Publications by authors named "ZhiYong Ji"

Article Synopsis
  • The study investigates the role of the CCL2/CCR2 signaling pathway in neuroinflammation following subarachnoid hemorrhage (SAH) and examines the neuroprotective effects of Bindarit, a CCL2 inhibitor.
  • Analysis of RNA-seq data showed increased CCL2 expression in SAH, and treatment with Bindarit improved neurological deficits and reduced inflammation in both in vivo and in vitro models.
  • The findings suggest that targeting the CCL2/CCR2 pathway with Bindarit may offer therapeutic benefits by enhancing neurological recovery after SAH.
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Objective: Assess the complications, clinical outcomes, and angiographic results of endovascular treatment (EVT) for ruptured intracranial posterior circulation aneurysms in small arteries, and identify their risk factors.

Methods: We conducted a retrospective analysis of 79 patients with ruptured posterior circulation aneurysms in small arteries (the diameter of the parent artery was ≤2 mm) treated at our hospital between January 2014 and August 2023. All patients received EVT.

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To improve the level of modern hospital management and establish a scientific and effective medical equipment maintenance guarantee system, this paper proposes the construction of a dynamic interactive fault repair knowledge base system for magnetic resonance imaging (MRI) equipment based on knowledge graph technology. This innovative application of intelligent management for large medical equipment involves collecting and organizing actual maintenance data. The paper constructs the medical equipment maintenance knowledge base, with MRI equipment as a case study, and initially implements functions such as fault information retrieval, technical guidance, and training and learning for MRI equipment.

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  • The study focuses on the effects of copper on water quality criteria (WQC) and explores the limitations of using regression models to predict copper toxicity due to species-specific factors.
  • It introduces a backpropagation neural network (BPNN) model optimized with a genetic algorithm, which performs better than traditional mixed linear regression (MNLR) models in predicting toxicity values.
  • Results indicate the BPNN model not only enhances predictive accuracy when considering species-specific data but also provides WQC ranges that align with global guidelines, offering a solid foundation for future research in water quality assessment.*
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  • Post-transcriptional regulation by RNA binding proteins is important for male germline development, with the protein IGF2BP1 specifically expressed in male gonads.
  • A study showed that knocking out Igf2bp1 in mice led to age-dependent spermatogenic defects, including fewer undifferentiated spermatogonia and increased cell death.
  • IGF2BP1 is essential for spermatogenesis, as it regulates the mRNA of Lin28a, which is crucial for the expansion of spermatogonia.
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Organic luminogens with dual-state emission (DSE) have garnered widespread attention due to their versatility in the forms of both dilute solutions and solids. Despite the growing interest, most research on DSE focuses primarily on molecule design and photophysical investigation, with limited exploration of their practical applications. In this study, we introduce a novel fluorescent molecule, PCT, featuring a distinct D-π(A)-D' electronic structure.

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Article Synopsis
  • - The study analyzed 194 patients treated for ruptured intracranial aneurysms, finding that 29.4% experienced complications during hospitalization, with an overall mortality rate of 11.9%.
  • - After a median follow-up of nearly 46.5 months, 81.4% of patients had favorable outcomes, while 18.5% had unfavorable results, leading to 1-year and 5-year survival rates of 89.5% and 85.4%, respectively.
  • - Key risk factors for complications included involvement of the basilar artery and use of external ventricular drainage; for unfavorable outcomes, advanced age and poor initial health status were significant predictors.
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Combining medical IoT and artificial intelligence technology is an effective approach to achieve the intelligence of medical equipment. This integration can address issues such as low image quality caused by fluctuations in power quality and potential equipment damage, and this study proposes a predictive model, ISSA-TCN-BiLSTM, based on a bi-directional long short-term memory network (BiLSTM). Firstly, power quality data and other data from MRI and CT equipment within a 6-month period are collected using current fingerprint technology.

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Background: Glioblastoma is the most common type of brain cancer, with a prognosis that is unfortunately poor. Despite considerable progress in the field, the intricate molecular basis of this cancer remains elusive.

Aim: The aim of this study was to identify genetic indicators of glioblastoma and reveal the processes behind its development.

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Conventional solarizing seawater suffers from inefficiency and space constraints. Interfacial solar vapor generation (ISVG) presents an energy-efficient alternative, yet the scalability, adaptability, and durability of a solar evaporator for practical use are remaining concerns. Herein, a hydrogen-bond-repairing solar evaporator featuring reconstructed large-width channels is proposed for ongoing solarization of seawater in ISVG.

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Background: Patients with symptomatic chronic internal carotid artery occlusion (ICAO) face a high risk of recurrent stroke despite receiving aggressive medical therapy. This study aimed to evaluate the effectiveness and safety of hybrid surgery in treating symptomatic chronic ICAO.

Methods: This retrospective case series was conducted at a single center.

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  • Researchers created new membranes using polyether ether ketone-based polymers with ion-cross-linkable quaternary ammonium and acidic side chains to selectively allow certain cations to pass through.
  • They explored three types of acidic groups (sulfonic acid, carboxylic acid, and phenolic hydroxyl) that form ionic links in the membranes, influencing their structure and performance.
  • The study found that while cation flux improved with increased acidity, the selectivity varied, with carboxyl group membranes showing the best selectivity for lithium over magnesium, outperforming existing commercial membranes.
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Primate-specific DAZ (deleted in azoospermia) has evolved in the azoospermia factor c (AZFc) locus on the Y chromosome. Loss of DAZ is associated with azoospermia in patients with deletion of the AZFc region (AZFc_del). However, the molecular mechanisms of DAZ in spermatogenesis remain uncertain.

