Cobalt vacancy-originated TiMnCoCN compounds with a self-adjusting ability for the high-efficiency acidic oxygen evolution reaction.

Oxygen evolution reaction (OER) electrocatalysts in acidic media, except for precious IrO, have difficulty realizing good electrocatalytic activity and high electrochemical stability simultaneously. However, the scarcity of IrO as an acidic OER electrocatalyst impedes its large-scale application in hydrogen generation, organic synthesis, nonferrous metal production and sewage disposal. Herein, we report the design and fabrication of a nanoporous TiMnCoCN compound based on the nanoscale Kirkendall effect, possessing an intriguing self-adjusting capability for the oxygen evolution reaction (OER) in a 0.

Strain in a platinum plate induced by an ultrahigh energy laser boosts the hydrogen evolution reaction.

The ligand and the strain near the active sites in catalysts jointly affect the electrocatalytic activity for the catalytic industry. In many cases, there is no effective strategy for the independent study of the strain effect without the ligand effect on the electrocatalytic activity for the hydrogen evolution reaction (HER). Laser shock peening (LSP) with a GW cm level power density and a 10-30 ns short pulse is employed to form compressive strain on the surface and in the depth direction of a platinum (Pt) plate, which changes the inherent interatomic distance and modifies the energy level of the bonded electrons, thereby greatly optimizing the energy barrier for the HER.

Bicontinuous Nanoporous Nitrogen/Carbon-Codoped FeCoNiMg Alloy as a High-Performance Electrode for the Oxygen Evolution Reaction.

The kinetics of the oxygen evolution reaction (OER) in aqueous electrolytes is relatively slow, which seriously limits the energy efficiency of electricity-to-hydrogen conversion. Herein, a bicontinuous nanoporous FeCoNiMg alloy is prepared by high heat sintering method based on the nanoscale Kirkendall effect and the surface is codoped with nitrogen and carbon elements by the nitrocarburizing method (denoted NC-FeCoNiMg). The three-dimensional (3D) nanoporous NC-FeCoNiMg alloy electrode achieves superior electrocatalytic performance for the OER in alkaline media, delivering a low Tafel slope (34.

Self-supported nickel-doped molybdenum carbide nanoflower clusters on carbon fiber paper for an efficient hydrogen evolution reaction.

Developing an efficient, stable and low-cost noble-metal-free electrocatalyst for the hydrogen evolution reaction (HER) is an effective way to alleviate the energy crisis. Herein, we report a simple and facile approach to synthesize self-supported Ni-doped MoC via a molten salt method. By optimizing the content of Ni, the concentration of Ni(NO), and the annealing time, self-supported nanoflower-like electrocatalysts composed of ultrathin nanosheets on carbon fiber paper (CFP) can be achieved.

One-Step and One-Precursor Hydrothermal Synthesis of Carbon Dots with Superior Antibacterial Activity.

Discovering efficient antibacterial materials is crucial in the area of increasing drug resistance. Herein, we synthesized carbon dots (C-dots) with superior antibacterial activity through a simple one-step hydrothermal method. In this method, -phenylenediamine serves as not only the carbon source but also the origin for the functional group anchored on the obtained C-dots.

Enhanced mechanical properties of 4H-SiC by epitaxial carbon films obtained from bilayer graphene.

Graphene exhibits excellent mechanical properties under atomically thin thickness, which made it very suitable for nanoelectromechanical systems that had high requirements for the thickness of coatings. The epitaxial bilayer graphene on the 4H-SiC (0001) surface presents high stiffness and hardness comparable to diamond. However, due to structural transition occurring at the nanoscale, it is difficult to elucidate reinforcement mechanisms using experimental methods.

Cobalt-Iron Oxide Nanoarrays Supported on Carbon Fiber Paper with High Stability for Electrochemical Oxygen Evolution at Large Current Densities.

Here, we demonstrate that nonprecious CoFe-based oxide nanoarrays exhibit excellent electrocatalytic activity and superior stability for electrochemical oxygen evolution reaction (OER) at large current densities (>500 mA cm). Carbon fiber paper (CFP) with three-dimensional macroporous structure, excellent corrosion resistance, and high electrical properties is used as the support material to prevent surface passivation during the long-term process of OER. Through a facile method of hydrothermal synthesis and thermal treatment, vertically aligned arrays of spinel Co FeO nanostructures are homogeneously grown on CFP.

Morphology-Controllable Synthesis of Cobalt Telluride Branched Nanostructures on Carbon Fiber Paper as Electrocatalysts for Hydrogen Evolution Reaction.

