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Publications by authors named "Zhichao Yue"

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Synopsis of recent research by authors named "Zhichao Yue"

  • Zhichao Yue's recent research focuses on the roles of transient receptor potential melastatin 2 (TRPM2) in ischemic stroke, demonstrating its involvement in excitotoxicity and blood-brain barrier degradation during ischemic events.
  • Findings reveal that TRPM2 interacts with protein kinase Cγ (PKCγ) and that disrupting this interaction can alleviate neuronal damage caused by NMDA receptor activation, offering a potential therapeutic strategy.
  • Additionally, Yue's studies investigate TRPM2's role in atherosclerosis, identifying the TRPM2-CD36 inflammatory axis in macrophages as a protective mechanism against this condition.

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