Silencing of circCDC14A prevents cerebral ischemia-reperfusion injury via miR-23a-3p/CXCL12 axis.

Ischemic stroke is one of the main causes of death and disability. Circular RNAs (circRNAs) have received extensive attention in the pathogenesis of ischemic stroke. Here, we evaluated the role of circCDC14A in cerebral ischemia-reperfusion (CI/R) injury in vivo and in vitro.

[Risk factors for congenital anal atresia].

Objective: To investigate the risk factors for the development of congenital anal atresia in neonates.

Methods: A total of 70 neonates who were admitted to 17 hospitals in Foshan, China from January 2011 to December 2014 were enrolled as case group, and another 70 neonates who were hospitalized during the same period and had no anal atresia or other severe deformities were enrolled as control group. Univariate and multivariate logistic regression analyses were used to investigate the risk factors for the development of congenital anal atresia.

[Clinical feature of severe hand, foot and mouth disease with acute pulmonary edema in pediatric patients].

Objective: To explore the clinical feature of severe hand, foot and mouth disease (HFMD) in pediatric patients, and to observe the hemodynamic changes in those with acute pulmonary edema.

Methods: A prospective observation study was conducted. Thirty-five severe HFMD pediatric patients with acute pulmonary edema admitted to the intensive care unit (ICU) and Department of Pediatric of First People's Hospital of Foshan from May 2008 to September 2014 were enrolled.

[Effect of TFCC on proliferation of the first trimester human cytotrophoblast and its possible signal transduction pathway].

Objective: To investigate the effect of total flavones from Cuscuta chinens is (TFCC) on proliferation of the first trimester human cytotrophoblast and its possible signal transduction pathway.

Methods: The first trimester human trophoblast cells were isolated by trypsin/Dnasel digestion and discontinuous Percoll density gradient centrifugation. After identified by immunocytochemistry to Cytokeratin 7 and Vimentin, the trophoblast cells appared to more than 95% pure.