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Achieving separation of lithium and magnesium with similar radii is crucial for the current lithium extraction technology from salt lakes, which usually possess a high lithium-to-magnesium ratio. Herein, we proposed the facile sequential interfacial polymerization (SIP) approach to construct electronanofiltration membranes (ENFMs) with a bilayer charged structure consisting of a high positively charged surface and a negatively charged sublayer. The trimesoyl chloride (TMC) concentration was adjusted to enhance the -COOH content and negative charge of the polyamide sublayer to promote Li migration, and then the quaternized polyethylenimine was introduced to the membrane surface by the SIP process to increase the positive charge density on the surface of the ENFMs, which would block the migration of Mg and enhance the Li/Mg selectivity of the ENFMs.

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Aqueous solutions of magnesium chloride (MgCl(aq)) are often used to test advances in the theory of electrolyte solutions because they are considered an ideal strong 2:1 electrolyte. However, there is evidence that some ion association occurs in these solutions, even at low concentrations. Even a small ion-pairing constant can have a significant impact on the chemical speciation of ions, so it is important to determine whether ion pairing actually occurs.

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Objective: To analyze the medical equipment operation data of 44 clinical departments in the hospital from three aspects: materials and consumables, operation and maintenance depreciation, and operation management.

Methods: To formulate the evaluation standards and scoring criteria for the operation indicators, the lowest score is 0 points, and the highest score is 5 points. Based on the operation indicators of medical equipment, establish a hierarchical structure model, determine the criterion layer and sub-criteria layer, construct a judgment matrix, normalize it, and calculate the weight coefficient.

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Selective electrodialysis is a promising approach to recovering K from complex coexisting ionic systems. In this study, the effects of current density, the concentration of K and Mg, as well as the operating temperature on the separation process of K and Mg were explored to investigate the competitive migration of mono- and multivalent ions, offering a guide for the design of selective electrodialysis process, and therefore obtain the desired aqueous solutions containing K and Mg. The results show that ion concentration played a critical role in determining the selectivity of separation between K and Mg.

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Internet of Things plays a vital role in the field of healthcare. Smart medical devices, innovative sensors and lightweight communication protocols are making the Internet of Medical Things possible. This paper summarizes the research progress of Internet of Things technology in medical engineering from two aspects of health monitoring system and ingestible sensor monitoring equipment.

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The treatment of wastewater has become increasingly challenging as a result of its growing complexity. To achieve synergistic removal of coexisting pollutants in wastewater, one promising approach involves the integration of electric fields. We conducted a comprehensive literature review to explore the potential of integrating electric fields and developing efficient electro-intensified simultaneous decontamination systems for wastewater containing coexisting pollutants.

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Continuously increasing demand for the life-critical water resource induces severe global water shortages. It is imperative to advance effective, economic, and environmentally sustainable strategies to augment clean water supply. The present work reviews recent reports on the interfacial engineering to devices design of solar vapor generation (SVG) system for boosting the viability of drinkable water harvesting.

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Background: A recent trial failed to show any benefit of stenting plus medical therapy over medical therapy alone in patients with symptomatic intracranial stenosis. We aimed to examine whether the symptomatic qualifying artery modifies the effect of stenting plus medical therapy.

Methods: This is a post-hoc analysis of the CASSISS trial that included patients with symptomatic intracranial stenosis, randomly assigned to undergo stenting plus medical therapy or medical therapy alone; 358/380 patients were included.

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Meiotic arrest is a common pathologic phenotype of non-obstructive azoospermia (NOA), yet its genetic causes require further investigation. Meiotic nuclear divisions 1 (MND1) has been proved to be indispensable for meiotic recombination in many species. To date, only one variant of MND1 has been reported associated with primary ovarian insufficiency (POI), yet there has been no report of variants in MND1 associated with NOA.

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In this paper, an electronically controlled diesel engine fueled with Fischer-Tropsch fuel was selected to optimize soot and NO emissions. First, the effects of injection parameters on exhaust performance and combustion properties were studied on an engine test bench and then a prediction model based on a support vector machine (SVM) was established according to the test results. On this basis, a decision analysis of soot and NO solutions assigned with different weights was performed based on the TOPSIS analysis method.

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Background: It is necessary to explore the safety and efficacy of various endovascular treatment techniques in the treatment of patients with intracranial vertebrobasilar trunk dissecting aneurysms (VBTDAs). This study sought to compare the clinical and angiographic outcomes of patients with intracranial VBTDAs following low-profile visualized intraluminal support (LVIS)-within-Enterprise overlapping-stent technique with those of flow diversion (FD).

Methods: This was a retrospective, observational, cohort study.

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Objective: This study aimed to evaluate the feasibility of the low-profile visualized intraluminal support (LVIS)-within-enterprise double-stent technique for patients with acutely ruptured intracranial vertebrobasilar artery-dissecting aneurysms (ari-VBDAs).

Methods: A total of 30 patients with ari-VBDAs who underwent reconstructive treatment using LVIS-within-enterprise double-stent technique with coil embolization between January 2014 and May 2022 were retrospectively enrolled. Patients' characteristics and clinical and imaging outcomes were reviewed.

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