NLRP3 mediates trophoblastic inflammasome activation and protects against infection during pregnancy.

Background: Intrauterine () infections pose a major threat during pregnancy via affecting placental immune responses. However, the underlying mechanisms of placental defense against this pathogen remain ill-defined. Therefore, this study aims to investigate the function and the mechanism of inflammasomes on against infection during pregnancy.

Transitional ankle fracture management using a new joystick technique.

Purpose: To investigate the feasibility and short-term clinical efficacy of the arthrography-assisted joystick technique for the treatment of adolescent transitional ankle fracture.

Methods: A retrospective analysis was performed in 10 adolescent transitional ankle fracture patients treated with the arthrography-assisted joystick technology. There were 7 male patients and 3 female patients with a mean age of 12.

[Cytogenetic and molecular characterization of partial trisomy 4q and partial monosomy 10q in a patient].

Objective: To ascertain the karyotype of a girl with moderate mental retardation and growth retardation, perform correlation analysis between chromosomal variation and phenotype, and investigate the application and superiority of array-based comparative genomic hybridization (array-CGH) in clinical cytogenetic diagnosis.

Methods: G-banded chromosome analysis, array-CGH, fluorescence in situ hybridization (FISH) and real-time quantitative PCR (RQ-PCR) were used to ascertain the karyotype of the patient and her relatives.

Results: G-banding analysis of the patient showed a derivative chromosome 10 with an extra fragment on its long arm terminal, both her father and grandmother had an apparently balanced translocation t(4;10)(q25;q26).

[Synthesis of PANI/TiO3 nanorods composites by reverse micelle template and their properties].

PANI/TiO2 nano-composites with different amount of nanometer TiOz were synthesized by using reverse micelle formed from cationic surfactant cetyltrimethyl ammonium bromide (CTAB) as the template. The structure and properties of PANI/TiO2 nano-composites were investigated by FTIR, UV-Vis, TG, TEM and photoluminescence spectroscopy. The self-assembly mechanism of PANI/TiO2 nanorods composites in reversed micelle was discussed briefly.

[Identification of a novel candidate gene KLRC1 within the putative susceptibility locus for systemic lupus erythematosus at 12p12.3-13.2 in a Chinese cohort].

Objective: To identify the candidate genes within the putative susceptibility locus for systemic lupus erythematosus (SLE) at 12p12.3-13.2.