Efficacy of Qiancao () and Haipiaoxiao (), a traditional Chinese herb pair, on abnormal uterine bleeding in rats with incomplete abortion.

Objective: To investigate the most effective weight ratio of Qiancao () and Haipiaoxiao () used to produce decoction for the treatment of abnormal uterine bleeding (AUB) in rats with incomplete abortion, and to study the possible mechanism.

Methods: The models of AUB were established by incomplete drug abortion with mifepristone and misoprostol in pregnant rats. The therapeutic effects of decoctions made by eight different weight ratios of Qiancao () and Haipiaoxiao () were observed.

Pretreatment with Jieduxiezhuo decoction impedes elevations in serum uric acid levels in mice.

Objective: To investigate whether Jieduxiezhuo decoction (JDXZD) can prevent serum uric acid elevations in mice.

Methods: Hyperuricemia in mice was induced by intraperitoneally administering uric acid (250 mg/ kg). Concentrations of uric acid in serum were determined using the uric acid enzyme method.

Study of pharmacokinetics and tissue distribution of liposomal brucine for dermal administration.

Objective: To evaluate the pharmacokinetics and tissue distribution of liposomal brucine (LB) for dermal application.

Methods: Pharmacokinetics and tissue distribution were studied by in vivo animal testing. High performance liquid chromatography (HPLC) was used to detect the concentration of brucine in rats' skin, plasma and various tissues.