Background Multiple sclerosis is a chronic, progressive, disabling disease associated with a high rate of infection, evidence of chronic inflammation, and a high mortality rate. Abnormalities of serum cytokines and changes in the activity of inflammatory cells were associated with relapsing-remitting multiple sclerosis (MS-RR). This study aims to introduce new inflammatory ratios derived from hematological and lipid indices as discriminators of T-helper (Th)-1/Th-2 activity in RR-MS.
View Article and Find Full Text PDFBackground: Mature inflammasome markers play a role in the development of Type 1 diabetes (T1D). This cross-sectional study aimed to derive ratios from the serum levels of interleukins (ILs): IL-1β and IL-18 and to relate their values with glycemic index and anti-inflammatory markers (IL-4 and IL-10) in children with T1D.
Materials And Methods: This study was conducted at Hawler Medical University in Erbil-Iraq from April to July 2018.
Background: Human C-reactive protein (CRP) has been used in the risk assessment of coronary events. Human saliva mirrors the body's health and well-being and is noninvasive, easy to collect, and ideal for third-world countries as well as for large patient screening.
Aims: This study aimed to screen the saliva CRP qualitatively in patients with diabetes (Type 1 and 2) taking in considerations, the diagnostic criteria of metabolic syndrome.
Background: Determination of the hematological indices is a useful prognostic laboratory investigation in the cancer research. The neutrophil to lymphocyte ratio (LNR), red cell distribution width (RDW) and the platelet distribution width (PDW) are useful markers for the prediction and the prognosis of breast cancer. The aims of this study were to assess the hematological indices in breast cancer women survivals and to show if there were significant differences in these indices between pre- and postmenopausal women.
View Article and Find Full Text PDFObjectives: There is an association between viral infection and development of diabetes mellitus. This study aimed to investigate the role of rubella virus, cytomegalovirus and coxsackievirus in patients with type 1 (T1D) and type 2 (T2D) diabetes mellitus in respect to the glycemic control and immune response presented by serum γ-interferon leveland antiviral antibodies.
Materials And Methods: A total number of 160 (70 male and 90 female) T1D and 75 T2D (25 male and 50 female) patients allocated randomly from Martyr Layla Qasm center for diabetes mellitus in Erbil, Iraq, were enrolled in the study.
Int J Appl Basic Med Res
July 2011
Background: Contradictory reports about the role of cytokines, particularly interleukins (IL) in atherosclerosis are found in the literature.
Objectives: This study was aimed to investigate the association between the levels of cytokines notably IL-4, IL-12, IL-18 and, the atherogenicity and glycemic control in patients with type 2 diabetes mellitus.
Materials And Methods: Seventy five patients with type 2 diabetes mellitus (25 males and 50 females) attending diabetic clinic during 1st August 2008 to 30th December 2009 as well as seventy healthy subjects (38 males and 32 female) were enrolled in the study.