Eosinophils and drugs for eosinophilia are associated with the risk of colorectal cancer: a Mendelian randomization study.

Eosinophils have the potential to exhibit both anti-tumor properties and tumor-promoting effects. However, the impact of eosinophil levels in the bloodstream on tumorigenesis risk remains inadequately explored. Furthermore, investigations regarding the association between drugs regulating eosinophils and cancer risk are currently absent.

Amino acids and risk of colon adenocarcinoma: a Mendelian randomization study.

Background: The existence of amino acid metabolic reprogramming in tumor cells is well established. However, the potential correlation between blood amino acids and the risk of colon adenocarcinoma remains largely unexplored.

Methods: We utilized Mendelian randomization (MR) analysis to examine the association between 20 amino acids in the blood and the risk of colon adenocarcinoma.

Thermochromic Photonic Crystal Microspheres with Uniform Color Display and Wide Coloration Range.

Thermochromic microspheres based on poly(N-isopropylacrylamide) attract much attention in detection and sensor due to the noticeable color response and fast response rate. However, some issues such as uneven color display and narrow coloration range still limit their practical applications. Herein, novel thermochromic microspheres with homogeneous color displays and wide thermochromic range are designed by combining the microfluidic technology with the magnetically-induced self-assembly technique and copolymerizing acrylamide (AM) with N-isopropylacrylamide.

Magnetically Assembled Photonic Crystal Gels with Wide Thermochromic Range and High Sensitivity.

Thermochromic poly(N-isopropyl acrylamide) (PNIPAM) photonic crystal gels based on 1D magnetically assembling colloidal nanocrystal clusters have attracted much attention due to its convenient preparation process, striking color response, and good mechanical strength. However, there remain challenges to broaden the thermochromic range and improve the sensitivity for their iridescent color display. Here, a PNIPAM photonic gel with wide thermochromic range and high sensitivity is prepared by using four-arm star poly(ethylene glycol) acrylamide (PEGAAm) as cross-linker at appropriately reduced magnetic field strength as well as cross-linker content.