Publications by authors named "Zhihua Zhao"

Volatile organic compounds (VOCs) constitute key pollutants in the environment, and exposure to them is associated with negative health impacts. The vigilant monitoring of these pernicious VOCs is imperative for their timely detection and for curtailing the likelihood of both immediate and prolonged exposure, thus safeguarding against the deterioration of environmental quality. In this study, porous PtRu nanoalloys are successfully synthesized via a hydrothermal method and innovatively integrated with SnO nanoparticles to significantly enhance the performance of gas sensors.

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The MXene TiCT was synthesized using hydrofluoric acid and an improved multilayer method in this study. Subsequently, a BiO/TiC2T composite material was produced through hydrothermal synthesis. This composite boasts a unique layered structure, offering a large surface area that provides numerous contact and reaction sites, facilitating the adsorption of ammonia on its surface.

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BiS/TiCT nanomaterials were successfully prepared through a simple hydrothermal method. Various methods were used for their characterization, including XRD, XPS, SEM, EDS, and BET, along with testing their gas-sensing properties. The results showed that the response value to 100 ppm ammonia at room temperature reached 107%, which was 14.

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Two-dimensional material (2D material) MXene has great application potential in gas sensors because of its excellent controllable performance and vast specific surface area. In this study, we used a straightforward in-situ electrostatic self-assembly technique to create Fe(OH)3/Ti3C2Tx nanocomposites, which were then used to fabricate gas sensors for ammonia detection at room temperature (25 ℃). Several characterization methods were performed aimed at determining the surface appearance and construction of the nanocomposites, and the sensing characteristics and mechanism were also systematically examined.

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Retinopathy of prematurity (ROP) is a retinopathy caused by abnormal proliferation of blood vessels in premature infants. It can lead to retinal detachment and, in severe cases, blindness, rendering ROP a critical condition. Advances in neonatal medicine have improved survival rates of low birth weight and low gestational age infants.

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Background: Soybean mosaic disease caused by soybean mosaic virus (SMV) is one of the most devastating and widespread diseases in soybean producing areas worldwide. The WRKY transcription factors (TFs) are widely involved in plant development and stress responses. However, the roles of the GmWRKY TFs in resistance to SMV are largely unclear.

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Industrialization and agricultural demand have both improved human life and led to environmental contamination. Especially the discharge of a lot of poisonous and harmful gases, including ammonia, ammonia pollution has become a pressing problem. High concentrations of ammonia can pose significant threats to both the environment and human health.

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Metal oxide semi-conductors are widely applied in various fields due to their low cost, easy processing, and good compatibility with microelectronic technology. In this study, ternary α-FeO/TiO/TiCT nanocomposites were prepared via simple hydrothermal and annealing treatments. The composition, morphology, and crystal structure of the samples were studied using XPS, SEM, EDS, XRD, and multiple other testing methods.

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As parents or legal guardians primarily care for children with asthma, understanding their knowledge, attitudes, and practices (KAP) barriers to treatment and medication adherence is of essential importance. This study aimed to analyze the KAP toward asthma medication and adherence among preschool-aged asthmatic children's parents and explore the factors influencing adherence. This cross-sectional study was conducted between February 2023 and April 2023.

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Flexible foam-based sensors have attracted substantial interest due to their high specific surface area, light weight, superior deformability, and ease of manufacture. However, it is still a challenge to integrate multimodal stimuli-responsiveness, high sensitivity, reliable stability, and good biocompatibility into a single foam sensor. To achieve this, a magnetoresistive foam sensor was fabricated by an in situ freezing-polymerization strategy based on the interpenetrating networks of sodium alginate, poly(vinyl alcohol) in conjunction with glycerol, and physical reinforcement of core-shell bidisperse magnetic particles.

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Functional studies of long noncoding RNAs (lncRNAs) have been hindered by the lack of methods to assess their evolution. Here we present lncRNA Homology Explorer (lncHOME), a computational pipeline that identifies a unique class of long noncoding RNAs (lncRNAs) with conserved genomic locations and patterns of RNA-binding protein (RBP) binding sites (coPARSE-lncRNAs). Remarkably, several hundred human coPARSE-lncRNAs can be evolutionarily traced to zebrafish.

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Background: Calcium (Ca), potassium (K) and magnesium (Mg) may be involved in the occurrence and development of glaucoma by influencing the retinal oxidative stress and regulate blood pressure. However, epidemiological opinions on dietary intake of macroelement related to glaucoma are inconsistent. Herein, this study aims to explore the association between dietary Ca, K, and Mg consumption and glaucoma.

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Background: The present study was conducted to determine the inflammatory response in the lungs of children with Mycoplasma pneumoniae pneumonia (MPP).

Methods: This study retrospectively analyzed cytokine levels, cytological findings, and M. pneumoniae (MP)-DNA level in the bronchoalveolar lavage fluid (BALF) of 96 children with MPP.

