multi-resistance to sulfonamides and cadmium.

In recent years, pollution of antibiotics and heavy metal has often been reported in organic wastes. Saprophytic insects have been recorded as biological control agents in organic waste management. During organic waste conversion, the intestinal bacteria of the saprophytic insects play an important role in digestion, physiology, immunity and prevention of pathogen colonization.

Cation Regulation to Investigate the Chalcogenide Borate RENbMgSBO (RE = La-Nd) Family.

Chalcogenide borates have been developed and are considered an attractive system due to their favorable physical properties such as magnetism and nonlinear optical effects. Here, isostructural RENbMgSBO (RE = La-Nd) compounds in the title family have been obtained through cation regulation in rare-earth and VB group metals. This family crystalizes in the centrosymmetric 3̅ space group and features 3D frameworks formed by {[Mg(NbBO)]} polyanionic layers and QRE octahedra.

Whole Genome Sequencing and RNA-seq-Driven Discovery of New Targets That Affect Carotenoid Synthesis in .

Carotenoids are unsaturated compounds with terpene groups. Among them, astaxanthin has strong antioxidant properties. It is widely used in aquaculture, food, medicine, and cosmetics with a broad market prospect.

Sn Br S : The First Ternary Halogen-Rich Chalcohalide Exhibiting a Chiral Structure and Pronounced Nonlinear Optical Properties.

Infrared nonlinear optical (IR NLO) materials are significant in laser technology for civil and military uses. Here, we report the synthesis, structural chemistry and NLO properties of a halogen-rich chalcohalide Sn Br S . Its noncentrosymmetric (NCS, P6 ) structure can be considered as partially aliovalent anion substitution of SnBr (P6 /m) induced centrosymmetric (CS) to NCS structural transformation.

Second-Harmonic-Generation-Active Oxyhalides: CuSbOX (X = Cl, Br).

Metal oxyhalides have attracted broad interest recently because of their diverse structures and versatile properties. Here, two oxyhalides, CuSbOCl () and CuSbOBr (), were studied by focusing on their nonlinear-optical properties. They are crystallized in the noncentrosymmetric monoclinic structure, and the layered structures could be derived from a 1:1 combination of CuX- (X = Cl, Br) and SbO-type slabs.

SnPQ (Q = S, Se, S/Se): A Series of Lone-Pair Cationic Chalcogenophosphates Exhibiting Balanced NLO Activity Originating from SnQ Units.

Two chalcogenophosphates, SnPSSe () and SnPSe (), are isostructural and crystallize in the monoclinic noncentrosymmetric space group . Their three-dimensional (3D) structures are constructed by [Sn(1)Q] hendecahedra and [Sn(2)Q] dodecahedra by sharing Q vertices and edges, leaving cavities for isolated [PQ] (Q = S/Se, Se) dimers. A second-harmonic-generation (SHG) measurement indicates that is phase-matchable with a response of approximately 1.

Demographic Characteristics and Lifestyle Habits of Chinese Plasma Donors: A Multicenter Study.

BACKGROUND The demand for plasma and plasma products has increased in China, which has a short supply. Compared with whole blood donors, plasma donors and their donation behavior have received less attention. This study aimed to investigate the demographic characteristics and lifestyle habits of Chinese plasma donors.

Identification of three metallothioneins in the black soldier fly and their functions in Cd accumulation and detoxification.

The black soldier fly (BSF) Hermetia illucens has a strong tolerance to cadmium stress. This helps to use BSF in entomoremediation of heavy metal pollution. Rich metallothionein (MT) proteins were thought to be important for some insects to endure the toxicity of heavy metal.

The clinical characteristics of East Asian patients with Birt-Hogg-Dubé syndrome.

Background: Birt-Hogg-Dube (BHD) syndrome is an autosomal dominant disease that has been characterized by skin lesions, multiple pulmonary cysts, spontaneous pneumothorax, and renal tumors, but the patients in Asian countries may show fewer symptoms. We aimed to explore and summarize the clinical features of BHD patients in East Asia to facilitate early diagnosis and timely interventions.

Methods: We collected and analyzed the clinical data of patients diagnosed with BHD in our hospital by reviewing medical records.

Clustering Cases of Chlamydia psittaci Pneumonia in Coronavirus Disease 2019 Screening Ward Staff.

We describe 4 cases of Chlamydia psittaci pneumonia among medical staff in a coronavirus disease 2019 (COVID-19) screening ward, as well as the experience of dealing with this nosocomial infection event. Atypical pneumonia, in addition to COVID-19, should be considered when clustering cases occur, even during a COVID-19 pneumonia pandemic.

Feiyangchangweiyan capsule protects against ulcerative colitis in mice by modulating the OSM/OSMR pathway and improving gut microbiota.

Background: Feiyangchangweiyan capsule (FYC) is a traditional Chinese medicine formulation used in the clinical treatment of acute and chronic gastroenteritis and bacterial dysentery. However, the effect of FYC on ulcerative colitis (UC) and the mechanism thereof remains unknown.

Purpose: To investigate the protective effect of FYC on UC mice induced by dextran sulfate sodium and illustrate the potential mechanism of this effect.

Automatic Identification of Individual Primates with Deep Learning Techniques.

The difficulty of obtaining reliable individual identification of animals has limited researcher's ability to obtain quantitative data to address important ecological, behavioral, and conservation questions. Traditional marking methods placed animals at undue risk. Machine learning approaches for identifying species through analysis of animal images has been proved to be successful.

Attenuation of intermittent hypoxia-induced apoptosis and fibrosis in pulmonary tissues via suppression of ER stress activation.

Background: Obstructive sleep apnea (OSA) is associated with pulmonary fibrosis and endothelial apoptosis in pulmonary tissues. Chronic intermittent hypoxia (IH) is considered to be the primary player in OSA, but the mechanisms underlying its effect on pulmonary tissues are unknown. Endoplasmic reticulum (ER) stress induced by IH treatment plays an important role in accelerating the process of fibrosis and induction of apoptosis.

A Series of Chalcogenide Borates RETaMgQBO (RE = Sm, Eu, Gd; Q = S, Se) Featuring a BO Cluster.

New compounds with multiple anions are receiving increasing interest in view of their diverse structures and physical properties. Here we report four isostructural hexanary RETaMgQBO (RE = Sm, Eu, Gd; Q = S, Se), belonging to the rare chalcogenide borates. Their structures feature an unprecedented [BO] unit comprised of one BO and three BO units.