Publications by authors named "Zhibo Yin"

Background: This study aims to study the possible action mechanism of T-cell immunoglobulin and mucin domain 3 (TIM3) on the migratory and invasive abilities of thyroid carcinoma (TC) cells.

Methods: GSE104005 and GSE138198 datasets were downloaded from the GEO database for identifying differentially expressed genes (DEGs). Functional enrichment analysis and protein-protein interaction (PPI) analysis were performed on the common DEGs in GSE104005 and GSE138198 datasets.

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Background: Myopia is associated with scleral weakness and thinness, leading to visual impairment. Currently, posterior scleral reinforcement (PSR) remains the primary treatment for this condition. However, clinical practice commonly faces challenges such as insufficient donor availability and inadequate strength of allogeneic sclera materials.

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Article Synopsis
  • - The study explores how proximity to a magnetic material can effectively break valley degeneracy in transition-metal dichalcogenides, specifically in a MoS/CrI heterostructure.
  • - Through first-principles calculations, the researchers find that applying a vertical electric field of 0.115 V/Å can produce a significant valley splitting of about 19.60 meV, akin to an external magnetic field of 89.0 T.
  • - The research highlights that changes in valley splitting are influenced by the electric field and interlayer distance, contributing to a better understanding of the magnetic proximity effect and orbital hybridization in two-dimensional materials.
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The van der Waals ferromagnetic material VIis a magnetic Mott insulator. In this work, we investigate the effects of isotropic and anisotropic pressure on the atomic structure and the electronic structure of VIusing the first-principles method. The in-plane strain induces structural distortion and breaks the three-fold rotational symmetry of the lattice.

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  • Researchers have developed a new large chiral nanographene called double π-extended undecabenzo[7]helicene 1, made up of 65 fused rings and 186 carbon atoms.
  • The structure of the nanographene has been confirmed using single crystal X-ray diffraction, and it exhibits a notable absorption of light across a wide spectrum, with an impressive molar absorption coefficient of 844,000 M cm at 573 nm.
  • In addition, this molecule demonstrates a record high intensity of electronic circular dichroism in the visible range, significantly surpassing that of a related mono-undecabenzo[7]helicene derivative.
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Herein we present the first hexapole [9]helicene (H9H). Co-catalyzed [2+2+2] cyclotrimerization of a dinaphthopyrene (DNP) functionalized alkyne provides the hexaaryl benzene precursor 2, which is transformed into H9H via a dehydrocyclization reaction. Formation of each embedded [9]helicene involves forging of a new C-C bond, which stitches together two [4]helicene subunits of the neighboring DNP blades, reminiscent of the initial method Martin developed for the preparation of [9]helicene in the 1960s.

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Synopsis of recent research by authors named "Zhibo Yin"

  • - Zhibo Yin's recent research encompasses diverse areas in biomedical and materials science, focusing on the mechanisms of cancer invasiveness, myopia treatment, and the properties of novel materials including 2D magnetic structures and large carbon nanostructures.
  • - In his 2024 study on thyroid tumors, Yin reveals that TIM3 activation influences the ERK1/2 pathway, enhancing the migratory and invasive capabilities of thyroid carcinoma cells through detailed gene expression analysis.
  • - His work also includes investigations of the biomechanical properties after posterior scleral reinforcement for myopia treatment, along with contributions to the field of nanotechnology through the synthesis and study of unique molecular structures such as helicenes and their physical properties under varying conditions.