Time of Liver Function Abnormal Identification on Prediction of the Risk of Anti-tuberculosis-induced Liver Injury.

Background And Aims: Anti-tuberculosis (anti-TB) drug-induced liver injury (AT-DILI) is the most common side effect in patients who received anti-TB therapy. AT-DILI management includes monitoring liver function until symptoms arise in patients without high-risk factors for liver damage. The present study aimed to investigate the effect of liver function test (LFT) abnormal identification on the risk of DILI, including liver failure and anti-TB drug resistance in patients without high-risk factors.

What is the spatiotemporal relationship between urbanization and ecosystem services? A case from 110 cities in the Yangtze River Economic Belt, China.

Rapid urbanization has altered landscape patterns and ecological functions, causing a decline in ecosystem service and generating many ecological and environmental issues. Studying the spatiotemporal interaction between urbanization and ecosystem service (ES) can provide effective supports for regional sustainability and policy formulation. This research utilizes the Yangtze River Economic Belt (YREB) as a case to analyze the spatiotemporal interaction between multi-urbanization indicators and multi-ESs over a large-scale region.

[Palatal fistula rate after Huaxi Sommerlad-Furlow palatoplasty].

Objective: This study aimed to determine the palatal fistula rate, explore the influencing factors of Huaxi Sommerlad-Furlow (SF) palatoplasty.

Methods: A retrospective review of 385 consecutive cleft-palate cases was performed to determine the incidence of postoperative fistula and assess the possible contributing factors, such as sex, weight, age, cleft type, operator skills, preoperative white blood cell, preventive antibiotic use, and postoperative temperature.

Results: Fistulas occurred in 15/385 patients (3.

Oridonin promotes G2/M arrest in A549 cells by facilitating ATM activation.

Previous studies have demonstrated that oridonin, a tetracyclic diterpenoid compound extracted from Rabdosia rubescens, inhibits proliferation and induces apoptosis in several tumor cell lines. However, the mechanism by which oridonin inhibits the cell cycle remains poorly understood. In the present study, possible mechanisms by which oridonin affects cell cycle progression were explored in A549 lung cancer cells.

Expression of cyclooxygenase-2 and clinicopathologic features in human gastric adenocarcinoma.

Aim: To study the expression of cyclooxygenase-2 (COX-2) gene in gastric cancer and the relationship between COX-2 expression and clinicopathologic features of gastric cancer.

Methods: With reference to the expression of beta-actin gene, COX-2 mRNA level was examined in cancerous tissues and adjacent noncancerous mucosa from 33 patients by semiquantitative reverse transcription-polymerase chain reaction (RT-PCR). Quantitation of relative band Adj volume counts was performed using molecular Analyst for windows software.