Cobalt telluride branched nanostructures on carbon fiber paper (CFP) with two different morphologies were synthesized via solution-based conversion reaction. Both the CoTe2 with nanodendrite and CoTe with nanosheet morphologies on the CoTe2 nanotube (CoTe2 NDs/CoTe2 NTs and CoTe NSs/CoTe2 NTs) supported by CFP exhibit high activities toward hydrogen evolution reaction (HER). Particularly, the CoTe NSs/CoTe2 NTs only require an overpotential of 230.

Endothelium-dependent and -independent vasorelaxant actions and mechanisms induced by total flavonoids of Elsholtzia splendens in rat aortas.

Elsholtzia splendens (ES) is, rich in flavonoids, used to repair copper contaminated soil in China, which has been reported to benefit cardiovascular systems as folk medicine. However, few direct evidences have been found to clarify the vasorelaxation effect of total flavonoids of ES (TFES). The vasoactive effect of TFES and its underlying mechanisms in rat thoracic aortas were investigated using the organ bath system.

[Effects of total flavones of Elsholtzia splendens in isolated ischemia/reperfusion rat hearts].

Objective: To investigate the influence of total flavonoids of Elsholtzia splendens (TFES) on isolated ischemia/reperfusion rat hearts and its underlying mechanisms.

Methods: Hearts isolated from male SD rats were perfused on the Langendorff apparatus and subjected to global ischemia for 30 min followed by 120 min of reperfusion. The cardiac infarct size was measured by TTC staining.

[Luteolin reduces cardiac dysfunctions in streptozotocin-induced diabetic rats].

Objective: To investigate the effects of luteolin (Chinese Traditional Medicine) on cardiac functions and mitochondrial oxidative stress in streptozotocin (STZ)-induced diabetic rats.

Methods: Male SD rats were randomly divided into a normal control group, a luteolin control group, a diabetic group, and diabetic groups orally administered with a low dose (10 mg/(kg x d)) or a high dose of luteolin (100 mg/ (kg x d)) for eight weeks. The body weight, blood glucose, cardiac functions, left ventricular weight, myocardial collagen and reactive oxygen species (ROS) levels were assayed.

[Expression and function of autophagy after ischemia/reperfusion in rats hippocampus neuron].

Objective: To explore the expression of autophagy after ischemia/reperfusion and its possible function in rats hippocampus neurons.

Methods: After 2 hours oxygen-glucose deprivation and different periods time of reperfusion (OGD/R) treatment in primary hippocampal neurons, neuron viability was evaluated by MTT assay, specific structure of autophagosome and specific protein of autophagy microtubule-associated protein 1 light chain 3 B (LC3B) were detected by transmission electron microscope and immunofluorescence respectively. The inhibitor of autophagy 3-Methyladenine (3-MA) was also used to exam the viability of neurons.

[Effect of S-allyl-L-cysteine on isolate heart subject to ischemia/reperfusion].

Objective: To investigate the effect of S-allyl-L-cysteine (SAC) on isolated rat heart subject to ischemia/reperfusion(I/R) injury and the mechanisms.

Methods: The isolated perfused rat hearts on a Langendorff apparatus were subjected to global ischemia for 30 min and followed by 120 min of reperfusion. Hemodynamic index, the production of formazan and the level of lactate dehydrogenase (LDH) in the coronary effluent were determined.

[Study of the effects of Auricularia auricular polysaccharide on local ischemia/reperfusion injury in rat].

Objective: To investigate the influence of Auricularia Auricular polysaccharide (APP) on acute cerebral injury induced by ischemia/reperfusion in rats and its underlying mechanism.

Methods: Adult male SD rats were intragastrically pretreated with AAP at a low (50 mg/kg) or high (100 mg/kg) dose once a day for 20 days before operation. Rats intraperitoneally injected with ginkgo biloba extract (EGb671) were taken as positive control.

[Electrophysiological effect of atorvastatin on isolated rat hearts injured by ischemia/reperfusion].

Objective: To investigate the myocardial electrophysiological effect and its underlying mechanisms of atorvastatin (Ator) on isolated rat hearts injured by ischemia/reperfusion (I/R).

Methods: Isolated SD rat hearts were mounted on Langendorff system, and a local I/R was induced by ligation (30 min) and release (15 min) of the left anterior descending artery. During the reperfusion period, the effect of Ator on diastolic excitation threshold (DET), effective refractory period (ERP) and ventricular fibrillation threshold (VFT) on rat heart were measured.

[Partial endothelium-dependent vasorelaxation of crocetin and its mechanism].

Objective: To investigate the vasorelaxation effect of crocetin (CCT) and its mechanism.

Methods: Isolated aortic rings from Sprague-Dawley rats were mounted in the organ bath system. The tension of the aorta was recorded.

