Synopsis of recent research by authors named "Zhifu Han"
- Zhifu Han's research predominantly focuses on the mechanisms of plant immunity, specifically through the study of nucleotide-binding leucine-rich repeat (NLR) proteins and their role in recognizing pathogen effectors and regulating immune responses.
- Recent studies highlight key findings such as the structural basis of autoinhibition in plant NLR proteins, the activation of TIR domain proteins through substrate-induced condensation, and the hijacking of pathogen virulence factors to trigger immune responses, emphasizing the complexity and efficiency of plant immune signaling pathways.
- Han's work also explores the broader implications of TIR domain signaling and its enzymatic activities, detailing how these mechanisms contribute to plant resistance against various pathogens, thus advancing our understanding of plant defense strategies.