Publications by authors named "Zhigao Sun"

Background: Sleep disturbance is an immune-related disease, and the gut-brain axis is an important regulatory pathway. This cross-sectional study was designed to address these associations between complement C4, habitual constipation, and sleep disturbance and presents a reference for prevention and treatment of sleep disturbance.

Methods: Based on the China Hainan Centenarian Cohort Study, Pittsburgh Sleep Quality Index (PSQI) was used to evaluate sleep disturbance following standard procedure.

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Background: Sarcopenia is an aging-related disorder characterized by a loss of muscle mass and function. Calf circumference (CC) is a useful surrogate marker of muscle mass and function. This prospective study was designed to investigate the association between CC and all-cause mortality during a follow-up for 5 years in the Chinese centenarians.

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Soil dissolved organic matter (DOM) is the most reactive pool in estuarine marshes, playing an important role in the biogeochemical processes of biogenetic elements. To investigate the impacts of enhanced nitrogen (N) load on DOM molecular composition and its interactions with microbes in typical Cyperus malaccensis mashes of the Min River estuary, a field N load experiment with four N levels (0, 37.50, 50 and 100 g exogenous N m yr, respectively; applied monthly for a total of seven months) was performed.

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To investigate the impacts of spatial expansion by Phragmites australis on spatiotemporal variations of sulfur (S) fractions in marsh soils of the Min River estuary (Southeast China), the contents of total sulfur (TS) and inorganic sulfur (IS) fractions (Water-Soluble-S, W-S-S; Adsorbed-S, A-S; HCl-Soluble-S, H-S-S; and HCl-Volatile-S, H-V-S) were determined in soils of Cyperus malaccensis marsh (before expansion, BE stage), P. australis-C. malaccensis marsh (during expansion, DE stage) and P.

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Citrus peel polyphenols have possess the distinct anti-inflammatory activities. However, its underlying mechanism on ulcerative colitis have not been elucidated. The aim of this research was to investigate the anti-inflammatory effect and action mechanisms of citrus peel polyphenols.

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Objective: Menstrual lifespan (ML) is an important biological characteristic for women. Rare evidence has established the associations between menopause age (MI), geriatric depression and healthy longevity. This study aimed to address these associations in Chinese oldest-old and centenarian women, and explore their related factors in order to provide strategy support for healthy aging.

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Background: Depressive disorder is a common comorbidity in patients with cardiovascular diseases and is associated with increased hospitalization and death rates. The relationships between cardiac structure and function and depressive disorder remains unclear in the older adults, especially in centenarians. Therefore, this study aimed to explore the possible associations between cardiac structure and function and depressive disorder among centenarians.

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Objectives: Depression is a common disease of elderly population, with a global prevalence of more than 20%. Few studies have involved the associations of constipation and overeating with depression, especially in the elderly population. We aimed to address these associations in Chinese oldest-old and centenarians.

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The Spartina alterniflora started to invade the Min River estuary (Southeast China) in 2002 and, thereafter, its invasion area showed an increasing trend. Since the siltation depths caused by S. alterniflora in the Min River estuary were much higher (4.

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To explore the differences in structure and diversity of -type denitrifying microbial community in marsh soils at different invasion stages of , the mudflat (MF, before invasion) and the marsh after seaward invasion for 1-2 years (SAN) and 6-7 years (SA) in Shanyutan of the Minjiang River estuary were investigated by high-through put sequencing method. Results showed that the seaward invasion of reduced the richness and diversity of -type denitrifying microbial community in marsh soils. The -type denitrifying microbial community in soils at different invasion stages included Proteobacteria and Actinobacteria, with Proteobacteria as the dominant one.

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Background: Age-related cognitive decline (ARCD) is a common condition among older adults, affecting 100 million people worldwide. Traditional Chinese Medicine's (TCM) constitution is closely related to the occurrence and development of diseases in the elderly population. However, little is known about the relationships between TCM constitution and ARCD in the super-aged population.

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Background: Depression is considered to be an immune-related disease; however, previous studies have focused on inflammatory factors, and there is no conclusive conclusion on the relationships between immunoglobulins and depression. Therefore, the objective of this cross-sectional study was to evaluate the associations between immunoglobulins and depressive symptoms in Chinese older adults.

Results: The China Hainan Centenarian Cohort Study (CHCCS) provides a significant population-based sample of older adults in Hainan, China.

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To explore the pollution levels, sources and risks of heavy metals in sediments in Fuzhou reach of the Min River, the sediments involving in seven marsh types were sampled. Results showed that the concentrations of Pb, Zn and Cd in sediments declined from freshwater segment to estuarine segment. Higher levels of Cu, Cr and Ni in sediments generally occurred in estuarine segment.

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We examined the effects of invasion on phosphorus forms of marsh soils, based on the method of space-for-time substitution by selecting marshes with different invasion years (SA, 5-6 years; SA, 8-10 years; and SA, 12-14 years) in Shanyutan of the Minjiang River estuary. The results showed that in marsh soils of different invasion years, the proportion of hardly decomposable phosphorus (HCl-Pi and Residual-P) was the highest (46.4%-46.

