Efficacy and risk factors of stent placement in the treatment of malignant tracheoesophageal fistula.

Background: Due to the low incidence of malignant tracheoesophageal fistula and the paucity of relevant clinical studies, the benefits of stent implantation have not been well documented. It remains unclear which factors may affect fistula closure.

Methods: Between January 2015 and January 2021, 344 patients who were diagnosed with malignant tracheoesophageal fistula at Zhongda Hospital, Southeast University, were retrospectively enrolled.

Failure analysis of a rapid quench boiler for ethylene cracker.

The corrosion and leakage issues of rapid quench boilers have become increasingly prominent in ethylene plants, significantly disrupting the regular functioning of equipment. In pursuit of a more efficacious corrosion protection strategy, a study was conducted on the heat exchange tubes experiencing corrosion leakage in the quenching boiler of a petrochemical company. By means of macroscopic observation, chemical composition analysis, mechanical property analysis, metallographic analysis, fracture surface morphology observation, and energy spectrum analysis, combined with on-site process parameters, a comprehensive analysis of the failure causes of the corroded leakage sites was conducted.

Research Progress in Immunotherapy of Gliomas.

Although some progress has been made in tumor treatment, gliomas remain one of the tumors that can still seriously threaten human life and health. Due to the particularity of the immune microenvironment of the central nervous system and the strong invasiveness of tumors, the treatment of gliomas remains a major challenge. Currently, researchers have explored a large number of immunotherapy programs to improve the survival and prognosis of glioma patients, including tumor vaccines, immune checkpoint inhibitors, adoptive cell transfer therapy, viral vector therapy, and genetic engineering therapy.

Design, Synthesis and Fungicidal Activity of Ester Derivatives of 4-(3,4-Dichloroisothiazole) 7-Hydroxy Coumarin.

The development of new fungicides is vital for safeguarding crops and ensuring sustainable agriculture. Building on our previous finding that 4-(3,4-dichloroisothiazole)-7-hydroxy coumarins can be used as fungicidal leads, 44 novel coumarin ester derivatives were designed and synthesized to evaluate whether esterification could enhance their fungicidal activity. In vitro fungicidal bioassays indicated that compound displayed good activity against , , , and , with an EC value ranging from 2.

From part to whole, operative link on to endoscopic grading of gastric intestinal metaplasia, pathology to endoscopy: gastric intestinal metaplasia graded by endoscopy.

To conduct a systematic review and meta-analysis on the prediction of severity of gastric intestinal metaplasia (GIM) in localized and entire gastric mucosa using endoscopy. The authors searched Web of Science, PubMed, Embase and Cochrane Central Register of Controlled Trials and performed systematic searches on endoscopic grading of GIM of the entire stomach using Meta-DiSc and Stata. Sensitivity and specificity for the stratified prediction of overall GIM were 0.

Preparation of SnS/MWCNTs chemically modified electrode and its electrochemical detection of HO.

Considering the importance of hydrogen peroxide (HO) rapid detection, a SnS/MWCNTs composite was prepared by loading tin disulfide (SnS) nanoparticles on a three-dimensional conductive network composed of multi-walled carbon nanotubes (MWCNTs). The obtained SnS/MWCNTs composite was used as the modified material to prepare a chemically modified electrode (CME), which was used for the rapid detection of HO. The morphology and structure of the obtained samples were characterized and analyzed by scanning electron microscopy, X-ray diffraction, and energy-dispersive spectroscopy.

A sustainable process for the recovery of volatile constituents from in agar production and evaluation of their antioxidant activities.

Background: is a common red alga used as a raw material source for the agar industry. Its extract is rich in natural volatile constituents (VCs) having antioxidant activities. Herein, a sustainable method was used to recover VCs from the alga.

Optimization of decolorization process in agar production from and evaluation of antioxidant activities of the extract rich in natural pigments.

is mainly used as a raw material source for agar industry, and its extract is rich in natural pigments with antioxidant activities. In this study, a solvent reflux extraction method for decolorization of has been developed in agar production. The extraction conditions were optimized as follows: solvent-to-material ratio, 50:1; ethanol concentration, 70%; number of extractions, 3; extraction time, 0.

[Chemical constituents from Elsholtzia blanda].

Objective: To investigate the constituents of Elsholtzia blanda.

Method: The chemical components were isolated by polyamide and silica gel column chromatography. Their structures were identified with extensive spectral (EI-MS, ESI-MS, 1H-NMR, 13C-NMR, DEPT, 1H-1H-COSY, HMBC, HMQC) and chemical methods.