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Objectives: Prediction of the efficacy of continuous positive airway pressure (CPAP) on bronchiolitis is necessary for timely treatment. This study aims to establish a nomogram for efficacy of CPAP on bronchiolitis, and compares accuracy with Pediatric Risk of Mortality III (PRISM III), Brighton Pediatric Early Warning Score (Brighton PEWS) and Pediatric Critical Illness Score (PCIS).

Methods: From February 2014 to December 2020, data on children diagnosed with bronchiolitis and treated with CPAP in Chongqing was collected.

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Ammonia (NH) is a common air pollutant and is a biomarker for kidney disease. Therefore, the preparation of ammonia gas sensors with high sensitivity, good selectivity and low operating temperature is of great importance for health protection. Using the electrostatic self-assembly approach, a chemoresistive gas sensor based on Co(OH)/TiCT hybrid material was created in this study.

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The control and understanding of the nucleation and growth of nano-objects are key points for improving and/or considering the new applications of a given material at the nanoscale. Mastering the morphology is essential as the final properties are drastically affected by the size, shape, and surface structure. Yet, a number of challenges remain, including evidencing and understanding the relationship between the experimental parameters of the synthesis and the shape of the nanoparticles.

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Objective: The aim of this study was to investigate the biological effects of occupational extremely low-frequency electromagnetic field (ELF-EMF) exposure on the thyroid gland.

Methods: We conducted a prospective analysis of 85 workers (exposure group) exposed to an ELF-EMF (100 μT, 10-100 Hz) produced by the electromagnetic aircraft launch system and followed up on thyroid function indices, immunological indices, and color Doppler images for 3 years. Additionally, 116 healthy volunteers were randomly selected as controls (control group), the thyroid function of whom was compared to the exposure group.

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Background: The entomopathogenic fungus Beauveria bassiana and the egg parasitoid Trichogramma dendrolimi can both contribute to biological control of the global fruit borer Grapholita molesta. To derive insights for optimizing their combined application in augmentation programs, we assayed fungal pathogenicity to both G. molesta (eggs, larvae and adults) and adult parasitoids, and assessed wasp acquisition and transmission of fungal spores following their emergence from B.

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Energy-absorbing materials with both high absorption capacity and high reusability are ideal candidates for impact protection. Despite great demands, the current designs either exhibit limited energy-absorption capacities or perform well only for one-time usage. Here a new kind of energy-absorbing architected materials is created with both high absorption capacity and superior reusability, reaching 10 kJ kg per cycle for more than 200 cycles, that is, unprecedentedly 2000 kJ kg per lifetime.

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Article Synopsis
  • CaMKII is crucial for synaptic plasticity, and recent studies suggest that various modulators influence its activity, particularly regarding long-term potentiation (LTP) in hippocampal neurons.
  • A new long non-coding RNA named Carip has been identified, which acts as a scaffold that interacts with CaMKIIβ to regulate the phosphorylation of AMPA and NMDA receptor subunits.
  • The absence of Carip disrupts synaptic transmission and reduces LTP, ultimately leading to impairments in spatial learning and memory in mice.
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New Findings: What is the central question of this study? The aim was to investigate the function of brahma-related gene-1 (BRG1) in airway remodelling epithelial-to-mesenchymal transition (EMT) of asthma and identify the transcription factor of BRG1 that binds to the protomer of E-cadherin. What is the main finding and its importance? This study highlighted an important molecular mechanism involving chromatin remodelling factor BRG1 that played a crucial role in airway remodelling EMT of asthma and demonstrated that ZEB1 was the key transcription factor recruiting BRG1. This finding might offer new insights into gene-based therapy for asthma.

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Background: Autoimmune encephalitis (AE) with multiple auto-antibodies is of great clinical significance because its complex clinical manifestations and atypical imaging increase the difficulty of diagnosis, differential diagnosis and treatment, which may aggravate the disease, increase the recurrence rate and mortality. The coexistence of anti-Leucinie-rich Glioma Inactivated 1 (LGI1) and anti-γ-aminobutyric acid-beta-receptor 1 (GABAR1) has not been published before.

Case Presentation: We herein present the case of a 60-year-old man with slow response, behavioral changes, psychosis and sleep disorders.

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Article Synopsis
  • - Strabismus is a common eye condition in children where both eyes do not align properly, which can lead to issues like double vision and affect learning if not treated in time; it often requires surgical intervention due to genetic and neurological causes.
  • - Traditional surgery for strabismus often results in complications due to human error, while the emergence of microsurgical techniques has improved the precision and outcomes of these procedures.
  • - A study found that microsurgery for strabismus in children leads to shorter surgery times, less blood loss, fewer complications, and overall better results, with factors like age and preoperative conditions influencing recovery.
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