Plant Biotechnol J
January 2025
Dwarf plant architecture facilitates dense planting, and increased planting densities boost the maize yield. However, breeding applications of dwarfing materials for maize are currently limited. There is an urgent need remove the obstacles to applying dwarf resources.
View Article and Find Full Text PDFTo determine the grasshopper species composition, altitudinal distribution patterns, and their main drivers, we conducted a study in Xizang using 33 sample plots ranging from 600 to 4100 m. Grasshoppers were collected from August to October during 2020-2022 using sweep nets. A total of 1159 grasshoppers from six families, 28 genera, and 44 species were identified, with and as the dominant species, comprising 30.
View Article and Find Full Text PDFBackground: Hepatocellular carcinoma (HCC) remains a leading cause of cancer-related mortality, underscoring the need for novel therapeutic targets. This study aimed to elucidate the role of endoplasmic reticulum membrane protein complex subunit 1 (EMC1) in HCC progression and its therapeutic potential.
Methods: Publicly available sequencing data and biopsy specimens were analyzed to assess EMC's clinical value and functions in HCC.
Medicine (Baltimore)
August 2024
Incidence rates of liver cancer have increased worldwide in recent decades, making it a major public health problem globally. Obesity can be caused by multiple factors and promotes the development of liver cancer in many ways. Although the research on the association between obesity and liver cancer was previously explored, we first employed bibliometrics to analyze the current research status.
View Article and Find Full Text PDFMagnesium slag-based porous materials (MSBPM) were successfully synthesized using alkali activation and foaming methods as an effective adsorbent for Pb in solution. The effects of foaming agent type, foaming agent dosage, alkali dosage, and water glass modulus on the properties of the MSBPM were studied, and the micromorphology and porosity of the MSBPM were observed using microscopy. The influence of pH value, initial concentration, and adsorbent dosage on the Pb adsorption was investigated.
View Article and Find Full Text PDFBackground: The association between exposure to trace elements mixture and the prevalence of kidney stones and the interactions between elements are unclear. The aim of this study was to explore the association between exposure to trace elements mixture and the prevalence of kidney stones and the interactions between the elements.
Methods: A total of 1,244 participants (139 kidney stone formers and 1,105 non-stone former participants) in NHANES 2017-2018 were included.
The tumor microenvironment (TME) contains complex components, of which the most well-known one is the tumor-associated fibroblast (CAF) that participates in the development and progression of tumors. A high abundance of CAFs implies that tumor stroma is also abundant and often predicts a poor prognosis, especially in terms of immunotherapeutic resistance. In this study, DAZ interacting zinc finger protein 1 (DZIP1) was identified to be upregulated in CAFs and malignant epithelial cells based on single-cell sequencing.
View Article and Find Full Text PDFInt J Environ Res Public Health
January 2023
Background: Although several studies have examined the association between chronic kidney disease (CKD) and hyperuricemia (HUA), the direction of the association remains unclear. We aimed to investigate whether there was a bidirectional association between them.
Methods: The present study was conducted in three analyses.
The public health problems caused by schizophrenia are becoming increasingly prominent and can place a huge economic burden on society. This study takes Gansu Province as an example to analyze the level and changing trend of the economic burden of schizophrenia inpatients in economically underdeveloped areas of China. Using a multi-stage stratified cluster sampling method, 39,054 schizophrenics from 197 medical and health institutions in Gansu Province were selected as the research objects, and their medical expenses and related medical records were obtained from the medical information system.
View Article and Find Full Text PDFObjective: The aim of this study was to evaluate the predictive value of the monocyte-to-high-density lipoprotein ratio (MHR) in Kawasaki disease (KD) complicated with coronary artery lesions (CALs) and to construct a nomogram prediction model.
Methods: The medical records of KD inpatients diagnosed in the Department of Pediatrics of Lanzhou University Second Hospital from May 2015 to September 2021 were retrospectively analyzed. ROC curves were applied to evaluate the predictive value of MHR in KD complicated with CALs, and logistic regression analysis was used to screen independent risk factors.
The proper orientation of centrosome and spindle is essential for genome stability; however, the mechanism that governs these processes remains elusive. Here, we demonstrated that polo-like kinase 1 (Plk1), a key mitotic kinase, phosphorylates residue Thr76 in VCP/p97 (an AAA-ATPase), at the centrosome from prophase to anaphase. This phosphorylation process recruits VCP to the centrosome and in this way, it regulates centrosome orientation.