[Auricularia auricular polysaccharide protects myocardium against ischemia/reperfusion injury].

Objective: To determine whether auricularia auricular polysaccharide (AAP) protects heart against ischemia/reperfusion (1/ R) injury and its underlying mechanisms.

Methods: Male Sprague-Dawley rats, pretreated with AAP (50, 100, 200 mg/(kg x d), gastric perfusion) for 4 weeks, were used for Langendorff isolated heart perfusion. The hearts were subjected to global ischemia for 30 min followed by 120 min of reperfusion and the left ventricular hemodynamic parameters were measured.

[Myocardial protective effect of acetylcholine against ischemia/reperfusion injury and its underlying mechanism].

Objective: To determine whether the caidioprotection of acetylcholine (ACh) against ischeniia/reperftision (I/R) injury is re-kited to mitochondrial permeability transition pore (MEW) and mitochondrial AW-sensitive potassium channel (mitoK(ATP)).

Methods: Male Sprague-Dawley rats were used for Langendorif isolated bean perkision. The hearts were subjected to global ischemia for 30 mm followed by 120 rein of reperfusion and the left ventricular hemodynaniic parameters were measured.

Mitochondrial pores modulate the protective effect of acetylcholine on ventricular myocytes during ischemia/reperfusion injury.

In this study, we investigated the cardioprotective effect of acetylcholine (ACh) via modulation of mitochondrial permeability transition pore (MPTP) opening through the mitochondrial ATP-sensitive potassium channel (mitoK(ATP) channel). In isolated ventricular myocytes from male Sprague-Dawley rats, 0.1 micromol/L ACh was administered for 6 min, before 30 min of simulated ischemia and 30 min of reperfusion (I/R).

[Antiarrhythmic effect of ethyl acetate extract from Chrysanthemum Morifolium Ramat on rats].

Objective: To investigate the effect of ethyl acetate extract from Chrysanthemum Morifolium Ramat (CME) on experimental arrhythmia induced by ischemia/reperfusion or aconitine in rats and to explore its underlying mechanisms.

Methods: Arrhythmia model in intact rat was induced by aconitine (30 microg/kg body weight, i.v.

[Effect of gap junction on the cardioprotection of ischemic postconditioning in rat heart].

Aim: To determine whether the cardioprotection of ischemic postconditioning and heptanol in ischemic heart against ischemia/reperfusion (I/R) is mediated by gap junction.

Methods: The effect of ischemic postconditioning, heptanol at different doses (0.03, 0.

[Superoxide anion inhibit endothelium-dependent relaxation in rat mesenteric artery].

Aim: To explore the resistant arterial effect of superoxide anion and its possible mechanisms.

Methods: The third branch of the superior mesenteric artery in male Sprague-Dawley (200-300 g) rats was rapidly excised. Periadventitial fats and connective tissues were removed and the artery was dissected into about 2 mm rings.

Inhibition of superoxide anion-mediated impairment of endothelium by treatment with luteolin and apigenin in rat mesenteric artery.

This study was designed (i) to test the hypothesis that the endothelium-derived hyperpolarizing factor (EDHF) component of ACh-induced vasorelaxation and hyperpolarization of smooth muscle cells (SMCs) are impaired following exposure to superoxide anion, and (ii) to further investigate whether luteolin and apigenin induce vasoprotection at the vasoactive concentrations in rat mesenteric artery. Rat mesenteric arterial rings were isolated for isometric force recording and electrophysiological studies. Perfusion pressure of mesenteric arterial bed was measured and visualization of superoxide production was detected with fluorescent dye.

Ischemic postconditioning protects against global cerebral ischemia/reperfusion-induced injury in rats.

Background And Purpose: Ischemic postconditioning has been found to decrease brain infarct area and spinal cord ischemic injury. In this study, we tested the hypothesis that ischemic postconditioning reduces global cerebral ischemia/reperfusion-induced structural and functional injury in rats.

Methods: Ten-minute global ischemia was induced by 4-vessel occlusion in male Sprague-Dawley rats.

Opening the calcium-activated potassium channel participates in the cardioprotective effect of puerarin.

The aim of the present study was to determine whether the effective cardioprotection conferred by puerarin against ischemia and reperfusion is mediated by the calcium-activated potassium channel. Hearts isolated from male Sprague-Dawley rats were perfused on a Langendorff apparatus and subjected to 30 min of global ischemia followed by 120 min of reperfusion. The production of formazan, which provides an index of myocardial viability, was measured by absorbance at 550 nm, and the level of lactate dehydrogenase (LDH) in the coronary effluent was determined.