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Sulfur oxidation-reduction process (SORP) in marsh soil is an important link in sulfur cycle, which plays an important role in maintaining the stability and health of marsh. We summarized the SORP in marsh soil and its influencing factors, and analyzed the research progress of its coupling effects with other elements. The influencing factors of SORP in marsh soil mainly involved biotic (plants, microorganisms, zoobenthos, human activities, .

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To explore the effects of exogenous nitrogen (N) import on decomposition of Suaeda salsa in coastal marsh of the Yellow River estuary, the decomposition rates and the variations of nutrient (C, N, P, and S) in decomposing litters were investigated from May 2014 to November 2015. The in situ experiment included four N addition treatments: N0 (no N import treatment, 0 g N·m·year), Nlow (low N import treatment, 3.0 g N·m·year), Nmedium (medium N import treatment, 6.

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To investigate the distributions and stocks of total phosphorus (TP) in plant-soil systems of marshes in Shanyutan of the Minjiang River estuary and explore its influencing factors, (PA) marsh and (CM) marsh before spatial expansion and ecotonal marsh (EM, and in EM were denoted by PA' and CM', respectively) during spatial expansion were studied. Results showed that, as affected by spatial expansion, the contents of TP in both plant and soil in different marshes showed great variations. Compared with PA and CM marshes, soil TP in EM increased by 20.

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Artificial islands construction can significantly influence the spatial distribution of heavy metals in inshore sediments. In this study, the distribution and contamination of heavy metals (Cd, Co, Cr, Cu, Ni, Pb, Zn, As and Hg) in inshore sediments of the Longkou Bay and artificial island adjacent areas were investigated in 2013 and 2014, respectively. Results showed that the contents of heavy metals increased in the Longkou Bay and decreased in the west of the artificial island in 2014 compared with 2013.

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Objective: Propofol is one of the most commonly used intravenous drugs to induce and maintain general anesthesia. In vivo and in vitro studies have shown that propofol can affect neuronal growth, leading to apoptosis and impairing cognitive function. The Abelson nonreceptor tyrosine kinase (c-Abl) is associated with both neuritic plaques and neurofibrillary tangles in the brains of patients with Alzheimer's disease and other neurodegenerative diseases.

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Objective: To observe the effects of the Bupi Hewei (BPHW) decoction on diarrhea and intestinal flora disorder induced by 5-fluorouracil (5-FU) and investigate the possible mechanism underlying these actions.

Methods: Thirty-five male Sprague-Dawley rats were randomly divided into four groups: normal control, 5-FU, 5-FU + BPHW decoction (10.5 g/kg for 5 consecutive days), and 5-FU + Bacillus licheniformis capsule groups (0.

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BuPiHeWei (BPHW) decoction, a classic Traditional Chinese Medicinal (TCM) prescription, has been widely used in clinical practice to relieve digestive symptoms caused by chemotherapy, such as diarrhea and vomiting. The present study aimed to investigate whether BPHW decoction exerted a protective role in the 5-Fu-induced intestinal mucosal injury in the rats by regulating the mechanisms of TLR-4/NF-B signaling pathway. There were 35 Sprague Dawley rats randomly divided into four groups: normal control group, 5-Fu group, 5-Fu + BPHW decoction group (10.

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To investigate the effects of spatial expansion between native invasive species (Phragmites australis) and commom native species (Cyperus malaccensis) on variations of micro-elements (Pb, Cr, Cu, Zn, Ni, Cd and As) in decomposing litters in the Min River estuary, in situ filed decomposition experiment was conducted in P. australis (PA) community (before expansion, BE), C. malaccensis (CM) community (before expansion, BE) and P.

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To explore the effects of Spartina alterniflora invasion in a seaward direction on variations of inorganic sulfur forms in marsh soils, the levels of inorganic sulfur forms (HO-S, Adsorbed-S, HCl-Soluble-S and HCl-Volatile-S) were determined in bare flat (BF, before invasion), S. alterniflora marsh after seaward invasion for one year (SA') and S. alterniflora marsh after seaward invasion for three years (SA) in Shanyutan of the Minjiang River estuary with the method of space-for-time substitution.

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Silica (Si) is a basic nutrient requirement for many aquatic organisms and its biogeochemical cycle plays an important role in estuarine coastal ecosystems. However, little is known about the role Si plays during plant-plant interactive processes in the marsh ecosystems. Here, variations in biomass, biogenic silica (BSi) content, and available Si content of -dominated marshes, -dominated marshes, and their ecotonal marshes were studied in the Shanyutan marsh in the Min River estuary, China.

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Article Synopsis
  • Understanding nitrogen distribution and processes in intertidal flats can enhance predictions for climate adaptation strategies.
  • The study utilized a space-for-time substitution method to examine nitrogen pools and processes along hydrological gradients, revealing complex interactions between surface and subsurface sediments.
  • Results indicated that rising water levels could lead to decreased nitrogen storage and change the role of ammonium fluxes from a nitrogen sink to a source in these ecosystems.
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