View Article and Find Full Text PDFBackgrounds: Long non-coding RNAs (lncRNAs) function as competing endogenous RNAs (ceRNAs) that contribute to carcinogenesis. Herein, we plan to explore whether lncRNA KCNQ1OT1 modulated miR-423-5p/microfibril-associated protein 2 (MFAP2) signaling axis is implicated in the progression of human colon adenocarcinoma.
Material And Methods: Clinical specimens were collected for histologic examination and gene expression analysis.
Background: To investigate the differences between water immersion (WI) and air insufflation (AI) for colonoscopy under various bowel preparation conditions.
Methods: In this study, 526 outpatients were randomly assigned to two groups, namely a WI group (n = 263) and an AI group (n = 263). During the procedure, the quality of bowel preparation, abdominal pain score, cecal intubation rate (CIR), adenoma detection rate (ADR), the intubation times, and other indicators were recorded.
Stringent leaching conditions including high pressure, temperature, and chemical consumption limit the extraction of valuable metals from circulating fluidized bed-derived high-alumina fly ash (CFB-HAFA) via the acid leaching method. In the present study, a complex utilization of CFB-HAFA, including the extraction of valuable metals (Al, Li, and Ga) and preparation of mesoporous material, is realized via a moderate acid-alkali-based alternate method. The results show that 82, 78, and 69% of Al, Li, and Ga, respectively, in CFB-HAFA are extracted by two treatments of acid leaching under moderate conditions of 15 wt % HCl concentration and 90 °C leaching temperature.
View Article and Find Full Text PDFThis study aims to investigate the effects of regulation of murine double minute protein4 () expression by microRNA (miR)-34a on the proliferation of colorectal cancer LOVO cells. Prediction results obtained using a gene microarray showed that MDM4 is a specific miR-34a target gene. The interaction between miR-34a and the 3'-untranslated region (UTR) of MDM4 was detected using a luciferase reporter system.
View Article and Find Full Text PDFFeed coal, fly ash (FA), and bottom ash (BA) were collected from a 300 MW circulating fluidized bed boiler. A mechanical screen classifier was used to separate and obtain particles with different sizes. The distribution of valuable elements, including aluminum (Al), lithium (Li), and gallium (Ga), and rare earth elements (REE) in the samples was investigated.
View Article and Find Full Text PDFCoal gangue is an inevitable coal waste from coal mine, which results in serious environmental problems. Oxy-fuel firing of coal waste and biomass waste is an alternative technology for efficient and clean utilization and CO reduction of coal waste. In this study, the oxy-fuel combustion characteristics and interactions of coal gangue and pine sawdust were investigated using thermogravimetric analysis, with a focus on the effect of oxygen concentration on interactions between coal gangue and pine sawdust during oxy-fuel combustion.
View Article and Find Full Text PDFCaveolae and associated cavin and caveolins may govern myocardial function, together with responses to mechanical and ischaemic stresses. Abnormalities in these proteins are also implicated in different cardiovascular disorders. However, specific roles of the cavin-1 protein in cardiac and coronary responses to mechanical/metabolic perturbation remain unclear.
View Article and Find Full Text PDFGuang Pu Xue Yu Guang Pu Fen Xi
August 2016
Optical emission spectroscopy (OES) was used to detect the plasma distribution during the depositing process of diamond films with hot filament chemical vapor deposition (HFCVD) method using acetone as carbon source. The surface and cross section of deposited diamond films were characterized by scanning electron microscopy (SEM) and their quality was tested with Raman spectroscopy. OES results showed that the intensity of active species near the center is higher than that in marginal area in the case of linear array of hot filament.
View Article and Find Full Text PDFGuang Pu Xue Yu Guang Pu Fen Xi
November 2015
Polycrystalline diamond growth by microwave plasma chemical vapor deposition (MPCVD) at high-pressure (34.5 kPa) was investigated. The CH₄/H₂/O₂plasma was detected online by optical emission spectroscopy (OES), and the spatial distribution of radicals in the CH₄/H₂/O₂plasma was studied.
View Article and Find Full Text PDFObjective: Large-scale clinical studies have shown that ulcerative colities were related with colorectal cancer. In this study, animal model was established by AOM/DSS method to explore the activation of IL-6-STAT3-SOCS3 signaling pathway and the expression of pathway-related proteins in ulcerative colitis carcinogenesis, in order to lay a foundation for exploring the regulation mechanism of IL-6/STAT3/SOCS3 signaling pathway in ulcerative colitis carcinogenesis.
Method: AOM/DSS modeling method was used to establish animal models of ulcerative colitis carcinogenesis; colonic mucosa specimens were collected at different time points for pathological examination.
Guang Pu Xue Yu Guang Pu Fen Xi
March 2015
Asian Pac J Cancer Prev
July 2015